Found 3 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Endothelin-converting enzyme 1
(Rattus norvegicus (Rat)) | BDBM50368815
(CHEMBL1791105)Show SMILES CC[C@@H](C)[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H]([C@H](C)CC)C(=O)N[C@@H](Cc1cccc2ccccc12)[C@@H](O)[C@@H](O)CC(C)C Show InChI InChI=1S/C35H55N3O6/c1-10-22(5)29(37-33(42)30(23(6)11-2)38-34(43)44-35(7,8)9)32(41)36-27(31(40)28(39)19-21(3)4)20-25-17-14-16-24-15-12-13-18-26(24)25/h12-18,21-23,27-31,39-40H,10-11,19-20H2,1-9H3,(H,36,41)(H,37,42)(H,38,43)/t22-,23-,27+,28+,29+,30+,31-/m1/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 660 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of conversion of big endothelial-1 (Big ET-1) to ET-1 by endothelin converting enzyme(ECE) in rat lung membrane. |
J Med Chem 36: 468-78 (1993)
BindingDB Entry DOI: 10.7270/Q2PC331F |
More data for this
Ligand-Target Pair | |
Renin
(Homo sapiens (Human)) | BDBM50368815
(CHEMBL1791105)Show SMILES CC[C@@H](C)[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H]([C@H](C)CC)C(=O)N[C@@H](Cc1cccc2ccccc12)[C@@H](O)[C@@H](O)CC(C)C Show InChI InChI=1S/C35H55N3O6/c1-10-22(5)29(37-33(42)30(23(6)11-2)38-34(43)44-35(7,8)9)32(41)36-27(31(40)28(39)19-21(3)4)20-25-17-14-16-24-15-12-13-18-26(24)25/h12-18,21-23,27-31,39-40H,10-11,19-20H2,1-9H3,(H,36,41)(H,37,42)(H,38,43)/t22-,23-,27+,28+,29+,30+,31-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | 6.0 | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
In vitro inhibition of partially purified human renin at pH 6.0. |
J Med Chem 36: 468-78 (1993)
BindingDB Entry DOI: 10.7270/Q2PC331F |
More data for this
Ligand-Target Pair | |
Cathepsin D
(Bos taurus) | BDBM50368815
(CHEMBL1791105)Show SMILES CC[C@@H](C)[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H]([C@H](C)CC)C(=O)N[C@@H](Cc1cccc2ccccc12)[C@@H](O)[C@@H](O)CC(C)C Show InChI InChI=1S/C35H55N3O6/c1-10-22(5)29(37-33(42)30(23(6)11-2)38-34(43)44-35(7,8)9)32(41)36-27(31(40)28(39)19-21(3)4)20-25-17-14-16-24-15-12-13-18-26(24)25/h12-18,21-23,27-31,39-40H,10-11,19-20H2,1-9H3,(H,36,41)(H,37,42)(H,38,43)/t22-,23-,27+,28+,29+,30+,31-/m1/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of conversion of hemoglobin by commercially purchased bovine spleen cathepsin D. |
J Med Chem 36: 468-78 (1993)
BindingDB Entry DOI: 10.7270/Q2PC331F |
More data for this
Ligand-Target Pair | |