Found 8 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Neuropeptide Y receptor type 4
(Homo sapiens (Human)) | BDBM50466545
(CHEMBL4280898)Show SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CC(O)=O)Cc1ccc(O)cc1 |r| Show InChI InChI=1S/C180H278N52O55/c1-17-92(12)142(185)170(281)213-115(27-18-19-61-181)175(286)231-67-25-33-130(231)168(279)209-111(53-58-137(246)247)147(258)203-95(15)173(284)230-66-24-32-129(230)167(278)199-81-135(243)204-109(52-57-136(244)245)151(262)224-126(79-140(252)253)156(267)202-94(14)146(257)226-128(85-234)176(287)232-68-26-34-131(232)169(280)210-113(55-60-139(250)251)152(263)208-112(54-59-138(248)249)154(265)214-117(70-88(4)5)158(269)222-124(77-133(183)241)163(274)206-106(28-20-62-195-177(186)187)149(260)218-121(74-98-37-45-103(237)46-38-98)161(272)219-120(73-97-35-43-102(236)44-36-97)155(266)201-93(13)145(256)225-127(84-233)166(277)217-116(69-87(2)3)157(268)205-107(29-21-63-196-178(188)189)150(261)221-123(76-101-80-194-86-200-101)162(273)220-122(75-99-39-47-104(238)48-40-99)160(271)215-118(71-89(6)7)159(270)223-125(78-134(184)242)164(275)216-119(72-90(8)9)165(276)227-143(91(10)11)171(282)228-144(96(16)235)172(283)211-108(30-22-64-197-179(190)191)148(259)207-110(51-56-132(182)240)153(264)212-114(31-23-65-198-180(192)193)174(285)229(83-141(254)255)82-100-41-49-105(239)50-42-100/h35-50,80,86-96,106-131,142-144,233-239H,17-34,51-79,81-85,181,185H2,1-16H3,(H2,182,240)(H2,183,241)(H2,184,242)(H,194,200)(H,199,278)(H,201,266)(H,202,267)(H,203,258)(H,204,243)(H,205,268)(H,206,274)(H,207,259)(H,208,263)(H,209,279)(H,210,280)(H,211,283)(H,212,264)(H,213,281)(H,214,265)(H,215,271)(H,216,275)(H,217,277)(H,218,260)(H,219,272)(H,220,273)(H,221,261)(H,222,269)(H,223,270)(H,224,262)(H,225,256)(H,226,257)(H,227,276)(H,228,282)(H,244,245)(H,246,247)(H,248,249)(H,250,251)(H,252,253)(H,254,255)(H4,186,187,195)(H4,188,189,196)(H4,190,191,197)(H4,192,193,198)/t92-,93-,94-,95-,96+,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,142-,143-,144-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| 630 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [125I]-PP from human Y4R expressed in CHO-K1 cell membranes after 2 hrs by scintillation proximity assay |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 4
(Homo sapiens (Human)) | BDBM50466545
(CHEMBL4280898)Show SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CC(O)=O)Cc1ccc(O)cc1 |r| Show InChI InChI=1S/C180H278N52O55/c1-17-92(12)142(185)170(281)213-115(27-18-19-61-181)175(286)231-67-25-33-130(231)168(279)209-111(53-58-137(246)247)147(258)203-95(15)173(284)230-66-24-32-129(230)167(278)199-81-135(243)204-109(52-57-136(244)245)151(262)224-126(79-140(252)253)156(267)202-94(14)146(257)226-128(85-234)176(287)232-68-26-34-131(232)169(280)210-113(55-60-139(250)251)152(263)208-112(54-59-138(248)249)154(265)214-117(70-88(4)5)158(269)222-124(77-133(183)241)163(274)206-106(28-20-62-195-177(186)187)149(260)218-121(74-98-37-45-103(237)46-38-98)161(272)219-120(73-97-35-43-102(236)44-36-97)155(266)201-93(13)145(256)225-127(84-233)166(277)217-116(69-87(2)3)157(268)205-107(29-21-63-196-178(188)189)150(261)221-123(76-101-80-194-86-200-101)162(273)220-122(75-99-39-47-104(238)48-40-99)160(271)215-118(71-89(6)7)159(270)223-125(78-134(184)242)164(275)216-119(72-90(8)9)165(276)227-143(91(10)11)171(282)228-144(96(16)235)172(283)211-108(30-22-64-197-179(190)191)148(259)207-110(51-56-132(182)240)153(264)212-114(31-23-65-198-180(192)193)174(285)229(83-141(254)255)82-100-41-49-105(239)50-42-100/h35-50,80,86-96,106-131,142-144,233-239H,17-34,51-79,81-85,181,185H2,1-16H3,(H2,182,240)(H2,183,241)(H2,184,242)(H,194,200)(H,199,278)(H,201,266)(H,202,267)(H,203,258)(H,204,243)(H,205,268)(H,206,274)(H,207,259)(H,208,263)(H,209,279)(H,210,280)(H,211,283)(H,212,264)(H,213,281)(H,214,265)(H,215,271)(H,216,275)(H,217,277)(H,218,260)(H,219,272)(H,220,273)(H,221,261)(H,222,269)(H,223,270)(H,224,262)(H,225,256)(H,226,257)(H,227,276)(H,228,282)(H,244,245)(H,246,247)(H,248,249)(H,250,251)(H,252,253)(H,254,255)(H4,186,187,195)(H4,188,189,196)(H4,190,191,197)(H4,192,193,198)/t92-,93-,94-,95-,96+,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,142-,143-,144-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 631 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [125I]-PP from human Y4R expressed in CHO-K1 cell membranes after 2 hrs by scintillation proximity assay |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50466545
(CHEMBL4280898)Show SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CC(O)=O)Cc1ccc(O)cc1 |r| Show InChI InChI=1S/C180H278N52O55/c1-17-92(12)142(185)170(281)213-115(27-18-19-61-181)175(286)231-67-25-33-130(231)168(279)209-111(53-58-137(246)247)147(258)203-95(15)173(284)230-66-24-32-129(230)167(278)199-81-135(243)204-109(52-57-136(244)245)151(262)224-126(79-140(252)253)156(267)202-94(14)146(257)226-128(85-234)176(287)232-68-26-34-131(232)169(280)210-113(55-60-139(250)251)152(263)208-112(54-59-138(248)249)154(265)214-117(70-88(4)5)158(269)222-124(77-133(183)241)163(274)206-106(28-20-62-195-177(186)187)149(260)218-121(74-98-37-45-103(237)46-38-98)161(272)219-120(73-97-35-43-102(236)44-36-97)155(266)201-93(13)145(256)225-127(84-233)166(277)217-116(69-87(2)3)157(268)205-107(29-21-63-196-178(188)189)150(261)221-123(76-101-80-194-86-200-101)162(273)220-122(75-99-39-47-104(238)48-40-99)160(271)215-118(71-89(6)7)159(270)223-125(78-134(184)242)164(275)216-119(72-90(8)9)165(276)227-143(91(10)11)171(282)228-144(96(16)235)172(283)211-108(30-22-64-197-179(190)191)148(259)207-110(51-56-132(182)240)153(264)212-114(31-23-65-198-180(192)193)174(285)229(83-141(254)255)82-100-41-49-105(239)50-42-100/h35-50,80,86-96,106-131,142-144,233-239H,17-34,51-79,81-85,181,185H2,1-16H3,(H2,182,240)(H2,183,241)(H2,184,242)(H,194,200)(H,199,278)(H,201,266)(H,202,267)(H,203,258)(H,204,243)(H,205,268)(H,206,274)(H,207,259)(H,208,263)(H,209,279)(H,210,280)(H,211,283)(H,212,264)(H,213,281)(H,214,265)(H,215,271)(H,216,275)(H,217,277)(H,218,260)(H,219,272)(H,220,273)(H,221,261)(H,222,269)(H,223,270)(H,224,262)(H,225,256)(H,226,257)(H,227,276)(H,228,282)(H,244,245)(H,246,247)(H,248,249)(H,250,251)(H,252,253)(H,254,255)(H4,186,187,195)(H4,188,189,196)(H4,190,191,197)(H4,192,193,198)/t92-,93-,94-,95-,96+,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,142-,143-,144-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 1.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [125I]-PYY(1 to 36 residues) from human Y2R expressed in CHO cell membranes after 2 hrs by scintillation proximity assay |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50466545
(CHEMBL4280898)Show SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CC(O)=O)Cc1ccc(O)cc1 |r| Show InChI InChI=1S/C180H278N52O55/c1-17-92(12)142(185)170(281)213-115(27-18-19-61-181)175(286)231-67-25-33-130(231)168(279)209-111(53-58-137(246)247)147(258)203-95(15)173(284)230-66-24-32-129(230)167(278)199-81-135(243)204-109(52-57-136(244)245)151(262)224-126(79-140(252)253)156(267)202-94(14)146(257)226-128(85-234)176(287)232-68-26-34-131(232)169(280)210-113(55-60-139(250)251)152(263)208-112(54-59-138(248)249)154(265)214-117(70-88(4)5)158(269)222-124(77-133(183)241)163(274)206-106(28-20-62-195-177(186)187)149(260)218-121(74-98-37-45-103(237)46-38-98)161(272)219-120(73-97-35-43-102(236)44-36-97)155(266)201-93(13)145(256)225-127(84-233)166(277)217-116(69-87(2)3)157(268)205-107(29-21-63-196-178(188)189)150(261)221-123(76-101-80-194-86-200-101)162(273)220-122(75-99-39-47-104(238)48-40-99)160(271)215-118(71-89(6)7)159(270)223-125(78-134(184)242)164(275)216-119(72-90(8)9)165(276)227-143(91(10)11)171(282)228-144(96(16)235)172(283)211-108(30-22-64-197-179(190)191)148(259)207-110(51-56-132(182)240)153(264)212-114(31-23-65-198-180(192)193)174(285)229(83-141(254)255)82-100-41-49-105(239)50-42-100/h35-50,80,86-96,106-131,142-144,233-239H,17-34,51-79,81-85,181,185H2,1-16H3,(H2,182,240)(H2,183,241)(H2,184,242)(H,194,200)(H,199,278)(H,201,266)(H,202,267)(H,203,258)(H,204,243)(H,205,268)(H,206,274)(H,207,259)(H,208,263)(H,209,279)(H,210,280)(H,211,283)(H,212,264)(H,213,281)(H,214,265)(H,215,271)(H,216,275)(H,217,277)(H,218,260)(H,219,272)(H,220,273)(H,221,261)(H,222,269)(H,223,270)(H,224,262)(H,225,256)(H,226,257)(H,227,276)(H,228,282)(H,244,245)(H,246,247)(H,248,249)(H,250,251)(H,252,253)(H,254,255)(H4,186,187,195)(H4,188,189,196)(H4,190,191,197)(H4,192,193,198)/t92-,93-,94-,95-,96+,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,142-,143-,144-/m0/s1 | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 1.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [125I]-PYY(1 to 36 residues) from human Y5R expressed in HEK293 cell membranes after 2 hrs by scintillation proximity assay |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50466545
(CHEMBL4280898)Show SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CC(O)=O)Cc1ccc(O)cc1 |r| Show InChI InChI=1S/C180H278N52O55/c1-17-92(12)142(185)170(281)213-115(27-18-19-61-181)175(286)231-67-25-33-130(231)168(279)209-111(53-58-137(246)247)147(258)203-95(15)173(284)230-66-24-32-129(230)167(278)199-81-135(243)204-109(52-57-136(244)245)151(262)224-126(79-140(252)253)156(267)202-94(14)146(257)226-128(85-234)176(287)232-68-26-34-131(232)169(280)210-113(55-60-139(250)251)152(263)208-112(54-59-138(248)249)154(265)214-117(70-88(4)5)158(269)222-124(77-133(183)241)163(274)206-106(28-20-62-195-177(186)187)149(260)218-121(74-98-37-45-103(237)46-38-98)161(272)219-120(73-97-35-43-102(236)44-36-97)155(266)201-93(13)145(256)225-127(84-233)166(277)217-116(69-87(2)3)157(268)205-107(29-21-63-196-178(188)189)150(261)221-123(76-101-80-194-86-200-101)162(273)220-122(75-99-39-47-104(238)48-40-99)160(271)215-118(71-89(6)7)159(270)223-125(78-134(184)242)164(275)216-119(72-90(8)9)165(276)227-143(91(10)11)171(282)228-144(96(16)235)172(283)211-108(30-22-64-197-179(190)191)148(259)207-110(51-56-132(182)240)153(264)212-114(31-23-65-198-180(192)193)174(285)229(83-141(254)255)82-100-41-49-105(239)50-42-100/h35-50,80,86-96,106-131,142-144,233-239H,17-34,51-79,81-85,181,185H2,1-16H3,(H2,182,240)(H2,183,241)(H2,184,242)(H,194,200)(H,199,278)(H,201,266)(H,202,267)(H,203,258)(H,204,243)(H,205,268)(H,206,274)(H,207,259)(H,208,263)(H,209,279)(H,210,280)(H,211,283)(H,212,264)(H,213,281)(H,214,265)(H,215,271)(H,216,275)(H,217,277)(H,218,260)(H,219,272)(H,220,273)(H,221,261)(H,222,269)(H,223,270)(H,224,262)(H,225,256)(H,226,257)(H,227,276)(H,228,282)(H,244,245)(H,246,247)(H,248,249)(H,250,251)(H,252,253)(H,254,255)(H4,186,187,195)(H4,188,189,196)(H4,190,191,197)(H4,192,193,198)/t92-,93-,94-,95-,96+,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,142-,143-,144-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [125I]-PYY(1 to 36 residues) from human Y2R expressed in CHO cell membranes after 2 hrs by scintillation proximity assay |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50466545
(CHEMBL4280898)Show SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CC(O)=O)Cc1ccc(O)cc1 |r| Show InChI InChI=1S/C180H278N52O55/c1-17-92(12)142(185)170(281)213-115(27-18-19-61-181)175(286)231-67-25-33-130(231)168(279)209-111(53-58-137(246)247)147(258)203-95(15)173(284)230-66-24-32-129(230)167(278)199-81-135(243)204-109(52-57-136(244)245)151(262)224-126(79-140(252)253)156(267)202-94(14)146(257)226-128(85-234)176(287)232-68-26-34-131(232)169(280)210-113(55-60-139(250)251)152(263)208-112(54-59-138(248)249)154(265)214-117(70-88(4)5)158(269)222-124(77-133(183)241)163(274)206-106(28-20-62-195-177(186)187)149(260)218-121(74-98-37-45-103(237)46-38-98)161(272)219-120(73-97-35-43-102(236)44-36-97)155(266)201-93(13)145(256)225-127(84-233)166(277)217-116(69-87(2)3)157(268)205-107(29-21-63-196-178(188)189)150(261)221-123(76-101-80-194-86-200-101)162(273)220-122(75-99-39-47-104(238)48-40-99)160(271)215-118(71-89(6)7)159(270)223-125(78-134(184)242)164(275)216-119(72-90(8)9)165(276)227-143(91(10)11)171(282)228-144(96(16)235)172(283)211-108(30-22-64-197-179(190)191)148(259)207-110(51-56-132(182)240)153(264)212-114(31-23-65-198-180(192)193)174(285)229(83-141(254)255)82-100-41-49-105(239)50-42-100/h35-50,80,86-96,106-131,142-144,233-239H,17-34,51-79,81-85,181,185H2,1-16H3,(H2,182,240)(H2,183,241)(H2,184,242)(H,194,200)(H,199,278)(H,201,266)(H,202,267)(H,203,258)(H,204,243)(H,205,268)(H,206,274)(H,207,259)(H,208,263)(H,209,279)(H,210,280)(H,211,283)(H,212,264)(H,213,281)(H,214,265)(H,215,271)(H,216,275)(H,217,277)(H,218,260)(H,219,272)(H,220,273)(H,221,261)(H,222,269)(H,223,270)(H,224,262)(H,225,256)(H,226,257)(H,227,276)(H,228,282)(H,244,245)(H,246,247)(H,248,249)(H,250,251)(H,252,253)(H,254,255)(H4,186,187,195)(H4,188,189,196)(H4,190,191,197)(H4,192,193,198)/t92-,93-,94-,95-,96+,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,142-,143-,144-/m0/s1 | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [125I]-PYY(1 to 36 residues) from human Y5R expressed in HEK293 cell membranes after 2 hrs by scintillation proximity assay |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 1
(Homo sapiens (Human)) | BDBM50466545
(CHEMBL4280898)Show SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CC(O)=O)Cc1ccc(O)cc1 |r| Show InChI InChI=1S/C180H278N52O55/c1-17-92(12)142(185)170(281)213-115(27-18-19-61-181)175(286)231-67-25-33-130(231)168(279)209-111(53-58-137(246)247)147(258)203-95(15)173(284)230-66-24-32-129(230)167(278)199-81-135(243)204-109(52-57-136(244)245)151(262)224-126(79-140(252)253)156(267)202-94(14)146(257)226-128(85-234)176(287)232-68-26-34-131(232)169(280)210-113(55-60-139(250)251)152(263)208-112(54-59-138(248)249)154(265)214-117(70-88(4)5)158(269)222-124(77-133(183)241)163(274)206-106(28-20-62-195-177(186)187)149(260)218-121(74-98-37-45-103(237)46-38-98)161(272)219-120(73-97-35-43-102(236)44-36-97)155(266)201-93(13)145(256)225-127(84-233)166(277)217-116(69-87(2)3)157(268)205-107(29-21-63-196-178(188)189)150(261)221-123(76-101-80-194-86-200-101)162(273)220-122(75-99-39-47-104(238)48-40-99)160(271)215-118(71-89(6)7)159(270)223-125(78-134(184)242)164(275)216-119(72-90(8)9)165(276)227-143(91(10)11)171(282)228-144(96(16)235)172(283)211-108(30-22-64-197-179(190)191)148(259)207-110(51-56-132(182)240)153(264)212-114(31-23-65-198-180(192)193)174(285)229(83-141(254)255)82-100-41-49-105(239)50-42-100/h35-50,80,86-96,106-131,142-144,233-239H,17-34,51-79,81-85,181,185H2,1-16H3,(H2,182,240)(H2,183,241)(H2,184,242)(H,194,200)(H,199,278)(H,201,266)(H,202,267)(H,203,258)(H,204,243)(H,205,268)(H,206,274)(H,207,259)(H,208,263)(H,209,279)(H,210,280)(H,211,283)(H,212,264)(H,213,281)(H,214,265)(H,215,271)(H,216,275)(H,217,277)(H,218,260)(H,219,272)(H,220,273)(H,221,261)(H,222,269)(H,223,270)(H,224,262)(H,225,256)(H,226,257)(H,227,276)(H,228,282)(H,244,245)(H,246,247)(H,248,249)(H,250,251)(H,252,253)(H,254,255)(H4,186,187,195)(H4,188,189,196)(H4,190,191,197)(H4,192,193,198)/t92-,93-,94-,95-,96+,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,142-,143-,144-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [125I]-PYY(1 to 36 residues) from human Y1R expressed in BHK-21 cell membranes after 2 hrs by scintillation proximity assay |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 1
(Homo sapiens (Human)) | BDBM50466545
(CHEMBL4280898)Show SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(CC(O)=O)Cc1ccc(O)cc1 |r| Show InChI InChI=1S/C180H278N52O55/c1-17-92(12)142(185)170(281)213-115(27-18-19-61-181)175(286)231-67-25-33-130(231)168(279)209-111(53-58-137(246)247)147(258)203-95(15)173(284)230-66-24-32-129(230)167(278)199-81-135(243)204-109(52-57-136(244)245)151(262)224-126(79-140(252)253)156(267)202-94(14)146(257)226-128(85-234)176(287)232-68-26-34-131(232)169(280)210-113(55-60-139(250)251)152(263)208-112(54-59-138(248)249)154(265)214-117(70-88(4)5)158(269)222-124(77-133(183)241)163(274)206-106(28-20-62-195-177(186)187)149(260)218-121(74-98-37-45-103(237)46-38-98)161(272)219-120(73-97-35-43-102(236)44-36-97)155(266)201-93(13)145(256)225-127(84-233)166(277)217-116(69-87(2)3)157(268)205-107(29-21-63-196-178(188)189)150(261)221-123(76-101-80-194-86-200-101)162(273)220-122(75-99-39-47-104(238)48-40-99)160(271)215-118(71-89(6)7)159(270)223-125(78-134(184)242)164(275)216-119(72-90(8)9)165(276)227-143(91(10)11)171(282)228-144(96(16)235)172(283)211-108(30-22-64-197-179(190)191)148(259)207-110(51-56-132(182)240)153(264)212-114(31-23-65-198-180(192)193)174(285)229(83-141(254)255)82-100-41-49-105(239)50-42-100/h35-50,80,86-96,106-131,142-144,233-239H,17-34,51-79,81-85,181,185H2,1-16H3,(H2,182,240)(H2,183,241)(H2,184,242)(H,194,200)(H,199,278)(H,201,266)(H,202,267)(H,203,258)(H,204,243)(H,205,268)(H,206,274)(H,207,259)(H,208,263)(H,209,279)(H,210,280)(H,211,283)(H,212,264)(H,213,281)(H,214,265)(H,215,271)(H,216,275)(H,217,277)(H,218,260)(H,219,272)(H,220,273)(H,221,261)(H,222,269)(H,223,270)(H,224,262)(H,225,256)(H,226,257)(H,227,276)(H,228,282)(H,244,245)(H,246,247)(H,248,249)(H,250,251)(H,252,253)(H,254,255)(H4,186,187,195)(H4,188,189,196)(H4,190,191,197)(H4,192,193,198)/t92-,93-,94-,95-,96+,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,142-,143-,144-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [125I]-PYY(1 to 36 residues) from human Y1R expressed in BHK-21 cell membranes after 2 hrs by scintillation proximity assay |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |