Found 16 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Neuropeptide Y receptor type 4
(Homo sapiens (Human)) | BDBM50466536
(CHEMBL4279973)Show SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(C)[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O |r| Show InChI InChI=1S/C181H280N52O55/c1-18-92(12)142(186)170(280)212-114(28-19-20-62-182)175(285)232-68-26-34-131(232)168(278)210-110(53-59-138(247)248)147(257)204-95(15)173(283)231-67-25-33-130(231)166(276)200-83-136(244)205-109(52-58-137(245)246)151(261)224-125(81-141(253)254)155(265)203-94(14)146(256)227-128(85-235)176(286)233-69-27-35-132(233)169(279)211-112(55-61-140(251)252)152(262)208-111(54-60-139(249)250)153(263)214-116(71-88(4)5)157(267)222-123(79-134(184)242)162(272)207-106(29-21-63-196-178(187)188)148(258)218-120(75-98-38-46-103(238)47-39-98)160(270)219-119(74-97-36-44-102(237)45-37-97)154(264)202-93(13)145(255)226-127(84-234)165(275)217-115(70-87(2)3)156(266)206-107(30-22-64-197-179(189)190)149(259)221-122(78-101-82-195-86-201-101)161(271)220-121(76-99-40-48-104(239)49-41-99)159(269)215-117(72-89(6)7)158(268)223-124(80-135(185)243)163(273)216-118(73-90(8)9)164(274)228-143(91(10)11)171(281)229-144(96(16)236)172(282)213-113(32-24-66-199-181(193)194)174(284)230(17)129(56-57-133(183)241)167(277)209-108(31-23-65-198-180(191)192)150(260)225-126(177(287)288)77-100-42-50-105(240)51-43-100/h36-51,82,86-96,106-132,142-144,234-240H,18-35,52-81,83-85,182,186H2,1-17H3,(H2,183,241)(H2,184,242)(H2,185,243)(H,195,201)(H,200,276)(H,202,264)(H,203,265)(H,204,257)(H,205,244)(H,206,266)(H,207,272)(H,208,262)(H,209,277)(H,210,278)(H,211,279)(H,212,280)(H,213,282)(H,214,263)(H,215,269)(H,216,273)(H,217,275)(H,218,258)(H,219,270)(H,220,271)(H,221,259)(H,222,267)(H,223,268)(H,224,261)(H,225,260)(H,226,255)(H,227,256)(H,228,274)(H,229,281)(H,245,246)(H,247,248)(H,249,250)(H,251,252)(H,253,254)(H,287,288)(H4,187,188,196)(H4,189,190,197)(H4,191,192,198)(H4,193,194,199)/t92-,93-,94-,95-,96+,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,142-,143-,144-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| 0.158 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [125I]-PP from human Y4R expressed in CHO-K1 cell membranes after 2 hrs by scintillation proximity assay |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 4
(Homo sapiens (Human)) | BDBM50466536
(CHEMBL4279973)Show SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(C)[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O |r| Show InChI InChI=1S/C181H280N52O55/c1-18-92(12)142(186)170(280)212-114(28-19-20-62-182)175(285)232-68-26-34-131(232)168(278)210-110(53-59-138(247)248)147(257)204-95(15)173(283)231-67-25-33-130(231)166(276)200-83-136(244)205-109(52-58-137(245)246)151(261)224-125(81-141(253)254)155(265)203-94(14)146(256)227-128(85-235)176(286)233-69-27-35-132(233)169(279)211-112(55-61-140(251)252)152(262)208-111(54-60-139(249)250)153(263)214-116(71-88(4)5)157(267)222-123(79-134(184)242)162(272)207-106(29-21-63-196-178(187)188)148(258)218-120(75-98-38-46-103(238)47-39-98)160(270)219-119(74-97-36-44-102(237)45-37-97)154(264)202-93(13)145(255)226-127(84-234)165(275)217-115(70-87(2)3)156(266)206-107(30-22-64-197-179(189)190)149(259)221-122(78-101-82-195-86-201-101)161(271)220-121(76-99-40-48-104(239)49-41-99)159(269)215-117(72-89(6)7)158(268)223-124(80-135(185)243)163(273)216-118(73-90(8)9)164(274)228-143(91(10)11)171(281)229-144(96(16)236)172(282)213-113(32-24-66-199-181(193)194)174(284)230(17)129(56-57-133(183)241)167(277)209-108(31-23-65-198-180(191)192)150(260)225-126(177(287)288)77-100-42-50-105(240)51-43-100/h36-51,82,86-96,106-132,142-144,234-240H,18-35,52-81,83-85,182,186H2,1-17H3,(H2,183,241)(H2,184,242)(H2,185,243)(H,195,201)(H,200,276)(H,202,264)(H,203,265)(H,204,257)(H,205,244)(H,206,266)(H,207,272)(H,208,262)(H,209,277)(H,210,278)(H,211,279)(H,212,280)(H,213,282)(H,214,263)(H,215,269)(H,216,273)(H,217,275)(H,218,258)(H,219,270)(H,220,271)(H,221,259)(H,222,267)(H,223,268)(H,224,261)(H,225,260)(H,226,255)(H,227,256)(H,228,274)(H,229,281)(H,245,246)(H,247,248)(H,249,250)(H,251,252)(H,253,254)(H,287,288)(H4,187,188,196)(H4,189,190,197)(H4,191,192,198)(H4,193,194,199)/t92-,93-,94-,95-,96+,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,142-,143-,144-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 0.160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [125I]-PP from human Y4R expressed in CHO-K1 cell membranes after 2 hrs by scintillation proximity assay |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 1
(Homo sapiens (Human)) | BDBM50466536
(CHEMBL4279973)Show SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(C)[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O |r| Show InChI InChI=1S/C181H280N52O55/c1-18-92(12)142(186)170(280)212-114(28-19-20-62-182)175(285)232-68-26-34-131(232)168(278)210-110(53-59-138(247)248)147(257)204-95(15)173(283)231-67-25-33-130(231)166(276)200-83-136(244)205-109(52-58-137(245)246)151(261)224-125(81-141(253)254)155(265)203-94(14)146(256)227-128(85-235)176(286)233-69-27-35-132(233)169(279)211-112(55-61-140(251)252)152(262)208-111(54-60-139(249)250)153(263)214-116(71-88(4)5)157(267)222-123(79-134(184)242)162(272)207-106(29-21-63-196-178(187)188)148(258)218-120(75-98-38-46-103(238)47-39-98)160(270)219-119(74-97-36-44-102(237)45-37-97)154(264)202-93(13)145(255)226-127(84-234)165(275)217-115(70-87(2)3)156(266)206-107(30-22-64-197-179(189)190)149(259)221-122(78-101-82-195-86-201-101)161(271)220-121(76-99-40-48-104(239)49-41-99)159(269)215-117(72-89(6)7)158(268)223-124(80-135(185)243)163(273)216-118(73-90(8)9)164(274)228-143(91(10)11)171(281)229-144(96(16)236)172(282)213-113(32-24-66-199-181(193)194)174(284)230(17)129(56-57-133(183)241)167(277)209-108(31-23-65-198-180(191)192)150(260)225-126(177(287)288)77-100-42-50-105(240)51-43-100/h36-51,82,86-96,106-132,142-144,234-240H,18-35,52-81,83-85,182,186H2,1-17H3,(H2,183,241)(H2,184,242)(H2,185,243)(H,195,201)(H,200,276)(H,202,264)(H,203,265)(H,204,257)(H,205,244)(H,206,266)(H,207,272)(H,208,262)(H,209,277)(H,210,278)(H,211,279)(H,212,280)(H,213,282)(H,214,263)(H,215,269)(H,216,273)(H,217,275)(H,218,258)(H,219,270)(H,220,271)(H,221,259)(H,222,267)(H,223,268)(H,224,261)(H,225,260)(H,226,255)(H,227,256)(H,228,274)(H,229,281)(H,245,246)(H,247,248)(H,249,250)(H,251,252)(H,253,254)(H,287,288)(H4,187,188,196)(H4,189,190,197)(H4,191,192,198)(H4,193,194,199)/t92-,93-,94-,95-,96+,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,142-,143-,144-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 0.398 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [125I]-PYY(1 to 36 residues) from human Y1R expressed in BHK-21 cell membranes after 2 hrs by scintillation proximity assay |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 1
(Homo sapiens (Human)) | BDBM50466536
(CHEMBL4279973)Show SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(C)[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O |r| Show InChI InChI=1S/C181H280N52O55/c1-18-92(12)142(186)170(280)212-114(28-19-20-62-182)175(285)232-68-26-34-131(232)168(278)210-110(53-59-138(247)248)147(257)204-95(15)173(283)231-67-25-33-130(231)166(276)200-83-136(244)205-109(52-58-137(245)246)151(261)224-125(81-141(253)254)155(265)203-94(14)146(256)227-128(85-235)176(286)233-69-27-35-132(233)169(279)211-112(55-61-140(251)252)152(262)208-111(54-60-139(249)250)153(263)214-116(71-88(4)5)157(267)222-123(79-134(184)242)162(272)207-106(29-21-63-196-178(187)188)148(258)218-120(75-98-38-46-103(238)47-39-98)160(270)219-119(74-97-36-44-102(237)45-37-97)154(264)202-93(13)145(255)226-127(84-234)165(275)217-115(70-87(2)3)156(266)206-107(30-22-64-197-179(189)190)149(259)221-122(78-101-82-195-86-201-101)161(271)220-121(76-99-40-48-104(239)49-41-99)159(269)215-117(72-89(6)7)158(268)223-124(80-135(185)243)163(273)216-118(73-90(8)9)164(274)228-143(91(10)11)171(281)229-144(96(16)236)172(282)213-113(32-24-66-199-181(193)194)174(284)230(17)129(56-57-133(183)241)167(277)209-108(31-23-65-198-180(191)192)150(260)225-126(177(287)288)77-100-42-50-105(240)51-43-100/h36-51,82,86-96,106-132,142-144,234-240H,18-35,52-81,83-85,182,186H2,1-17H3,(H2,183,241)(H2,184,242)(H2,185,243)(H,195,201)(H,200,276)(H,202,264)(H,203,265)(H,204,257)(H,205,244)(H,206,266)(H,207,272)(H,208,262)(H,209,277)(H,210,278)(H,211,279)(H,212,280)(H,213,282)(H,214,263)(H,215,269)(H,216,273)(H,217,275)(H,218,258)(H,219,270)(H,220,271)(H,221,259)(H,222,267)(H,223,268)(H,224,261)(H,225,260)(H,226,255)(H,227,256)(H,228,274)(H,229,281)(H,245,246)(H,247,248)(H,249,250)(H,251,252)(H,253,254)(H,287,288)(H4,187,188,196)(H4,189,190,197)(H4,191,192,198)(H4,193,194,199)/t92-,93-,94-,95-,96+,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,142-,143-,144-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 0.400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [125I]-PYY(1 to 36 residues) from human Y1R expressed in BHK-21 cell membranes after 2 hrs by scintillation proximity assay |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50466536
(CHEMBL4279973)Show SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(C)[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O |r| Show InChI InChI=1S/C181H280N52O55/c1-18-92(12)142(186)170(280)212-114(28-19-20-62-182)175(285)232-68-26-34-131(232)168(278)210-110(53-59-138(247)248)147(257)204-95(15)173(283)231-67-25-33-130(231)166(276)200-83-136(244)205-109(52-58-137(245)246)151(261)224-125(81-141(253)254)155(265)203-94(14)146(256)227-128(85-235)176(286)233-69-27-35-132(233)169(279)211-112(55-61-140(251)252)152(262)208-111(54-60-139(249)250)153(263)214-116(71-88(4)5)157(267)222-123(79-134(184)242)162(272)207-106(29-21-63-196-178(187)188)148(258)218-120(75-98-38-46-103(238)47-39-98)160(270)219-119(74-97-36-44-102(237)45-37-97)154(264)202-93(13)145(255)226-127(84-234)165(275)217-115(70-87(2)3)156(266)206-107(30-22-64-197-179(189)190)149(259)221-122(78-101-82-195-86-201-101)161(271)220-121(76-99-40-48-104(239)49-41-99)159(269)215-117(72-89(6)7)158(268)223-124(80-135(185)243)163(273)216-118(73-90(8)9)164(274)228-143(91(10)11)171(281)229-144(96(16)236)172(282)213-113(32-24-66-199-181(193)194)174(284)230(17)129(56-57-133(183)241)167(277)209-108(31-23-65-198-180(191)192)150(260)225-126(177(287)288)77-100-42-50-105(240)51-43-100/h36-51,82,86-96,106-132,142-144,234-240H,18-35,52-81,83-85,182,186H2,1-17H3,(H2,183,241)(H2,184,242)(H2,185,243)(H,195,201)(H,200,276)(H,202,264)(H,203,265)(H,204,257)(H,205,244)(H,206,266)(H,207,272)(H,208,262)(H,209,277)(H,210,278)(H,211,279)(H,212,280)(H,213,282)(H,214,263)(H,215,269)(H,216,273)(H,217,275)(H,218,258)(H,219,270)(H,220,271)(H,221,259)(H,222,267)(H,223,268)(H,224,261)(H,225,260)(H,226,255)(H,227,256)(H,228,274)(H,229,281)(H,245,246)(H,247,248)(H,249,250)(H,251,252)(H,253,254)(H,287,288)(H4,187,188,196)(H4,189,190,197)(H4,191,192,198)(H4,193,194,199)/t92-,93-,94-,95-,96+,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,142-,143-,144-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [125I]-PYY(1 to 36 residues) from human Y2R expressed in CHO cell membranes after 2 hrs by scintillation proximity assay |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50466536
(CHEMBL4279973)Show SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(C)[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O |r| Show InChI InChI=1S/C181H280N52O55/c1-18-92(12)142(186)170(280)212-114(28-19-20-62-182)175(285)232-68-26-34-131(232)168(278)210-110(53-59-138(247)248)147(257)204-95(15)173(283)231-67-25-33-130(231)166(276)200-83-136(244)205-109(52-58-137(245)246)151(261)224-125(81-141(253)254)155(265)203-94(14)146(256)227-128(85-235)176(286)233-69-27-35-132(233)169(279)211-112(55-61-140(251)252)152(262)208-111(54-60-139(249)250)153(263)214-116(71-88(4)5)157(267)222-123(79-134(184)242)162(272)207-106(29-21-63-196-178(187)188)148(258)218-120(75-98-38-46-103(238)47-39-98)160(270)219-119(74-97-36-44-102(237)45-37-97)154(264)202-93(13)145(255)226-127(84-234)165(275)217-115(70-87(2)3)156(266)206-107(30-22-64-197-179(189)190)149(259)221-122(78-101-82-195-86-201-101)161(271)220-121(76-99-40-48-104(239)49-41-99)159(269)215-117(72-89(6)7)158(268)223-124(80-135(185)243)163(273)216-118(73-90(8)9)164(274)228-143(91(10)11)171(281)229-144(96(16)236)172(282)213-113(32-24-66-199-181(193)194)174(284)230(17)129(56-57-133(183)241)167(277)209-108(31-23-65-198-180(191)192)150(260)225-126(177(287)288)77-100-42-50-105(240)51-43-100/h36-51,82,86-96,106-132,142-144,234-240H,18-35,52-81,83-85,182,186H2,1-17H3,(H2,183,241)(H2,184,242)(H2,185,243)(H,195,201)(H,200,276)(H,202,264)(H,203,265)(H,204,257)(H,205,244)(H,206,266)(H,207,272)(H,208,262)(H,209,277)(H,210,278)(H,211,279)(H,212,280)(H,213,282)(H,214,263)(H,215,269)(H,216,273)(H,217,275)(H,218,258)(H,219,270)(H,220,271)(H,221,259)(H,222,267)(H,223,268)(H,224,261)(H,225,260)(H,226,255)(H,227,256)(H,228,274)(H,229,281)(H,245,246)(H,247,248)(H,249,250)(H,251,252)(H,253,254)(H,287,288)(H4,187,188,196)(H4,189,190,197)(H4,191,192,198)(H4,193,194,199)/t92-,93-,94-,95-,96+,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,142-,143-,144-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [125I]-PYY(1 to 36 residues) from human Y2R expressed in CHO cell membranes after 2 hrs by scintillation proximity assay |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50466536
(CHEMBL4279973)Show SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(C)[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O |r| Show InChI InChI=1S/C181H280N52O55/c1-18-92(12)142(186)170(280)212-114(28-19-20-62-182)175(285)232-68-26-34-131(232)168(278)210-110(53-59-138(247)248)147(257)204-95(15)173(283)231-67-25-33-130(231)166(276)200-83-136(244)205-109(52-58-137(245)246)151(261)224-125(81-141(253)254)155(265)203-94(14)146(256)227-128(85-235)176(286)233-69-27-35-132(233)169(279)211-112(55-61-140(251)252)152(262)208-111(54-60-139(249)250)153(263)214-116(71-88(4)5)157(267)222-123(79-134(184)242)162(272)207-106(29-21-63-196-178(187)188)148(258)218-120(75-98-38-46-103(238)47-39-98)160(270)219-119(74-97-36-44-102(237)45-37-97)154(264)202-93(13)145(255)226-127(84-234)165(275)217-115(70-87(2)3)156(266)206-107(30-22-64-197-179(189)190)149(259)221-122(78-101-82-195-86-201-101)161(271)220-121(76-99-40-48-104(239)49-41-99)159(269)215-117(72-89(6)7)158(268)223-124(80-135(185)243)163(273)216-118(73-90(8)9)164(274)228-143(91(10)11)171(281)229-144(96(16)236)172(282)213-113(32-24-66-199-181(193)194)174(284)230(17)129(56-57-133(183)241)167(277)209-108(31-23-65-198-180(191)192)150(260)225-126(177(287)288)77-100-42-50-105(240)51-43-100/h36-51,82,86-96,106-132,142-144,234-240H,18-35,52-81,83-85,182,186H2,1-17H3,(H2,183,241)(H2,184,242)(H2,185,243)(H,195,201)(H,200,276)(H,202,264)(H,203,265)(H,204,257)(H,205,244)(H,206,266)(H,207,272)(H,208,262)(H,209,277)(H,210,278)(H,211,279)(H,212,280)(H,213,282)(H,214,263)(H,215,269)(H,216,273)(H,217,275)(H,218,258)(H,219,270)(H,220,271)(H,221,259)(H,222,267)(H,223,268)(H,224,261)(H,225,260)(H,226,255)(H,227,256)(H,228,274)(H,229,281)(H,245,246)(H,247,248)(H,249,250)(H,251,252)(H,253,254)(H,287,288)(H4,187,188,196)(H4,189,190,197)(H4,191,192,198)(H4,193,194,199)/t92-,93-,94-,95-,96+,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,142-,143-,144-/m0/s1 | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [125I]-PYY(1 to 36 residues) from human Y5R expressed in HEK293 cell membranes after 2 hrs by scintillation proximity assay |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50466536
(CHEMBL4279973)Show SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(C)[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O |r| Show InChI InChI=1S/C181H280N52O55/c1-18-92(12)142(186)170(280)212-114(28-19-20-62-182)175(285)232-68-26-34-131(232)168(278)210-110(53-59-138(247)248)147(257)204-95(15)173(283)231-67-25-33-130(231)166(276)200-83-136(244)205-109(52-58-137(245)246)151(261)224-125(81-141(253)254)155(265)203-94(14)146(256)227-128(85-235)176(286)233-69-27-35-132(233)169(279)211-112(55-61-140(251)252)152(262)208-111(54-60-139(249)250)153(263)214-116(71-88(4)5)157(267)222-123(79-134(184)242)162(272)207-106(29-21-63-196-178(187)188)148(258)218-120(75-98-38-46-103(238)47-39-98)160(270)219-119(74-97-36-44-102(237)45-37-97)154(264)202-93(13)145(255)226-127(84-234)165(275)217-115(70-87(2)3)156(266)206-107(30-22-64-197-179(189)190)149(259)221-122(78-101-82-195-86-201-101)161(271)220-121(76-99-40-48-104(239)49-41-99)159(269)215-117(72-89(6)7)158(268)223-124(80-135(185)243)163(273)216-118(73-90(8)9)164(274)228-143(91(10)11)171(281)229-144(96(16)236)172(282)213-113(32-24-66-199-181(193)194)174(284)230(17)129(56-57-133(183)241)167(277)209-108(31-23-65-198-180(191)192)150(260)225-126(177(287)288)77-100-42-50-105(240)51-43-100/h36-51,82,86-96,106-132,142-144,234-240H,18-35,52-81,83-85,182,186H2,1-17H3,(H2,183,241)(H2,184,242)(H2,185,243)(H,195,201)(H,200,276)(H,202,264)(H,203,265)(H,204,257)(H,205,244)(H,206,266)(H,207,272)(H,208,262)(H,209,277)(H,210,278)(H,211,279)(H,212,280)(H,213,282)(H,214,263)(H,215,269)(H,216,273)(H,217,275)(H,218,258)(H,219,270)(H,220,271)(H,221,259)(H,222,267)(H,223,268)(H,224,261)(H,225,260)(H,226,255)(H,227,256)(H,228,274)(H,229,281)(H,245,246)(H,247,248)(H,249,250)(H,251,252)(H,253,254)(H,287,288)(H4,187,188,196)(H4,189,190,197)(H4,191,192,198)(H4,193,194,199)/t92-,93-,94-,95-,96+,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,142-,143-,144-/m0/s1 | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [125I]-PYY(1 to 36 residues) from human Y5R expressed in HEK293 cell membranes after 2 hrs by scintillation proximity assay |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50466536
(CHEMBL4279973)Show SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(C)[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O |r| Show InChI InChI=1S/C181H280N52O55/c1-18-92(12)142(186)170(280)212-114(28-19-20-62-182)175(285)232-68-26-34-131(232)168(278)210-110(53-59-138(247)248)147(257)204-95(15)173(283)231-67-25-33-130(231)166(276)200-83-136(244)205-109(52-58-137(245)246)151(261)224-125(81-141(253)254)155(265)203-94(14)146(256)227-128(85-235)176(286)233-69-27-35-132(233)169(279)211-112(55-61-140(251)252)152(262)208-111(54-60-139(249)250)153(263)214-116(71-88(4)5)157(267)222-123(79-134(184)242)162(272)207-106(29-21-63-196-178(187)188)148(258)218-120(75-98-38-46-103(238)47-39-98)160(270)219-119(74-97-36-44-102(237)45-37-97)154(264)202-93(13)145(255)226-127(84-234)165(275)217-115(70-87(2)3)156(266)206-107(30-22-64-197-179(189)190)149(259)221-122(78-101-82-195-86-201-101)161(271)220-121(76-99-40-48-104(239)49-41-99)159(269)215-117(72-89(6)7)158(268)223-124(80-135(185)243)163(273)216-118(73-90(8)9)164(274)228-143(91(10)11)171(281)229-144(96(16)236)172(282)213-113(32-24-66-199-181(193)194)174(284)230(17)129(56-57-133(183)241)167(277)209-108(31-23-65-198-180(191)192)150(260)225-126(177(287)288)77-100-42-50-105(240)51-43-100/h36-51,82,86-96,106-132,142-144,234-240H,18-35,52-81,83-85,182,186H2,1-17H3,(H2,183,241)(H2,184,242)(H2,185,243)(H,195,201)(H,200,276)(H,202,264)(H,203,265)(H,204,257)(H,205,244)(H,206,266)(H,207,272)(H,208,262)(H,209,277)(H,210,278)(H,211,279)(H,212,280)(H,213,282)(H,214,263)(H,215,269)(H,216,273)(H,217,275)(H,218,258)(H,219,270)(H,220,271)(H,221,259)(H,222,267)(H,223,268)(H,224,261)(H,225,260)(H,226,255)(H,227,256)(H,228,274)(H,229,281)(H,245,246)(H,247,248)(H,249,250)(H,251,252)(H,253,254)(H,287,288)(H4,187,188,196)(H4,189,190,197)(H4,191,192,198)(H4,193,194,199)/t92-,93-,94-,95-,96+,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,142-,143-,144-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.5 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Activation of human Y2R expressed in HEK293 cells assessed as inhibition of isoproterenol-induced increase in intracellular cAMP levels by calcium 5 ... |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 4
(Homo sapiens (Human)) | BDBM50466536
(CHEMBL4279973)Show SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(C)[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O |r| Show InChI InChI=1S/C181H280N52O55/c1-18-92(12)142(186)170(280)212-114(28-19-20-62-182)175(285)232-68-26-34-131(232)168(278)210-110(53-59-138(247)248)147(257)204-95(15)173(283)231-67-25-33-130(231)166(276)200-83-136(244)205-109(52-58-137(245)246)151(261)224-125(81-141(253)254)155(265)203-94(14)146(256)227-128(85-235)176(286)233-69-27-35-132(233)169(279)211-112(55-61-140(251)252)152(262)208-111(54-60-139(249)250)153(263)214-116(71-88(4)5)157(267)222-123(79-134(184)242)162(272)207-106(29-21-63-196-178(187)188)148(258)218-120(75-98-38-46-103(238)47-39-98)160(270)219-119(74-97-36-44-102(237)45-37-97)154(264)202-93(13)145(255)226-127(84-234)165(275)217-115(70-87(2)3)156(266)206-107(30-22-64-197-179(189)190)149(259)221-122(78-101-82-195-86-201-101)161(271)220-121(76-99-40-48-104(239)49-41-99)159(269)215-117(72-89(6)7)158(268)223-124(80-135(185)243)163(273)216-118(73-90(8)9)164(274)228-143(91(10)11)171(281)229-144(96(16)236)172(282)213-113(32-24-66-199-181(193)194)174(284)230(17)129(56-57-133(183)241)167(277)209-108(31-23-65-198-180(191)192)150(260)225-126(177(287)288)77-100-42-50-105(240)51-43-100/h36-51,82,86-96,106-132,142-144,234-240H,18-35,52-81,83-85,182,186H2,1-17H3,(H2,183,241)(H2,184,242)(H2,185,243)(H,195,201)(H,200,276)(H,202,264)(H,203,265)(H,204,257)(H,205,244)(H,206,266)(H,207,272)(H,208,262)(H,209,277)(H,210,278)(H,211,279)(H,212,280)(H,213,282)(H,214,263)(H,215,269)(H,216,273)(H,217,275)(H,218,258)(H,219,270)(H,220,271)(H,221,259)(H,222,267)(H,223,268)(H,224,261)(H,225,260)(H,226,255)(H,227,256)(H,228,274)(H,229,281)(H,245,246)(H,247,248)(H,249,250)(H,251,252)(H,253,254)(H,287,288)(H4,187,188,196)(H4,189,190,197)(H4,191,192,198)(H4,193,194,199)/t92-,93-,94-,95-,96+,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,142-,143-,144-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.501 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Activation of human Y4R expressed in HEK293 cells assessed as inhibition of isoproterenol-induced increase in intracellular cAMP levels by calcium 5 ... |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50466536
(CHEMBL4279973)Show SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(C)[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O |r| Show InChI InChI=1S/C181H280N52O55/c1-18-92(12)142(186)170(280)212-114(28-19-20-62-182)175(285)232-68-26-34-131(232)168(278)210-110(53-59-138(247)248)147(257)204-95(15)173(283)231-67-25-33-130(231)166(276)200-83-136(244)205-109(52-58-137(245)246)151(261)224-125(81-141(253)254)155(265)203-94(14)146(256)227-128(85-235)176(286)233-69-27-35-132(233)169(279)211-112(55-61-140(251)252)152(262)208-111(54-60-139(249)250)153(263)214-116(71-88(4)5)157(267)222-123(79-134(184)242)162(272)207-106(29-21-63-196-178(187)188)148(258)218-120(75-98-38-46-103(238)47-39-98)160(270)219-119(74-97-36-44-102(237)45-37-97)154(264)202-93(13)145(255)226-127(84-234)165(275)217-115(70-87(2)3)156(266)206-107(30-22-64-197-179(189)190)149(259)221-122(78-101-82-195-86-201-101)161(271)220-121(76-99-40-48-104(239)49-41-99)159(269)215-117(72-89(6)7)158(268)223-124(80-135(185)243)163(273)216-118(73-90(8)9)164(274)228-143(91(10)11)171(281)229-144(96(16)236)172(282)213-113(32-24-66-199-181(193)194)174(284)230(17)129(56-57-133(183)241)167(277)209-108(31-23-65-198-180(191)192)150(260)225-126(177(287)288)77-100-42-50-105(240)51-43-100/h36-51,82,86-96,106-132,142-144,234-240H,18-35,52-81,83-85,182,186H2,1-17H3,(H2,183,241)(H2,184,242)(H2,185,243)(H,195,201)(H,200,276)(H,202,264)(H,203,265)(H,204,257)(H,205,244)(H,206,266)(H,207,272)(H,208,262)(H,209,277)(H,210,278)(H,211,279)(H,212,280)(H,213,282)(H,214,263)(H,215,269)(H,216,273)(H,217,275)(H,218,258)(H,219,270)(H,220,271)(H,221,259)(H,222,267)(H,223,268)(H,224,261)(H,225,260)(H,226,255)(H,227,256)(H,228,274)(H,229,281)(H,245,246)(H,247,248)(H,249,250)(H,251,252)(H,253,254)(H,287,288)(H4,187,188,196)(H4,189,190,197)(H4,191,192,198)(H4,193,194,199)/t92-,93-,94-,95-,96+,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,142-,143-,144-/m0/s1 | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 4 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Activation of human Y5R expressed in HEK293 cells assessed as inhibition of isoproterenol-induced increase in intracellular cAMP levels by calcium 5 ... |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 4
(Homo sapiens (Human)) | BDBM50466536
(CHEMBL4279973)Show SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(C)[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O |r| Show InChI InChI=1S/C181H280N52O55/c1-18-92(12)142(186)170(280)212-114(28-19-20-62-182)175(285)232-68-26-34-131(232)168(278)210-110(53-59-138(247)248)147(257)204-95(15)173(283)231-67-25-33-130(231)166(276)200-83-136(244)205-109(52-58-137(245)246)151(261)224-125(81-141(253)254)155(265)203-94(14)146(256)227-128(85-235)176(286)233-69-27-35-132(233)169(279)211-112(55-61-140(251)252)152(262)208-111(54-60-139(249)250)153(263)214-116(71-88(4)5)157(267)222-123(79-134(184)242)162(272)207-106(29-21-63-196-178(187)188)148(258)218-120(75-98-38-46-103(238)47-39-98)160(270)219-119(74-97-36-44-102(237)45-37-97)154(264)202-93(13)145(255)226-127(84-234)165(275)217-115(70-87(2)3)156(266)206-107(30-22-64-197-179(189)190)149(259)221-122(78-101-82-195-86-201-101)161(271)220-121(76-99-40-48-104(239)49-41-99)159(269)215-117(72-89(6)7)158(268)223-124(80-135(185)243)163(273)216-118(73-90(8)9)164(274)228-143(91(10)11)171(281)229-144(96(16)236)172(282)213-113(32-24-66-199-181(193)194)174(284)230(17)129(56-57-133(183)241)167(277)209-108(31-23-65-198-180(191)192)150(260)225-126(177(287)288)77-100-42-50-105(240)51-43-100/h36-51,82,86-96,106-132,142-144,234-240H,18-35,52-81,83-85,182,186H2,1-17H3,(H2,183,241)(H2,184,242)(H2,185,243)(H,195,201)(H,200,276)(H,202,264)(H,203,265)(H,204,257)(H,205,244)(H,206,266)(H,207,272)(H,208,262)(H,209,277)(H,210,278)(H,211,279)(H,212,280)(H,213,282)(H,214,263)(H,215,269)(H,216,273)(H,217,275)(H,218,258)(H,219,270)(H,220,271)(H,221,259)(H,222,267)(H,223,268)(H,224,261)(H,225,260)(H,226,255)(H,227,256)(H,228,274)(H,229,281)(H,245,246)(H,247,248)(H,249,250)(H,251,252)(H,253,254)(H,287,288)(H4,187,188,196)(H4,189,190,197)(H4,191,192,198)(H4,193,194,199)/t92-,93-,94-,95-,96+,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,142-,143-,144-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Activation of human Y4R expressed in HEK293 cells assessed as inhibition of isoproterenol-induced increase in intracellular cAMP levels by calcium 5 ... |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 1
(Homo sapiens (Human)) | BDBM50466536
(CHEMBL4279973)Show SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(C)[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O |r| Show InChI InChI=1S/C181H280N52O55/c1-18-92(12)142(186)170(280)212-114(28-19-20-62-182)175(285)232-68-26-34-131(232)168(278)210-110(53-59-138(247)248)147(257)204-95(15)173(283)231-67-25-33-130(231)166(276)200-83-136(244)205-109(52-58-137(245)246)151(261)224-125(81-141(253)254)155(265)203-94(14)146(256)227-128(85-235)176(286)233-69-27-35-132(233)169(279)211-112(55-61-140(251)252)152(262)208-111(54-60-139(249)250)153(263)214-116(71-88(4)5)157(267)222-123(79-134(184)242)162(272)207-106(29-21-63-196-178(187)188)148(258)218-120(75-98-38-46-103(238)47-39-98)160(270)219-119(74-97-36-44-102(237)45-37-97)154(264)202-93(13)145(255)226-127(84-234)165(275)217-115(70-87(2)3)156(266)206-107(30-22-64-197-179(189)190)149(259)221-122(78-101-82-195-86-201-101)161(271)220-121(76-99-40-48-104(239)49-41-99)159(269)215-117(72-89(6)7)158(268)223-124(80-135(185)243)163(273)216-118(73-90(8)9)164(274)228-143(91(10)11)171(281)229-144(96(16)236)172(282)213-113(32-24-66-199-181(193)194)174(284)230(17)129(56-57-133(183)241)167(277)209-108(31-23-65-198-180(191)192)150(260)225-126(177(287)288)77-100-42-50-105(240)51-43-100/h36-51,82,86-96,106-132,142-144,234-240H,18-35,52-81,83-85,182,186H2,1-17H3,(H2,183,241)(H2,184,242)(H2,185,243)(H,195,201)(H,200,276)(H,202,264)(H,203,265)(H,204,257)(H,205,244)(H,206,266)(H,207,272)(H,208,262)(H,209,277)(H,210,278)(H,211,279)(H,212,280)(H,213,282)(H,214,263)(H,215,269)(H,216,273)(H,217,275)(H,218,258)(H,219,270)(H,220,271)(H,221,259)(H,222,267)(H,223,268)(H,224,261)(H,225,260)(H,226,255)(H,227,256)(H,228,274)(H,229,281)(H,245,246)(H,247,248)(H,249,250)(H,251,252)(H,253,254)(H,287,288)(H4,187,188,196)(H4,189,190,197)(H4,191,192,198)(H4,193,194,199)/t92-,93-,94-,95-,96+,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,142-,143-,144-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Activation of human Y1R expressed in HEK293 cells assessed as inhibition of isoproterenol-induced increase in intracellular cAMP levels by calcium 5 ... |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50466536
(CHEMBL4279973)Show SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(C)[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O |r| Show InChI InChI=1S/C181H280N52O55/c1-18-92(12)142(186)170(280)212-114(28-19-20-62-182)175(285)232-68-26-34-131(232)168(278)210-110(53-59-138(247)248)147(257)204-95(15)173(283)231-67-25-33-130(231)166(276)200-83-136(244)205-109(52-58-137(245)246)151(261)224-125(81-141(253)254)155(265)203-94(14)146(256)227-128(85-235)176(286)233-69-27-35-132(233)169(279)211-112(55-61-140(251)252)152(262)208-111(54-60-139(249)250)153(263)214-116(71-88(4)5)157(267)222-123(79-134(184)242)162(272)207-106(29-21-63-196-178(187)188)148(258)218-120(75-98-38-46-103(238)47-39-98)160(270)219-119(74-97-36-44-102(237)45-37-97)154(264)202-93(13)145(255)226-127(84-234)165(275)217-115(70-87(2)3)156(266)206-107(30-22-64-197-179(189)190)149(259)221-122(78-101-82-195-86-201-101)161(271)220-121(76-99-40-48-104(239)49-41-99)159(269)215-117(72-89(6)7)158(268)223-124(80-135(185)243)163(273)216-118(73-90(8)9)164(274)228-143(91(10)11)171(281)229-144(96(16)236)172(282)213-113(32-24-66-199-181(193)194)174(284)230(17)129(56-57-133(183)241)167(277)209-108(31-23-65-198-180(191)192)150(260)225-126(177(287)288)77-100-42-50-105(240)51-43-100/h36-51,82,86-96,106-132,142-144,234-240H,18-35,52-81,83-85,182,186H2,1-17H3,(H2,183,241)(H2,184,242)(H2,185,243)(H,195,201)(H,200,276)(H,202,264)(H,203,265)(H,204,257)(H,205,244)(H,206,266)(H,207,272)(H,208,262)(H,209,277)(H,210,278)(H,211,279)(H,212,280)(H,213,282)(H,214,263)(H,215,269)(H,216,273)(H,217,275)(H,218,258)(H,219,270)(H,220,271)(H,221,259)(H,222,267)(H,223,268)(H,224,261)(H,225,260)(H,226,255)(H,227,256)(H,228,274)(H,229,281)(H,245,246)(H,247,248)(H,249,250)(H,251,252)(H,253,254)(H,287,288)(H4,187,188,196)(H4,189,190,197)(H4,191,192,198)(H4,193,194,199)/t92-,93-,94-,95-,96+,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,142-,143-,144-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 2.5 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Activation of human Y2R expressed in HEK293 cells assessed as inhibition of isoproterenol-induced increase in intracellular cAMP levels by calcium 5 ... |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 1
(Homo sapiens (Human)) | BDBM50466536
(CHEMBL4279973)Show SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(C)[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O |r| Show InChI InChI=1S/C181H280N52O55/c1-18-92(12)142(186)170(280)212-114(28-19-20-62-182)175(285)232-68-26-34-131(232)168(278)210-110(53-59-138(247)248)147(257)204-95(15)173(283)231-67-25-33-130(231)166(276)200-83-136(244)205-109(52-58-137(245)246)151(261)224-125(81-141(253)254)155(265)203-94(14)146(256)227-128(85-235)176(286)233-69-27-35-132(233)169(279)211-112(55-61-140(251)252)152(262)208-111(54-60-139(249)250)153(263)214-116(71-88(4)5)157(267)222-123(79-134(184)242)162(272)207-106(29-21-63-196-178(187)188)148(258)218-120(75-98-38-46-103(238)47-39-98)160(270)219-119(74-97-36-44-102(237)45-37-97)154(264)202-93(13)145(255)226-127(84-234)165(275)217-115(70-87(2)3)156(266)206-107(30-22-64-197-179(189)190)149(259)221-122(78-101-82-195-86-201-101)161(271)220-121(76-99-40-48-104(239)49-41-99)159(269)215-117(72-89(6)7)158(268)223-124(80-135(185)243)163(273)216-118(73-90(8)9)164(274)228-143(91(10)11)171(281)229-144(96(16)236)172(282)213-113(32-24-66-199-181(193)194)174(284)230(17)129(56-57-133(183)241)167(277)209-108(31-23-65-198-180(191)192)150(260)225-126(177(287)288)77-100-42-50-105(240)51-43-100/h36-51,82,86-96,106-132,142-144,234-240H,18-35,52-81,83-85,182,186H2,1-17H3,(H2,183,241)(H2,184,242)(H2,185,243)(H,195,201)(H,200,276)(H,202,264)(H,203,265)(H,204,257)(H,205,244)(H,206,266)(H,207,272)(H,208,262)(H,209,277)(H,210,278)(H,211,279)(H,212,280)(H,213,282)(H,214,263)(H,215,269)(H,216,273)(H,217,275)(H,218,258)(H,219,270)(H,220,271)(H,221,259)(H,222,267)(H,223,268)(H,224,261)(H,225,260)(H,226,255)(H,227,256)(H,228,274)(H,229,281)(H,245,246)(H,247,248)(H,249,250)(H,251,252)(H,253,254)(H,287,288)(H4,187,188,196)(H4,189,190,197)(H4,191,192,198)(H4,193,194,199)/t92-,93-,94-,95-,96+,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,142-,143-,144-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Activation of human Y1R expressed in HEK293 cells assessed as inhibition of isoproterenol-induced increase in intracellular cAMP levels by calcium 5 ... |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50466536
(CHEMBL4279973)Show SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(C)[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O |r| Show InChI InChI=1S/C181H280N52O55/c1-18-92(12)142(186)170(280)212-114(28-19-20-62-182)175(285)232-68-26-34-131(232)168(278)210-110(53-59-138(247)248)147(257)204-95(15)173(283)231-67-25-33-130(231)166(276)200-83-136(244)205-109(52-58-137(245)246)151(261)224-125(81-141(253)254)155(265)203-94(14)146(256)227-128(85-235)176(286)233-69-27-35-132(233)169(279)211-112(55-61-140(251)252)152(262)208-111(54-60-139(249)250)153(263)214-116(71-88(4)5)157(267)222-123(79-134(184)242)162(272)207-106(29-21-63-196-178(187)188)148(258)218-120(75-98-38-46-103(238)47-39-98)160(270)219-119(74-97-36-44-102(237)45-37-97)154(264)202-93(13)145(255)226-127(84-234)165(275)217-115(70-87(2)3)156(266)206-107(30-22-64-197-179(189)190)149(259)221-122(78-101-82-195-86-201-101)161(271)220-121(76-99-40-48-104(239)49-41-99)159(269)215-117(72-89(6)7)158(268)223-124(80-135(185)243)163(273)216-118(73-90(8)9)164(274)228-143(91(10)11)171(281)229-144(96(16)236)172(282)213-113(32-24-66-199-181(193)194)174(284)230(17)129(56-57-133(183)241)167(277)209-108(31-23-65-198-180(191)192)150(260)225-126(177(287)288)77-100-42-50-105(240)51-43-100/h36-51,82,86-96,106-132,142-144,234-240H,18-35,52-81,83-85,182,186H2,1-17H3,(H2,183,241)(H2,184,242)(H2,185,243)(H,195,201)(H,200,276)(H,202,264)(H,203,265)(H,204,257)(H,205,244)(H,206,266)(H,207,272)(H,208,262)(H,209,277)(H,210,278)(H,211,279)(H,212,280)(H,213,282)(H,214,263)(H,215,269)(H,216,273)(H,217,275)(H,218,258)(H,219,270)(H,220,271)(H,221,259)(H,222,267)(H,223,268)(H,224,261)(H,225,260)(H,226,255)(H,227,256)(H,228,274)(H,229,281)(H,245,246)(H,247,248)(H,249,250)(H,251,252)(H,253,254)(H,287,288)(H4,187,188,196)(H4,189,190,197)(H4,191,192,198)(H4,193,194,199)/t92-,93-,94-,95-,96+,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,142-,143-,144-/m0/s1 | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 4 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Activation of human Y5R expressed in HEK293 cells assessed as inhibition of isoproterenol-induced increase in intracellular cAMP levels by calcium 5 ... |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |