Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Endothelin-converting enzyme 1
(Rattus norvegicus (Rat)) | BDBM50368806
(CHEMBL1791099)Show SMILES CC[C@@H](C)[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H]([C@H](C)CC)C(=O)N[C@@H](CC(C)C)C(O)CC(=O)NC[C@@H](C)O Show InChI InChI=1S/C28H54N4O7/c1-11-17(5)23(31-26(37)24(18(6)12-2)32-27(38)39-28(8,9)10)25(36)30-20(13-16(3)4)21(34)14-22(35)29-15-19(7)33/h16-21,23-24,33-34H,11-15H2,1-10H3,(H,29,35)(H,30,36)(H,31,37)(H,32,38)/t17-,18-,19-,20+,21?,23+,24+/m1/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane. |
J Med Chem 36: 468-78 (1993)
BindingDB Entry DOI: 10.7270/Q2PC331F |
More data for this
Ligand-Target Pair | |
Cathepsin D
(Bos taurus) | BDBM50368806
(CHEMBL1791099)Show SMILES CC[C@@H](C)[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H]([C@H](C)CC)C(=O)N[C@@H](CC(C)C)C(O)CC(=O)NC[C@@H](C)O Show InChI InChI=1S/C28H54N4O7/c1-11-17(5)23(31-26(37)24(18(6)12-2)32-27(38)39-28(8,9)10)25(36)30-20(13-16(3)4)21(34)14-22(35)29-15-19(7)33/h16-21,23-24,33-34H,11-15H2,1-10H3,(H,29,35)(H,30,36)(H,31,37)(H,32,38)/t17-,18-,19-,20+,21?,23+,24+/m1/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of conversion of hemoglobin by commercially purchased bovine spleen cathepsin D. |
J Med Chem 36: 468-78 (1993)
BindingDB Entry DOI: 10.7270/Q2PC331F |
More data for this
Ligand-Target Pair | |