Found 4 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50495019
(CHEMBL3099660)Show SMILES CC[C@@H](Cc1ccc(OC)cc1)NC[C@H](O)c1cc(O)cc(O)c1 |r| Show InChI InChI=1S/C19H25NO4/c1-3-15(8-13-4-6-18(24-2)7-5-13)20-12-19(23)14-9-16(21)11-17(22)10-14/h4-7,9-11,15,19-23H,3,8,12H2,1-2H3/t15-,19-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 4.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Medical University of Lublin
Curated by ChEMBL
| Assay Description Displacement of [3H]-(R,R')-methoxyfenoterol from human beta2 adrenergic receptor expressed in HEK cells by liquid scintillation counting analysis |
Bioorg Med Chem 22: 234-46 (2014)
Article DOI: 10.1016/j.bmc.2013.11.030 BindingDB Entry DOI: 10.7270/Q2251N5F |
More data for this Ligand-Target Pair | |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50495019
(CHEMBL3099660)Show SMILES CC[C@@H](Cc1ccc(OC)cc1)NC[C@H](O)c1cc(O)cc(O)c1 |r| Show InChI InChI=1S/C19H25NO4/c1-3-15(8-13-4-6-18(24-2)7-5-13)20-12-19(23)14-9-16(21)11-17(22)10-14/h4-7,9-11,15,19-23H,3,8,12H2,1-2H3/t15-,19-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 4.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Medical University of Lublin
Curated by ChEMBL
| Assay Description Displacement of [3H]-(R,R')-methoxyfenoterol from human beta2 adrenergic receptor expressed in HEK cells by liquid scintillation counting analysis |
Bioorg Med Chem 22: 234-46 (2014)
Article DOI: 10.1016/j.bmc.2013.11.030 BindingDB Entry DOI: 10.7270/Q2251N5F |
More data for this Ligand-Target Pair | |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50495019
(CHEMBL3099660)Show SMILES CC[C@@H](Cc1ccc(OC)cc1)NC[C@H](O)c1cc(O)cc(O)c1 |r| Show InChI InChI=1S/C19H25NO4/c1-3-15(8-13-4-6-18(24-2)7-5-13)20-12-19(23)14-9-16(21)11-17(22)10-14/h4-7,9-11,15,19-23H,3,8,12H2,1-2H3/t15-,19-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 2.01E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Medical University of Lublin
Curated by ChEMBL
| Assay Description Displacement of [3H]-CGP-12177 from human beta2 adrenergic receptor expressed in HEK cells by liquid scintillation counting analysis |
Bioorg Med Chem 22: 234-46 (2014)
Article DOI: 10.1016/j.bmc.2013.11.030 BindingDB Entry DOI: 10.7270/Q2251N5F |
More data for this Ligand-Target Pair | |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50495019
(CHEMBL3099660)Show SMILES CC[C@@H](Cc1ccc(OC)cc1)NC[C@H](O)c1cc(O)cc(O)c1 |r| Show InChI InChI=1S/C19H25NO4/c1-3-15(8-13-4-6-18(24-2)7-5-13)20-12-19(23)14-9-16(21)11-17(22)10-14/h4-7,9-11,15,19-23H,3,8,12H2,1-2H3/t15-,19-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 1.01E+3 | n/a | n/a | n/a | n/a |
Medical University of Lublin
Curated by ChEMBL
| Assay Description Agonist activity at human beta2 adrenergic receptor expressed in HEK293 cells assessed as stimulation of cAMP accumulation |
Bioorg Med Chem 22: 234-46 (2014)
Article DOI: 10.1016/j.bmc.2013.11.030 BindingDB Entry DOI: 10.7270/Q2251N5F |
More data for this Ligand-Target Pair | |