Found 16 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50466525
(CHEMBL4285633)Show SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCNC(N)=N)CC(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O |r| Show InChI InChI=1S/C180H278N52O55/c1-17-91(12)142(185)170(280)214-114(26-18-19-60-181)174(284)231-66-24-31-130(231)168(278)211-111(51-56-138(247)248)147(257)203-94(15)173(283)230-65-23-30-129(230)167(277)199-82-136(244)205-109(50-55-137(245)246)152(262)225-125(80-141(253)254)156(266)202-93(14)146(256)227-128(84-234)175(285)232-67-25-32-131(232)169(279)212-113(53-58-140(251)252)153(263)210-112(52-57-139(249)250)154(264)215-116(69-87(4)5)158(268)223-123(78-133(183)241)163(273)208-106(27-20-61-195-177(186)187)150(260)219-120(73-97-35-43-103(237)44-36-97)161(271)220-119(72-96-33-41-102(236)42-34-96)155(265)201-92(13)145(255)226-127(83-233)166(276)218-115(68-86(2)3)157(267)207-107(28-21-62-196-178(188)189)151(261)222-122(76-101-81-194-85-200-101)162(272)221-121(74-98-37-45-104(238)46-38-98)160(270)216-117(70-88(6)7)159(269)224-124(79-134(184)242)164(274)217-118(71-89(8)9)165(275)228-143(90(10)11)171(281)229-144(95(16)235)172(282)213-108(29-22-63-197-179(190)191)149(259)209-110(49-54-132(182)240)148(258)204-100(59-64-198-180(192)193)77-135(243)206-126(176(286)287)75-99-39-47-105(239)48-40-99/h33-48,81,85-95,100,106-131,142-144,233-239H,17-32,49-80,82-84,181,185H2,1-16H3,(H2,182,240)(H2,183,241)(H2,184,242)(H,194,200)(H,199,277)(H,201,265)(H,202,266)(H,203,257)(H,204,258)(H,205,244)(H,206,243)(H,207,267)(H,208,273)(H,209,259)(H,210,263)(H,211,278)(H,212,279)(H,213,282)(H,214,280)(H,215,264)(H,216,270)(H,217,274)(H,218,276)(H,219,260)(H,220,271)(H,221,272)(H,222,261)(H,223,268)(H,224,269)(H,225,262)(H,226,255)(H,227,256)(H,228,275)(H,229,281)(H,245,246)(H,247,248)(H,249,250)(H,251,252)(H,253,254)(H,286,287)(H4,186,187,195)(H4,188,189,196)(H4,190,191,197)(H4,192,193,198)/t91-,92-,93-,94-,95+,100-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,142-,143-,144-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| 2.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [125I]-PYY(1 to 36 residues) from human Y2R expressed in CHO cell membranes after 2 hrs by scintillation proximity assay |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50466525
(CHEMBL4285633)Show SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCNC(N)=N)CC(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O |r| Show InChI InChI=1S/C180H278N52O55/c1-17-91(12)142(185)170(280)214-114(26-18-19-60-181)174(284)231-66-24-31-130(231)168(278)211-111(51-56-138(247)248)147(257)203-94(15)173(283)230-65-23-30-129(230)167(277)199-82-136(244)205-109(50-55-137(245)246)152(262)225-125(80-141(253)254)156(266)202-93(14)146(256)227-128(84-234)175(285)232-67-25-32-131(232)169(279)212-113(53-58-140(251)252)153(263)210-112(52-57-139(249)250)154(264)215-116(69-87(4)5)158(268)223-123(78-133(183)241)163(273)208-106(27-20-61-195-177(186)187)150(260)219-120(73-97-35-43-103(237)44-36-97)161(271)220-119(72-96-33-41-102(236)42-34-96)155(265)201-92(13)145(255)226-127(83-233)166(276)218-115(68-86(2)3)157(267)207-107(28-21-62-196-178(188)189)151(261)222-122(76-101-81-194-85-200-101)162(272)221-121(74-98-37-45-104(238)46-38-98)160(270)216-117(70-88(6)7)159(269)224-124(79-134(184)242)164(274)217-118(71-89(8)9)165(275)228-143(90(10)11)171(281)229-144(95(16)235)172(282)213-108(29-22-63-197-179(190)191)149(259)209-110(49-54-132(182)240)148(258)204-100(59-64-198-180(192)193)77-135(243)206-126(176(286)287)75-99-39-47-105(239)48-40-99/h33-48,81,85-95,100,106-131,142-144,233-239H,17-32,49-80,82-84,181,185H2,1-16H3,(H2,182,240)(H2,183,241)(H2,184,242)(H,194,200)(H,199,277)(H,201,265)(H,202,266)(H,203,257)(H,204,258)(H,205,244)(H,206,243)(H,207,267)(H,208,273)(H,209,259)(H,210,263)(H,211,278)(H,212,279)(H,213,282)(H,214,280)(H,215,264)(H,216,270)(H,217,274)(H,218,276)(H,219,260)(H,220,271)(H,221,272)(H,222,261)(H,223,268)(H,224,269)(H,225,262)(H,226,255)(H,227,256)(H,228,275)(H,229,281)(H,245,246)(H,247,248)(H,249,250)(H,251,252)(H,253,254)(H,286,287)(H4,186,187,195)(H4,188,189,196)(H4,190,191,197)(H4,192,193,198)/t91-,92-,93-,94-,95+,100-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,142-,143-,144-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 2.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [125I]-PYY(1 to 36 residues) from human Y2R expressed in CHO cell membranes after 2 hrs by scintillation proximity assay |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50466525
(CHEMBL4285633)Show SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCNC(N)=N)CC(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O |r| Show InChI InChI=1S/C180H278N52O55/c1-17-91(12)142(185)170(280)214-114(26-18-19-60-181)174(284)231-66-24-31-130(231)168(278)211-111(51-56-138(247)248)147(257)203-94(15)173(283)230-65-23-30-129(230)167(277)199-82-136(244)205-109(50-55-137(245)246)152(262)225-125(80-141(253)254)156(266)202-93(14)146(256)227-128(84-234)175(285)232-67-25-32-131(232)169(279)212-113(53-58-140(251)252)153(263)210-112(52-57-139(249)250)154(264)215-116(69-87(4)5)158(268)223-123(78-133(183)241)163(273)208-106(27-20-61-195-177(186)187)150(260)219-120(73-97-35-43-103(237)44-36-97)161(271)220-119(72-96-33-41-102(236)42-34-96)155(265)201-92(13)145(255)226-127(83-233)166(276)218-115(68-86(2)3)157(267)207-107(28-21-62-196-178(188)189)151(261)222-122(76-101-81-194-85-200-101)162(272)221-121(74-98-37-45-104(238)46-38-98)160(270)216-117(70-88(6)7)159(269)224-124(79-134(184)242)164(274)217-118(71-89(8)9)165(275)228-143(90(10)11)171(281)229-144(95(16)235)172(282)213-108(29-22-63-197-179(190)191)149(259)209-110(49-54-132(182)240)148(258)204-100(59-64-198-180(192)193)77-135(243)206-126(176(286)287)75-99-39-47-105(239)48-40-99/h33-48,81,85-95,100,106-131,142-144,233-239H,17-32,49-80,82-84,181,185H2,1-16H3,(H2,182,240)(H2,183,241)(H2,184,242)(H,194,200)(H,199,277)(H,201,265)(H,202,266)(H,203,257)(H,204,258)(H,205,244)(H,206,243)(H,207,267)(H,208,273)(H,209,259)(H,210,263)(H,211,278)(H,212,279)(H,213,282)(H,214,280)(H,215,264)(H,216,270)(H,217,274)(H,218,276)(H,219,260)(H,220,271)(H,221,272)(H,222,261)(H,223,268)(H,224,269)(H,225,262)(H,226,255)(H,227,256)(H,228,275)(H,229,281)(H,245,246)(H,247,248)(H,249,250)(H,251,252)(H,253,254)(H,286,287)(H4,186,187,195)(H4,188,189,196)(H4,190,191,197)(H4,192,193,198)/t91-,92-,93-,94-,95+,100-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,142-,143-,144-/m0/s1 | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [125I]-PYY(1 to 36 residues) from human Y5R expressed in HEK293 cell membranes after 2 hrs by scintillation proximity assay |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50466525
(CHEMBL4285633)Show SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCNC(N)=N)CC(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O |r| Show InChI InChI=1S/C180H278N52O55/c1-17-91(12)142(185)170(280)214-114(26-18-19-60-181)174(284)231-66-24-31-130(231)168(278)211-111(51-56-138(247)248)147(257)203-94(15)173(283)230-65-23-30-129(230)167(277)199-82-136(244)205-109(50-55-137(245)246)152(262)225-125(80-141(253)254)156(266)202-93(14)146(256)227-128(84-234)175(285)232-67-25-32-131(232)169(279)212-113(53-58-140(251)252)153(263)210-112(52-57-139(249)250)154(264)215-116(69-87(4)5)158(268)223-123(78-133(183)241)163(273)208-106(27-20-61-195-177(186)187)150(260)219-120(73-97-35-43-103(237)44-36-97)161(271)220-119(72-96-33-41-102(236)42-34-96)155(265)201-92(13)145(255)226-127(83-233)166(276)218-115(68-86(2)3)157(267)207-107(28-21-62-196-178(188)189)151(261)222-122(76-101-81-194-85-200-101)162(272)221-121(74-98-37-45-104(238)46-38-98)160(270)216-117(70-88(6)7)159(269)224-124(79-134(184)242)164(274)217-118(71-89(8)9)165(275)228-143(90(10)11)171(281)229-144(95(16)235)172(282)213-108(29-22-63-197-179(190)191)149(259)209-110(49-54-132(182)240)148(258)204-100(59-64-198-180(192)193)77-135(243)206-126(176(286)287)75-99-39-47-105(239)48-40-99/h33-48,81,85-95,100,106-131,142-144,233-239H,17-32,49-80,82-84,181,185H2,1-16H3,(H2,182,240)(H2,183,241)(H2,184,242)(H,194,200)(H,199,277)(H,201,265)(H,202,266)(H,203,257)(H,204,258)(H,205,244)(H,206,243)(H,207,267)(H,208,273)(H,209,259)(H,210,263)(H,211,278)(H,212,279)(H,213,282)(H,214,280)(H,215,264)(H,216,270)(H,217,274)(H,218,276)(H,219,260)(H,220,271)(H,221,272)(H,222,261)(H,223,268)(H,224,269)(H,225,262)(H,226,255)(H,227,256)(H,228,275)(H,229,281)(H,245,246)(H,247,248)(H,249,250)(H,251,252)(H,253,254)(H,286,287)(H4,186,187,195)(H4,188,189,196)(H4,190,191,197)(H4,192,193,198)/t91-,92-,93-,94-,95+,100-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,142-,143-,144-/m0/s1 | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [125I]-PYY(1 to 36 residues) from human Y5R expressed in HEK293 cell membranes after 2 hrs by scintillation proximity assay |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 4
(Homo sapiens (Human)) | BDBM50466525
(CHEMBL4285633)Show SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCNC(N)=N)CC(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O |r| Show InChI InChI=1S/C180H278N52O55/c1-17-91(12)142(185)170(280)214-114(26-18-19-60-181)174(284)231-66-24-31-130(231)168(278)211-111(51-56-138(247)248)147(257)203-94(15)173(283)230-65-23-30-129(230)167(277)199-82-136(244)205-109(50-55-137(245)246)152(262)225-125(80-141(253)254)156(266)202-93(14)146(256)227-128(84-234)175(285)232-67-25-32-131(232)169(279)212-113(53-58-140(251)252)153(263)210-112(52-57-139(249)250)154(264)215-116(69-87(4)5)158(268)223-123(78-133(183)241)163(273)208-106(27-20-61-195-177(186)187)150(260)219-120(73-97-35-43-103(237)44-36-97)161(271)220-119(72-96-33-41-102(236)42-34-96)155(265)201-92(13)145(255)226-127(83-233)166(276)218-115(68-86(2)3)157(267)207-107(28-21-62-196-178(188)189)151(261)222-122(76-101-81-194-85-200-101)162(272)221-121(74-98-37-45-104(238)46-38-98)160(270)216-117(70-88(6)7)159(269)224-124(79-134(184)242)164(274)217-118(71-89(8)9)165(275)228-143(90(10)11)171(281)229-144(95(16)235)172(282)213-108(29-22-63-197-179(190)191)149(259)209-110(49-54-132(182)240)148(258)204-100(59-64-198-180(192)193)77-135(243)206-126(176(286)287)75-99-39-47-105(239)48-40-99/h33-48,81,85-95,100,106-131,142-144,233-239H,17-32,49-80,82-84,181,185H2,1-16H3,(H2,182,240)(H2,183,241)(H2,184,242)(H,194,200)(H,199,277)(H,201,265)(H,202,266)(H,203,257)(H,204,258)(H,205,244)(H,206,243)(H,207,267)(H,208,273)(H,209,259)(H,210,263)(H,211,278)(H,212,279)(H,213,282)(H,214,280)(H,215,264)(H,216,270)(H,217,274)(H,218,276)(H,219,260)(H,220,271)(H,221,272)(H,222,261)(H,223,268)(H,224,269)(H,225,262)(H,226,255)(H,227,256)(H,228,275)(H,229,281)(H,245,246)(H,247,248)(H,249,250)(H,251,252)(H,253,254)(H,286,287)(H4,186,187,195)(H4,188,189,196)(H4,190,191,197)(H4,192,193,198)/t91-,92-,93-,94-,95+,100-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,142-,143-,144-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 6.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [125I]-PP from human Y4R expressed in CHO-K1 cell membranes after 2 hrs by scintillation proximity assay |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 4
(Homo sapiens (Human)) | BDBM50466525
(CHEMBL4285633)Show SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCNC(N)=N)CC(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O |r| Show InChI InChI=1S/C180H278N52O55/c1-17-91(12)142(185)170(280)214-114(26-18-19-60-181)174(284)231-66-24-31-130(231)168(278)211-111(51-56-138(247)248)147(257)203-94(15)173(283)230-65-23-30-129(230)167(277)199-82-136(244)205-109(50-55-137(245)246)152(262)225-125(80-141(253)254)156(266)202-93(14)146(256)227-128(84-234)175(285)232-67-25-32-131(232)169(279)212-113(53-58-140(251)252)153(263)210-112(52-57-139(249)250)154(264)215-116(69-87(4)5)158(268)223-123(78-133(183)241)163(273)208-106(27-20-61-195-177(186)187)150(260)219-120(73-97-35-43-103(237)44-36-97)161(271)220-119(72-96-33-41-102(236)42-34-96)155(265)201-92(13)145(255)226-127(83-233)166(276)218-115(68-86(2)3)157(267)207-107(28-21-62-196-178(188)189)151(261)222-122(76-101-81-194-85-200-101)162(272)221-121(74-98-37-45-104(238)46-38-98)160(270)216-117(70-88(6)7)159(269)224-124(79-134(184)242)164(274)217-118(71-89(8)9)165(275)228-143(90(10)11)171(281)229-144(95(16)235)172(282)213-108(29-22-63-197-179(190)191)149(259)209-110(49-54-132(182)240)148(258)204-100(59-64-198-180(192)193)77-135(243)206-126(176(286)287)75-99-39-47-105(239)48-40-99/h33-48,81,85-95,100,106-131,142-144,233-239H,17-32,49-80,82-84,181,185H2,1-16H3,(H2,182,240)(H2,183,241)(H2,184,242)(H,194,200)(H,199,277)(H,201,265)(H,202,266)(H,203,257)(H,204,258)(H,205,244)(H,206,243)(H,207,267)(H,208,273)(H,209,259)(H,210,263)(H,211,278)(H,212,279)(H,213,282)(H,214,280)(H,215,264)(H,216,270)(H,217,274)(H,218,276)(H,219,260)(H,220,271)(H,221,272)(H,222,261)(H,223,268)(H,224,269)(H,225,262)(H,226,255)(H,227,256)(H,228,275)(H,229,281)(H,245,246)(H,247,248)(H,249,250)(H,251,252)(H,253,254)(H,286,287)(H4,186,187,195)(H4,188,189,196)(H4,190,191,197)(H4,192,193,198)/t91-,92-,93-,94-,95+,100-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,142-,143-,144-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 6.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [125I]-PP from human Y4R expressed in CHO-K1 cell membranes after 2 hrs by scintillation proximity assay |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 1
(Homo sapiens (Human)) | BDBM50466525
(CHEMBL4285633)Show SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCNC(N)=N)CC(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O |r| Show InChI InChI=1S/C180H278N52O55/c1-17-91(12)142(185)170(280)214-114(26-18-19-60-181)174(284)231-66-24-31-130(231)168(278)211-111(51-56-138(247)248)147(257)203-94(15)173(283)230-65-23-30-129(230)167(277)199-82-136(244)205-109(50-55-137(245)246)152(262)225-125(80-141(253)254)156(266)202-93(14)146(256)227-128(84-234)175(285)232-67-25-32-131(232)169(279)212-113(53-58-140(251)252)153(263)210-112(52-57-139(249)250)154(264)215-116(69-87(4)5)158(268)223-123(78-133(183)241)163(273)208-106(27-20-61-195-177(186)187)150(260)219-120(73-97-35-43-103(237)44-36-97)161(271)220-119(72-96-33-41-102(236)42-34-96)155(265)201-92(13)145(255)226-127(83-233)166(276)218-115(68-86(2)3)157(267)207-107(28-21-62-196-178(188)189)151(261)222-122(76-101-81-194-85-200-101)162(272)221-121(74-98-37-45-104(238)46-38-98)160(270)216-117(70-88(6)7)159(269)224-124(79-134(184)242)164(274)217-118(71-89(8)9)165(275)228-143(90(10)11)171(281)229-144(95(16)235)172(282)213-108(29-22-63-197-179(190)191)149(259)209-110(49-54-132(182)240)148(258)204-100(59-64-198-180(192)193)77-135(243)206-126(176(286)287)75-99-39-47-105(239)48-40-99/h33-48,81,85-95,100,106-131,142-144,233-239H,17-32,49-80,82-84,181,185H2,1-16H3,(H2,182,240)(H2,183,241)(H2,184,242)(H,194,200)(H,199,277)(H,201,265)(H,202,266)(H,203,257)(H,204,258)(H,205,244)(H,206,243)(H,207,267)(H,208,273)(H,209,259)(H,210,263)(H,211,278)(H,212,279)(H,213,282)(H,214,280)(H,215,264)(H,216,270)(H,217,274)(H,218,276)(H,219,260)(H,220,271)(H,221,272)(H,222,261)(H,223,268)(H,224,269)(H,225,262)(H,226,255)(H,227,256)(H,228,275)(H,229,281)(H,245,246)(H,247,248)(H,249,250)(H,251,252)(H,253,254)(H,286,287)(H4,186,187,195)(H4,188,189,196)(H4,190,191,197)(H4,192,193,198)/t91-,92-,93-,94-,95+,100-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,142-,143-,144-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [125I]-PYY(1 to 36 residues) from human Y1R expressed in BHK-21 cell membranes after 2 hrs by scintillation proximity assay |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 1
(Homo sapiens (Human)) | BDBM50466525
(CHEMBL4285633)Show SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCNC(N)=N)CC(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O |r| Show InChI InChI=1S/C180H278N52O55/c1-17-91(12)142(185)170(280)214-114(26-18-19-60-181)174(284)231-66-24-31-130(231)168(278)211-111(51-56-138(247)248)147(257)203-94(15)173(283)230-65-23-30-129(230)167(277)199-82-136(244)205-109(50-55-137(245)246)152(262)225-125(80-141(253)254)156(266)202-93(14)146(256)227-128(84-234)175(285)232-67-25-32-131(232)169(279)212-113(53-58-140(251)252)153(263)210-112(52-57-139(249)250)154(264)215-116(69-87(4)5)158(268)223-123(78-133(183)241)163(273)208-106(27-20-61-195-177(186)187)150(260)219-120(73-97-35-43-103(237)44-36-97)161(271)220-119(72-96-33-41-102(236)42-34-96)155(265)201-92(13)145(255)226-127(83-233)166(276)218-115(68-86(2)3)157(267)207-107(28-21-62-196-178(188)189)151(261)222-122(76-101-81-194-85-200-101)162(272)221-121(74-98-37-45-104(238)46-38-98)160(270)216-117(70-88(6)7)159(269)224-124(79-134(184)242)164(274)217-118(71-89(8)9)165(275)228-143(90(10)11)171(281)229-144(95(16)235)172(282)213-108(29-22-63-197-179(190)191)149(259)209-110(49-54-132(182)240)148(258)204-100(59-64-198-180(192)193)77-135(243)206-126(176(286)287)75-99-39-47-105(239)48-40-99/h33-48,81,85-95,100,106-131,142-144,233-239H,17-32,49-80,82-84,181,185H2,1-16H3,(H2,182,240)(H2,183,241)(H2,184,242)(H,194,200)(H,199,277)(H,201,265)(H,202,266)(H,203,257)(H,204,258)(H,205,244)(H,206,243)(H,207,267)(H,208,273)(H,209,259)(H,210,263)(H,211,278)(H,212,279)(H,213,282)(H,214,280)(H,215,264)(H,216,270)(H,217,274)(H,218,276)(H,219,260)(H,220,271)(H,221,272)(H,222,261)(H,223,268)(H,224,269)(H,225,262)(H,226,255)(H,227,256)(H,228,275)(H,229,281)(H,245,246)(H,247,248)(H,249,250)(H,251,252)(H,253,254)(H,286,287)(H4,186,187,195)(H4,188,189,196)(H4,190,191,197)(H4,192,193,198)/t91-,92-,93-,94-,95+,100-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,142-,143-,144-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [125I]-PYY(1 to 36 residues) from human Y1R expressed in BHK-21 cell membranes after 2 hrs by scintillation proximity assay |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 4
(Homo sapiens (Human)) | BDBM50466525
(CHEMBL4285633)Show SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCNC(N)=N)CC(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O |r| Show InChI InChI=1S/C180H278N52O55/c1-17-91(12)142(185)170(280)214-114(26-18-19-60-181)174(284)231-66-24-31-130(231)168(278)211-111(51-56-138(247)248)147(257)203-94(15)173(283)230-65-23-30-129(230)167(277)199-82-136(244)205-109(50-55-137(245)246)152(262)225-125(80-141(253)254)156(266)202-93(14)146(256)227-128(84-234)175(285)232-67-25-32-131(232)169(279)212-113(53-58-140(251)252)153(263)210-112(52-57-139(249)250)154(264)215-116(69-87(4)5)158(268)223-123(78-133(183)241)163(273)208-106(27-20-61-195-177(186)187)150(260)219-120(73-97-35-43-103(237)44-36-97)161(271)220-119(72-96-33-41-102(236)42-34-96)155(265)201-92(13)145(255)226-127(83-233)166(276)218-115(68-86(2)3)157(267)207-107(28-21-62-196-178(188)189)151(261)222-122(76-101-81-194-85-200-101)162(272)221-121(74-98-37-45-104(238)46-38-98)160(270)216-117(70-88(6)7)159(269)224-124(79-134(184)242)164(274)217-118(71-89(8)9)165(275)228-143(90(10)11)171(281)229-144(95(16)235)172(282)213-108(29-22-63-197-179(190)191)149(259)209-110(49-54-132(182)240)148(258)204-100(59-64-198-180(192)193)77-135(243)206-126(176(286)287)75-99-39-47-105(239)48-40-99/h33-48,81,85-95,100,106-131,142-144,233-239H,17-32,49-80,82-84,181,185H2,1-16H3,(H2,182,240)(H2,183,241)(H2,184,242)(H,194,200)(H,199,277)(H,201,265)(H,202,266)(H,203,257)(H,204,258)(H,205,244)(H,206,243)(H,207,267)(H,208,273)(H,209,259)(H,210,263)(H,211,278)(H,212,279)(H,213,282)(H,214,280)(H,215,264)(H,216,270)(H,217,274)(H,218,276)(H,219,260)(H,220,271)(H,221,272)(H,222,261)(H,223,268)(H,224,269)(H,225,262)(H,226,255)(H,227,256)(H,228,275)(H,229,281)(H,245,246)(H,247,248)(H,249,250)(H,251,252)(H,253,254)(H,286,287)(H4,186,187,195)(H4,188,189,196)(H4,190,191,197)(H4,192,193,198)/t91-,92-,93-,94-,95+,100-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,142-,143-,144-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Activation of human Y4R expressed in HEK293 cells assessed as inhibition of isoproterenol-induced increase in intracellular cAMP levels by calcium 5 ... |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 1
(Homo sapiens (Human)) | BDBM50466525
(CHEMBL4285633)Show SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCNC(N)=N)CC(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O |r| Show InChI InChI=1S/C180H278N52O55/c1-17-91(12)142(185)170(280)214-114(26-18-19-60-181)174(284)231-66-24-31-130(231)168(278)211-111(51-56-138(247)248)147(257)203-94(15)173(283)230-65-23-30-129(230)167(277)199-82-136(244)205-109(50-55-137(245)246)152(262)225-125(80-141(253)254)156(266)202-93(14)146(256)227-128(84-234)175(285)232-67-25-32-131(232)169(279)212-113(53-58-140(251)252)153(263)210-112(52-57-139(249)250)154(264)215-116(69-87(4)5)158(268)223-123(78-133(183)241)163(273)208-106(27-20-61-195-177(186)187)150(260)219-120(73-97-35-43-103(237)44-36-97)161(271)220-119(72-96-33-41-102(236)42-34-96)155(265)201-92(13)145(255)226-127(83-233)166(276)218-115(68-86(2)3)157(267)207-107(28-21-62-196-178(188)189)151(261)222-122(76-101-81-194-85-200-101)162(272)221-121(74-98-37-45-104(238)46-38-98)160(270)216-117(70-88(6)7)159(269)224-124(79-134(184)242)164(274)217-118(71-89(8)9)165(275)228-143(90(10)11)171(281)229-144(95(16)235)172(282)213-108(29-22-63-197-179(190)191)149(259)209-110(49-54-132(182)240)148(258)204-100(59-64-198-180(192)193)77-135(243)206-126(176(286)287)75-99-39-47-105(239)48-40-99/h33-48,81,85-95,100,106-131,142-144,233-239H,17-32,49-80,82-84,181,185H2,1-16H3,(H2,182,240)(H2,183,241)(H2,184,242)(H,194,200)(H,199,277)(H,201,265)(H,202,266)(H,203,257)(H,204,258)(H,205,244)(H,206,243)(H,207,267)(H,208,273)(H,209,259)(H,210,263)(H,211,278)(H,212,279)(H,213,282)(H,214,280)(H,215,264)(H,216,270)(H,217,274)(H,218,276)(H,219,260)(H,220,271)(H,221,272)(H,222,261)(H,223,268)(H,224,269)(H,225,262)(H,226,255)(H,227,256)(H,228,275)(H,229,281)(H,245,246)(H,247,248)(H,249,250)(H,251,252)(H,253,254)(H,286,287)(H4,186,187,195)(H4,188,189,196)(H4,190,191,197)(H4,192,193,198)/t91-,92-,93-,94-,95+,100-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,142-,143-,144-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Activation of human Y1R expressed in HEK293 cells assessed as inhibition of isoproterenol-induced increase in intracellular cAMP levels by calcium 5 ... |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50466525
(CHEMBL4285633)Show SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCNC(N)=N)CC(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O |r| Show InChI InChI=1S/C180H278N52O55/c1-17-91(12)142(185)170(280)214-114(26-18-19-60-181)174(284)231-66-24-31-130(231)168(278)211-111(51-56-138(247)248)147(257)203-94(15)173(283)230-65-23-30-129(230)167(277)199-82-136(244)205-109(50-55-137(245)246)152(262)225-125(80-141(253)254)156(266)202-93(14)146(256)227-128(84-234)175(285)232-67-25-32-131(232)169(279)212-113(53-58-140(251)252)153(263)210-112(52-57-139(249)250)154(264)215-116(69-87(4)5)158(268)223-123(78-133(183)241)163(273)208-106(27-20-61-195-177(186)187)150(260)219-120(73-97-35-43-103(237)44-36-97)161(271)220-119(72-96-33-41-102(236)42-34-96)155(265)201-92(13)145(255)226-127(83-233)166(276)218-115(68-86(2)3)157(267)207-107(28-21-62-196-178(188)189)151(261)222-122(76-101-81-194-85-200-101)162(272)221-121(74-98-37-45-104(238)46-38-98)160(270)216-117(70-88(6)7)159(269)224-124(79-134(184)242)164(274)217-118(71-89(8)9)165(275)228-143(90(10)11)171(281)229-144(95(16)235)172(282)213-108(29-22-63-197-179(190)191)149(259)209-110(49-54-132(182)240)148(258)204-100(59-64-198-180(192)193)77-135(243)206-126(176(286)287)75-99-39-47-105(239)48-40-99/h33-48,81,85-95,100,106-131,142-144,233-239H,17-32,49-80,82-84,181,185H2,1-16H3,(H2,182,240)(H2,183,241)(H2,184,242)(H,194,200)(H,199,277)(H,201,265)(H,202,266)(H,203,257)(H,204,258)(H,205,244)(H,206,243)(H,207,267)(H,208,273)(H,209,259)(H,210,263)(H,211,278)(H,212,279)(H,213,282)(H,214,280)(H,215,264)(H,216,270)(H,217,274)(H,218,276)(H,219,260)(H,220,271)(H,221,272)(H,222,261)(H,223,268)(H,224,269)(H,225,262)(H,226,255)(H,227,256)(H,228,275)(H,229,281)(H,245,246)(H,247,248)(H,249,250)(H,251,252)(H,253,254)(H,286,287)(H4,186,187,195)(H4,188,189,196)(H4,190,191,197)(H4,192,193,198)/t91-,92-,93-,94-,95+,100-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,142-,143-,144-/m0/s1 | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 50 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Activation of human Y5R expressed in HEK293 cells assessed as inhibition of isoproterenol-induced increase in intracellular cAMP levels by calcium 5 ... |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 1
(Homo sapiens (Human)) | BDBM50466525
(CHEMBL4285633)Show SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCNC(N)=N)CC(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O |r| Show InChI InChI=1S/C180H278N52O55/c1-17-91(12)142(185)170(280)214-114(26-18-19-60-181)174(284)231-66-24-31-130(231)168(278)211-111(51-56-138(247)248)147(257)203-94(15)173(283)230-65-23-30-129(230)167(277)199-82-136(244)205-109(50-55-137(245)246)152(262)225-125(80-141(253)254)156(266)202-93(14)146(256)227-128(84-234)175(285)232-67-25-32-131(232)169(279)212-113(53-58-140(251)252)153(263)210-112(52-57-139(249)250)154(264)215-116(69-87(4)5)158(268)223-123(78-133(183)241)163(273)208-106(27-20-61-195-177(186)187)150(260)219-120(73-97-35-43-103(237)44-36-97)161(271)220-119(72-96-33-41-102(236)42-34-96)155(265)201-92(13)145(255)226-127(83-233)166(276)218-115(68-86(2)3)157(267)207-107(28-21-62-196-178(188)189)151(261)222-122(76-101-81-194-85-200-101)162(272)221-121(74-98-37-45-104(238)46-38-98)160(270)216-117(70-88(6)7)159(269)224-124(79-134(184)242)164(274)217-118(71-89(8)9)165(275)228-143(90(10)11)171(281)229-144(95(16)235)172(282)213-108(29-22-63-197-179(190)191)149(259)209-110(49-54-132(182)240)148(258)204-100(59-64-198-180(192)193)77-135(243)206-126(176(286)287)75-99-39-47-105(239)48-40-99/h33-48,81,85-95,100,106-131,142-144,233-239H,17-32,49-80,82-84,181,185H2,1-16H3,(H2,182,240)(H2,183,241)(H2,184,242)(H,194,200)(H,199,277)(H,201,265)(H,202,266)(H,203,257)(H,204,258)(H,205,244)(H,206,243)(H,207,267)(H,208,273)(H,209,259)(H,210,263)(H,211,278)(H,212,279)(H,213,282)(H,214,280)(H,215,264)(H,216,270)(H,217,274)(H,218,276)(H,219,260)(H,220,271)(H,221,272)(H,222,261)(H,223,268)(H,224,269)(H,225,262)(H,226,255)(H,227,256)(H,228,275)(H,229,281)(H,245,246)(H,247,248)(H,249,250)(H,251,252)(H,253,254)(H,286,287)(H4,186,187,195)(H4,188,189,196)(H4,190,191,197)(H4,192,193,198)/t91-,92-,93-,94-,95+,100-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,142-,143-,144-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | <1.00E+3 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Activation of human Y1R expressed in HEK293 cells assessed as inhibition of isoproterenol-induced increase in intracellular cAMP levels by calcium 5 ... |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50466525
(CHEMBL4285633)Show SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCNC(N)=N)CC(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O |r| Show InChI InChI=1S/C180H278N52O55/c1-17-91(12)142(185)170(280)214-114(26-18-19-60-181)174(284)231-66-24-31-130(231)168(278)211-111(51-56-138(247)248)147(257)203-94(15)173(283)230-65-23-30-129(230)167(277)199-82-136(244)205-109(50-55-137(245)246)152(262)225-125(80-141(253)254)156(266)202-93(14)146(256)227-128(84-234)175(285)232-67-25-32-131(232)169(279)212-113(53-58-140(251)252)153(263)210-112(52-57-139(249)250)154(264)215-116(69-87(4)5)158(268)223-123(78-133(183)241)163(273)208-106(27-20-61-195-177(186)187)150(260)219-120(73-97-35-43-103(237)44-36-97)161(271)220-119(72-96-33-41-102(236)42-34-96)155(265)201-92(13)145(255)226-127(83-233)166(276)218-115(68-86(2)3)157(267)207-107(28-21-62-196-178(188)189)151(261)222-122(76-101-81-194-85-200-101)162(272)221-121(74-98-37-45-104(238)46-38-98)160(270)216-117(70-88(6)7)159(269)224-124(79-134(184)242)164(274)217-118(71-89(8)9)165(275)228-143(90(10)11)171(281)229-144(95(16)235)172(282)213-108(29-22-63-197-179(190)191)149(259)209-110(49-54-132(182)240)148(258)204-100(59-64-198-180(192)193)77-135(243)206-126(176(286)287)75-99-39-47-105(239)48-40-99/h33-48,81,85-95,100,106-131,142-144,233-239H,17-32,49-80,82-84,181,185H2,1-16H3,(H2,182,240)(H2,183,241)(H2,184,242)(H,194,200)(H,199,277)(H,201,265)(H,202,266)(H,203,257)(H,204,258)(H,205,244)(H,206,243)(H,207,267)(H,208,273)(H,209,259)(H,210,263)(H,211,278)(H,212,279)(H,213,282)(H,214,280)(H,215,264)(H,216,270)(H,217,274)(H,218,276)(H,219,260)(H,220,271)(H,221,272)(H,222,261)(H,223,268)(H,224,269)(H,225,262)(H,226,255)(H,227,256)(H,228,275)(H,229,281)(H,245,246)(H,247,248)(H,249,250)(H,251,252)(H,253,254)(H,286,287)(H4,186,187,195)(H4,188,189,196)(H4,190,191,197)(H4,192,193,198)/t91-,92-,93-,94-,95+,100-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,142-,143-,144-/m0/s1 | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 50 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Activation of human Y5R expressed in HEK293 cells assessed as inhibition of isoproterenol-induced increase in intracellular cAMP levels by calcium 5 ... |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 4
(Homo sapiens (Human)) | BDBM50466525
(CHEMBL4285633)Show SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCNC(N)=N)CC(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O |r| Show InChI InChI=1S/C180H278N52O55/c1-17-91(12)142(185)170(280)214-114(26-18-19-60-181)174(284)231-66-24-31-130(231)168(278)211-111(51-56-138(247)248)147(257)203-94(15)173(283)230-65-23-30-129(230)167(277)199-82-136(244)205-109(50-55-137(245)246)152(262)225-125(80-141(253)254)156(266)202-93(14)146(256)227-128(84-234)175(285)232-67-25-32-131(232)169(279)212-113(53-58-140(251)252)153(263)210-112(52-57-139(249)250)154(264)215-116(69-87(4)5)158(268)223-123(78-133(183)241)163(273)208-106(27-20-61-195-177(186)187)150(260)219-120(73-97-35-43-103(237)44-36-97)161(271)220-119(72-96-33-41-102(236)42-34-96)155(265)201-92(13)145(255)226-127(83-233)166(276)218-115(68-86(2)3)157(267)207-107(28-21-62-196-178(188)189)151(261)222-122(76-101-81-194-85-200-101)162(272)221-121(74-98-37-45-104(238)46-38-98)160(270)216-117(70-88(6)7)159(269)224-124(79-134(184)242)164(274)217-118(71-89(8)9)165(275)228-143(90(10)11)171(281)229-144(95(16)235)172(282)213-108(29-22-63-197-179(190)191)149(259)209-110(49-54-132(182)240)148(258)204-100(59-64-198-180(192)193)77-135(243)206-126(176(286)287)75-99-39-47-105(239)48-40-99/h33-48,81,85-95,100,106-131,142-144,233-239H,17-32,49-80,82-84,181,185H2,1-16H3,(H2,182,240)(H2,183,241)(H2,184,242)(H,194,200)(H,199,277)(H,201,265)(H,202,266)(H,203,257)(H,204,258)(H,205,244)(H,206,243)(H,207,267)(H,208,273)(H,209,259)(H,210,263)(H,211,278)(H,212,279)(H,213,282)(H,214,280)(H,215,264)(H,216,270)(H,217,274)(H,218,276)(H,219,260)(H,220,271)(H,221,272)(H,222,261)(H,223,268)(H,224,269)(H,225,262)(H,226,255)(H,227,256)(H,228,275)(H,229,281)(H,245,246)(H,247,248)(H,249,250)(H,251,252)(H,253,254)(H,286,287)(H4,186,187,195)(H4,188,189,196)(H4,190,191,197)(H4,192,193,198)/t91-,92-,93-,94-,95+,100-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,142-,143-,144-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | <1.00E+3 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Activation of human Y4R expressed in HEK293 cells assessed as inhibition of isoproterenol-induced increase in intracellular cAMP levels by calcium 5 ... |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50466525
(CHEMBL4285633)Show SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCNC(N)=N)CC(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O |r| Show InChI InChI=1S/C180H278N52O55/c1-17-91(12)142(185)170(280)214-114(26-18-19-60-181)174(284)231-66-24-31-130(231)168(278)211-111(51-56-138(247)248)147(257)203-94(15)173(283)230-65-23-30-129(230)167(277)199-82-136(244)205-109(50-55-137(245)246)152(262)225-125(80-141(253)254)156(266)202-93(14)146(256)227-128(84-234)175(285)232-67-25-32-131(232)169(279)212-113(53-58-140(251)252)153(263)210-112(52-57-139(249)250)154(264)215-116(69-87(4)5)158(268)223-123(78-133(183)241)163(273)208-106(27-20-61-195-177(186)187)150(260)219-120(73-97-35-43-103(237)44-36-97)161(271)220-119(72-96-33-41-102(236)42-34-96)155(265)201-92(13)145(255)226-127(83-233)166(276)218-115(68-86(2)3)157(267)207-107(28-21-62-196-178(188)189)151(261)222-122(76-101-81-194-85-200-101)162(272)221-121(74-98-37-45-104(238)46-38-98)160(270)216-117(70-88(6)7)159(269)224-124(79-134(184)242)164(274)217-118(71-89(8)9)165(275)228-143(90(10)11)171(281)229-144(95(16)235)172(282)213-108(29-22-63-197-179(190)191)149(259)209-110(49-54-132(182)240)148(258)204-100(59-64-198-180(192)193)77-135(243)206-126(176(286)287)75-99-39-47-105(239)48-40-99/h33-48,81,85-95,100,106-131,142-144,233-239H,17-32,49-80,82-84,181,185H2,1-16H3,(H2,182,240)(H2,183,241)(H2,184,242)(H,194,200)(H,199,277)(H,201,265)(H,202,266)(H,203,257)(H,204,258)(H,205,244)(H,206,243)(H,207,267)(H,208,273)(H,209,259)(H,210,263)(H,211,278)(H,212,279)(H,213,282)(H,214,280)(H,215,264)(H,216,270)(H,217,274)(H,218,276)(H,219,260)(H,220,271)(H,221,272)(H,222,261)(H,223,268)(H,224,269)(H,225,262)(H,226,255)(H,227,256)(H,228,275)(H,229,281)(H,245,246)(H,247,248)(H,249,250)(H,251,252)(H,253,254)(H,286,287)(H4,186,187,195)(H4,188,189,196)(H4,190,191,197)(H4,192,193,198)/t91-,92-,93-,94-,95+,100-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,142-,143-,144-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 7.90 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Activation of human Y2R expressed in HEK293 cells assessed as inhibition of isoproterenol-induced increase in intracellular cAMP levels by calcium 5 ... |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50466525
(CHEMBL4285633)Show SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCNC(N)=N)CC(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O |r| Show InChI InChI=1S/C180H278N52O55/c1-17-91(12)142(185)170(280)214-114(26-18-19-60-181)174(284)231-66-24-31-130(231)168(278)211-111(51-56-138(247)248)147(257)203-94(15)173(283)230-65-23-30-129(230)167(277)199-82-136(244)205-109(50-55-137(245)246)152(262)225-125(80-141(253)254)156(266)202-93(14)146(256)227-128(84-234)175(285)232-67-25-32-131(232)169(279)212-113(53-58-140(251)252)153(263)210-112(52-57-139(249)250)154(264)215-116(69-87(4)5)158(268)223-123(78-133(183)241)163(273)208-106(27-20-61-195-177(186)187)150(260)219-120(73-97-35-43-103(237)44-36-97)161(271)220-119(72-96-33-41-102(236)42-34-96)155(265)201-92(13)145(255)226-127(83-233)166(276)218-115(68-86(2)3)157(267)207-107(28-21-62-196-178(188)189)151(261)222-122(76-101-81-194-85-200-101)162(272)221-121(74-98-37-45-104(238)46-38-98)160(270)216-117(70-88(6)7)159(269)224-124(79-134(184)242)164(274)217-118(71-89(8)9)165(275)228-143(90(10)11)171(281)229-144(95(16)235)172(282)213-108(29-22-63-197-179(190)191)149(259)209-110(49-54-132(182)240)148(258)204-100(59-64-198-180(192)193)77-135(243)206-126(176(286)287)75-99-39-47-105(239)48-40-99/h33-48,81,85-95,100,106-131,142-144,233-239H,17-32,49-80,82-84,181,185H2,1-16H3,(H2,182,240)(H2,183,241)(H2,184,242)(H,194,200)(H,199,277)(H,201,265)(H,202,266)(H,203,257)(H,204,258)(H,205,244)(H,206,243)(H,207,267)(H,208,273)(H,209,259)(H,210,263)(H,211,278)(H,212,279)(H,213,282)(H,214,280)(H,215,264)(H,216,270)(H,217,274)(H,218,276)(H,219,260)(H,220,271)(H,221,272)(H,222,261)(H,223,268)(H,224,269)(H,225,262)(H,226,255)(H,227,256)(H,228,275)(H,229,281)(H,245,246)(H,247,248)(H,249,250)(H,251,252)(H,253,254)(H,286,287)(H4,186,187,195)(H4,188,189,196)(H4,190,191,197)(H4,192,193,198)/t91-,92-,93-,94-,95+,100-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,142-,143-,144-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 7.90 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Activation of human Y2R expressed in HEK293 cells assessed as inhibition of isoproterenol-induced increase in intracellular cAMP levels by calcium 5 ... |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |