Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 534.6 BDBM495088

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcitonin gene-related peptide type 1 receptor (Homo sapiens (Human))	BDBM495088 (US10995084, Ex. No. 4A-3) Show SMILES CC(c1ccc(cc1C)C(=O)NCC(=O)N1[C@@H](CC[C@@H]1C(C)(C)O)c1cccc(F)c1)c1cc(C)n[nH]c1=O |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.280	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
KISSEI PHARMACEUTICAL CO., LTD. US Patent					Assay Description The binding affinity assay of compounds for human CGRP receptor was carried out by inhibition of radiolabeled ligand [125I]-CGRP binding in human neu...				US Patent US10995084 (2021) BindingDB Entry DOI: 10.7270/Q24T6NH0
					More data for this Ligand-Target Pair