Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 435.5 BDBM365992

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Programmed cell death 1 ligand 1 (Homo sapiens (Human))	BDBM365992 ((2S)-2-[({2,6-dimethoxy-4-[(2- methyl-3- phenylphe...) Show SMILES CC[C@@H](CO)NCc1c(OC)cc(OCc2cccc(c2C)-c2ccccc2)cc1OC |r| Show InChI InChI=1S/C27H33NO4/c1-5-22(17-29)28-16-25-26(30-3)14-23(15-27(25)31-4)32-18-21-12-9-13-24(19(21)2)20-10-7-6-8-11-20/h6-15,22,28-29H,5,16-18H2,1-4H3/t22-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharmaceuticals					Assay Description All binding studies were performed in an HTRF assay buffer consisting of dPBS supplemented with 0.1% (withv) bovine serum albumin and 0.05% (v/v) Twe...				J Med Chem 51: 4-16 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B42
					More data for this Ligand-Target Pair