Found 8 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Neuropeptide Y receptor type 4
(Homo sapiens (Human)) | BDBM50466560
(CHEMBL4282216)Show SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CN(C[C@H]1C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)C(N)=N |r,@@:265| Show InChI InChI=1S/C179H274N52O55/c1-17-90(12)140(184)168(278)210-111(26-18-19-59-180)172(282)229-64-24-31-128(229)165(275)206-108(51-56-136(245)246)145(255)201-93(15)171(281)228-63-23-30-127(228)164(274)197-79-134(242)202-107(50-55-135(243)244)149(259)221-123(77-139(251)252)153(263)200-92(14)144(254)224-126(82-233)174(284)230-65-25-32-129(230)166(276)207-110(53-58-138(249)250)150(260)205-109(52-57-137(247)248)151(261)211-114(67-86(4)5)155(265)219-121(75-132(182)240)160(270)204-104(27-20-60-194-176(185)186)147(257)215-118(71-96-35-43-101(236)44-36-96)158(268)216-117(70-95-33-41-100(235)42-34-95)152(262)199-91(13)143(253)223-125(81-232)163(273)214-113(66-85(2)3)154(264)203-105(28-21-61-195-177(187)188)148(258)218-120(74-99-78-193-83-198-99)159(269)217-119(72-97-37-45-102(237)46-38-97)157(267)212-115(68-87(6)7)156(266)220-122(76-133(183)241)161(271)213-116(69-88(8)9)162(272)225-141(89(10)11)169(279)226-142(94(16)234)170(280)208-106(29-22-62-196-178(189)190)146(256)209-112(49-54-131(181)239)173(283)231-84-227(179(191)192)80-130(231)167(277)222-124(175(285)286)73-98-39-47-103(238)48-40-98/h33-48,78,83,85-94,104-130,140-142,232-238H,17-32,49-77,79-82,84,180,184H2,1-16H3,(H2,181,239)(H2,182,240)(H2,183,241)(H3,191,192)(H,193,198)(H,197,274)(H,199,262)(H,200,263)(H,201,255)(H,202,242)(H,203,264)(H,204,270)(H,205,260)(H,206,275)(H,207,276)(H,208,280)(H,209,256)(H,210,278)(H,211,261)(H,212,267)(H,213,271)(H,214,273)(H,215,257)(H,216,268)(H,217,269)(H,218,258)(H,219,265)(H,220,266)(H,221,259)(H,222,277)(H,223,253)(H,224,254)(H,225,272)(H,226,279)(H,243,244)(H,245,246)(H,247,248)(H,249,250)(H,251,252)(H,285,286)(H4,185,186,194)(H4,187,188,195)(H4,189,190,196)/t90-,91-,92-,93-,94+,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,140-,141-,142-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| 6.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [125I]-PP from human Y4R expressed in CHO-K1 cell membranes after 2 hrs by scintillation proximity assay |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 4
(Homo sapiens (Human)) | BDBM50466560
(CHEMBL4282216)Show SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CN(C[C@H]1C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)C(N)=N |r,@@:265| Show InChI InChI=1S/C179H274N52O55/c1-17-90(12)140(184)168(278)210-111(26-18-19-59-180)172(282)229-64-24-31-128(229)165(275)206-108(51-56-136(245)246)145(255)201-93(15)171(281)228-63-23-30-127(228)164(274)197-79-134(242)202-107(50-55-135(243)244)149(259)221-123(77-139(251)252)153(263)200-92(14)144(254)224-126(82-233)174(284)230-65-25-32-129(230)166(276)207-110(53-58-138(249)250)150(260)205-109(52-57-137(247)248)151(261)211-114(67-86(4)5)155(265)219-121(75-132(182)240)160(270)204-104(27-20-60-194-176(185)186)147(257)215-118(71-96-35-43-101(236)44-36-96)158(268)216-117(70-95-33-41-100(235)42-34-95)152(262)199-91(13)143(253)223-125(81-232)163(273)214-113(66-85(2)3)154(264)203-105(28-21-61-195-177(187)188)148(258)218-120(74-99-78-193-83-198-99)159(269)217-119(72-97-37-45-102(237)46-38-97)157(267)212-115(68-87(6)7)156(266)220-122(76-133(183)241)161(271)213-116(69-88(8)9)162(272)225-141(89(10)11)169(279)226-142(94(16)234)170(280)208-106(29-22-62-196-178(189)190)146(256)209-112(49-54-131(181)239)173(283)231-84-227(179(191)192)80-130(231)167(277)222-124(175(285)286)73-98-39-47-103(238)48-40-98/h33-48,78,83,85-94,104-130,140-142,232-238H,17-32,49-77,79-82,84,180,184H2,1-16H3,(H2,181,239)(H2,182,240)(H2,183,241)(H3,191,192)(H,193,198)(H,197,274)(H,199,262)(H,200,263)(H,201,255)(H,202,242)(H,203,264)(H,204,270)(H,205,260)(H,206,275)(H,207,276)(H,208,280)(H,209,256)(H,210,278)(H,211,261)(H,212,267)(H,213,271)(H,214,273)(H,215,257)(H,216,268)(H,217,269)(H,218,258)(H,219,265)(H,220,266)(H,221,259)(H,222,277)(H,223,253)(H,224,254)(H,225,272)(H,226,279)(H,243,244)(H,245,246)(H,247,248)(H,249,250)(H,251,252)(H,285,286)(H4,185,186,194)(H4,187,188,195)(H4,189,190,196)/t90-,91-,92-,93-,94+,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,140-,141-,142-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 6.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [125I]-PP from human Y4R expressed in CHO-K1 cell membranes after 2 hrs by scintillation proximity assay |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50466560
(CHEMBL4282216)Show SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CN(C[C@H]1C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)C(N)=N |r,@@:265| Show InChI InChI=1S/C179H274N52O55/c1-17-90(12)140(184)168(278)210-111(26-18-19-59-180)172(282)229-64-24-31-128(229)165(275)206-108(51-56-136(245)246)145(255)201-93(15)171(281)228-63-23-30-127(228)164(274)197-79-134(242)202-107(50-55-135(243)244)149(259)221-123(77-139(251)252)153(263)200-92(14)144(254)224-126(82-233)174(284)230-65-25-32-129(230)166(276)207-110(53-58-138(249)250)150(260)205-109(52-57-137(247)248)151(261)211-114(67-86(4)5)155(265)219-121(75-132(182)240)160(270)204-104(27-20-60-194-176(185)186)147(257)215-118(71-96-35-43-101(236)44-36-96)158(268)216-117(70-95-33-41-100(235)42-34-95)152(262)199-91(13)143(253)223-125(81-232)163(273)214-113(66-85(2)3)154(264)203-105(28-21-61-195-177(187)188)148(258)218-120(74-99-78-193-83-198-99)159(269)217-119(72-97-37-45-102(237)46-38-97)157(267)212-115(68-87(6)7)156(266)220-122(76-133(183)241)161(271)213-116(69-88(8)9)162(272)225-141(89(10)11)169(279)226-142(94(16)234)170(280)208-106(29-22-62-196-178(189)190)146(256)209-112(49-54-131(181)239)173(283)231-84-227(179(191)192)80-130(231)167(277)222-124(175(285)286)73-98-39-47-103(238)48-40-98/h33-48,78,83,85-94,104-130,140-142,232-238H,17-32,49-77,79-82,84,180,184H2,1-16H3,(H2,181,239)(H2,182,240)(H2,183,241)(H3,191,192)(H,193,198)(H,197,274)(H,199,262)(H,200,263)(H,201,255)(H,202,242)(H,203,264)(H,204,270)(H,205,260)(H,206,275)(H,207,276)(H,208,280)(H,209,256)(H,210,278)(H,211,261)(H,212,267)(H,213,271)(H,214,273)(H,215,257)(H,216,268)(H,217,269)(H,218,258)(H,219,265)(H,220,266)(H,221,259)(H,222,277)(H,223,253)(H,224,254)(H,225,272)(H,226,279)(H,243,244)(H,245,246)(H,247,248)(H,249,250)(H,251,252)(H,285,286)(H4,185,186,194)(H4,187,188,195)(H4,189,190,196)/t90-,91-,92-,93-,94+,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,140-,141-,142-/m0/s1 | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 250 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [125I]-PYY(1 to 36 residues) from human Y5R expressed in HEK293 cell membranes after 2 hrs by scintillation proximity assay |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50466560
(CHEMBL4282216)Show SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CN(C[C@H]1C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)C(N)=N |r,@@:265| Show InChI InChI=1S/C179H274N52O55/c1-17-90(12)140(184)168(278)210-111(26-18-19-59-180)172(282)229-64-24-31-128(229)165(275)206-108(51-56-136(245)246)145(255)201-93(15)171(281)228-63-23-30-127(228)164(274)197-79-134(242)202-107(50-55-135(243)244)149(259)221-123(77-139(251)252)153(263)200-92(14)144(254)224-126(82-233)174(284)230-65-25-32-129(230)166(276)207-110(53-58-138(249)250)150(260)205-109(52-57-137(247)248)151(261)211-114(67-86(4)5)155(265)219-121(75-132(182)240)160(270)204-104(27-20-60-194-176(185)186)147(257)215-118(71-96-35-43-101(236)44-36-96)158(268)216-117(70-95-33-41-100(235)42-34-95)152(262)199-91(13)143(253)223-125(81-232)163(273)214-113(66-85(2)3)154(264)203-105(28-21-61-195-177(187)188)148(258)218-120(74-99-78-193-83-198-99)159(269)217-119(72-97-37-45-102(237)46-38-97)157(267)212-115(68-87(6)7)156(266)220-122(76-133(183)241)161(271)213-116(69-88(8)9)162(272)225-141(89(10)11)169(279)226-142(94(16)234)170(280)208-106(29-22-62-196-178(189)190)146(256)209-112(49-54-131(181)239)173(283)231-84-227(179(191)192)80-130(231)167(277)222-124(175(285)286)73-98-39-47-103(238)48-40-98/h33-48,78,83,85-94,104-130,140-142,232-238H,17-32,49-77,79-82,84,180,184H2,1-16H3,(H2,181,239)(H2,182,240)(H2,183,241)(H3,191,192)(H,193,198)(H,197,274)(H,199,262)(H,200,263)(H,201,255)(H,202,242)(H,203,264)(H,204,270)(H,205,260)(H,206,275)(H,207,276)(H,208,280)(H,209,256)(H,210,278)(H,211,261)(H,212,267)(H,213,271)(H,214,273)(H,215,257)(H,216,268)(H,217,269)(H,218,258)(H,219,265)(H,220,266)(H,221,259)(H,222,277)(H,223,253)(H,224,254)(H,225,272)(H,226,279)(H,243,244)(H,245,246)(H,247,248)(H,249,250)(H,251,252)(H,285,286)(H4,185,186,194)(H4,187,188,195)(H4,189,190,196)/t90-,91-,92-,93-,94+,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,140-,141-,142-/m0/s1 | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 251 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [125I]-PYY(1 to 36 residues) from human Y5R expressed in HEK293 cell membranes after 2 hrs by scintillation proximity assay |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 1
(Homo sapiens (Human)) | BDBM50466560
(CHEMBL4282216)Show SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CN(C[C@H]1C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)C(N)=N |r,@@:265| Show InChI InChI=1S/C179H274N52O55/c1-17-90(12)140(184)168(278)210-111(26-18-19-59-180)172(282)229-64-24-31-128(229)165(275)206-108(51-56-136(245)246)145(255)201-93(15)171(281)228-63-23-30-127(228)164(274)197-79-134(242)202-107(50-55-135(243)244)149(259)221-123(77-139(251)252)153(263)200-92(14)144(254)224-126(82-233)174(284)230-65-25-32-129(230)166(276)207-110(53-58-138(249)250)150(260)205-109(52-57-137(247)248)151(261)211-114(67-86(4)5)155(265)219-121(75-132(182)240)160(270)204-104(27-20-60-194-176(185)186)147(257)215-118(71-96-35-43-101(236)44-36-96)158(268)216-117(70-95-33-41-100(235)42-34-95)152(262)199-91(13)143(253)223-125(81-232)163(273)214-113(66-85(2)3)154(264)203-105(28-21-61-195-177(187)188)148(258)218-120(74-99-78-193-83-198-99)159(269)217-119(72-97-37-45-102(237)46-38-97)157(267)212-115(68-87(6)7)156(266)220-122(76-133(183)241)161(271)213-116(69-88(8)9)162(272)225-141(89(10)11)169(279)226-142(94(16)234)170(280)208-106(29-22-62-196-178(189)190)146(256)209-112(49-54-131(181)239)173(283)231-84-227(179(191)192)80-130(231)167(277)222-124(175(285)286)73-98-39-47-103(238)48-40-98/h33-48,78,83,85-94,104-130,140-142,232-238H,17-32,49-77,79-82,84,180,184H2,1-16H3,(H2,181,239)(H2,182,240)(H2,183,241)(H3,191,192)(H,193,198)(H,197,274)(H,199,262)(H,200,263)(H,201,255)(H,202,242)(H,203,264)(H,204,270)(H,205,260)(H,206,275)(H,207,276)(H,208,280)(H,209,256)(H,210,278)(H,211,261)(H,212,267)(H,213,271)(H,214,273)(H,215,257)(H,216,268)(H,217,269)(H,218,258)(H,219,265)(H,220,266)(H,221,259)(H,222,277)(H,223,253)(H,224,254)(H,225,272)(H,226,279)(H,243,244)(H,245,246)(H,247,248)(H,249,250)(H,251,252)(H,285,286)(H4,185,186,194)(H4,187,188,195)(H4,189,190,196)/t90-,91-,92-,93-,94+,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,140-,141-,142-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [125I]-PYY(1 to 36 residues) from human Y1R expressed in BHK-21 cell membranes after 2 hrs by scintillation proximity assay |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 1
(Homo sapiens (Human)) | BDBM50466560
(CHEMBL4282216)Show SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CN(C[C@H]1C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)C(N)=N |r,@@:265| Show InChI InChI=1S/C179H274N52O55/c1-17-90(12)140(184)168(278)210-111(26-18-19-59-180)172(282)229-64-24-31-128(229)165(275)206-108(51-56-136(245)246)145(255)201-93(15)171(281)228-63-23-30-127(228)164(274)197-79-134(242)202-107(50-55-135(243)244)149(259)221-123(77-139(251)252)153(263)200-92(14)144(254)224-126(82-233)174(284)230-65-25-32-129(230)166(276)207-110(53-58-138(249)250)150(260)205-109(52-57-137(247)248)151(261)211-114(67-86(4)5)155(265)219-121(75-132(182)240)160(270)204-104(27-20-60-194-176(185)186)147(257)215-118(71-96-35-43-101(236)44-36-96)158(268)216-117(70-95-33-41-100(235)42-34-95)152(262)199-91(13)143(253)223-125(81-232)163(273)214-113(66-85(2)3)154(264)203-105(28-21-61-195-177(187)188)148(258)218-120(74-99-78-193-83-198-99)159(269)217-119(72-97-37-45-102(237)46-38-97)157(267)212-115(68-87(6)7)156(266)220-122(76-133(183)241)161(271)213-116(69-88(8)9)162(272)225-141(89(10)11)169(279)226-142(94(16)234)170(280)208-106(29-22-62-196-178(189)190)146(256)209-112(49-54-131(181)239)173(283)231-84-227(179(191)192)80-130(231)167(277)222-124(175(285)286)73-98-39-47-103(238)48-40-98/h33-48,78,83,85-94,104-130,140-142,232-238H,17-32,49-77,79-82,84,180,184H2,1-16H3,(H2,181,239)(H2,182,240)(H2,183,241)(H3,191,192)(H,193,198)(H,197,274)(H,199,262)(H,200,263)(H,201,255)(H,202,242)(H,203,264)(H,204,270)(H,205,260)(H,206,275)(H,207,276)(H,208,280)(H,209,256)(H,210,278)(H,211,261)(H,212,267)(H,213,271)(H,214,273)(H,215,257)(H,216,268)(H,217,269)(H,218,258)(H,219,265)(H,220,266)(H,221,259)(H,222,277)(H,223,253)(H,224,254)(H,225,272)(H,226,279)(H,243,244)(H,245,246)(H,247,248)(H,249,250)(H,251,252)(H,285,286)(H4,185,186,194)(H4,187,188,195)(H4,189,190,196)/t90-,91-,92-,93-,94+,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,140-,141-,142-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [125I]-PYY(1 to 36 residues) from human Y1R expressed in BHK-21 cell membranes after 2 hrs by scintillation proximity assay |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50466560
(CHEMBL4282216)Show SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CN(C[C@H]1C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)C(N)=N |r,@@:265| Show InChI InChI=1S/C179H274N52O55/c1-17-90(12)140(184)168(278)210-111(26-18-19-59-180)172(282)229-64-24-31-128(229)165(275)206-108(51-56-136(245)246)145(255)201-93(15)171(281)228-63-23-30-127(228)164(274)197-79-134(242)202-107(50-55-135(243)244)149(259)221-123(77-139(251)252)153(263)200-92(14)144(254)224-126(82-233)174(284)230-65-25-32-129(230)166(276)207-110(53-58-138(249)250)150(260)205-109(52-57-137(247)248)151(261)211-114(67-86(4)5)155(265)219-121(75-132(182)240)160(270)204-104(27-20-60-194-176(185)186)147(257)215-118(71-96-35-43-101(236)44-36-96)158(268)216-117(70-95-33-41-100(235)42-34-95)152(262)199-91(13)143(253)223-125(81-232)163(273)214-113(66-85(2)3)154(264)203-105(28-21-61-195-177(187)188)148(258)218-120(74-99-78-193-83-198-99)159(269)217-119(72-97-37-45-102(237)46-38-97)157(267)212-115(68-87(6)7)156(266)220-122(76-133(183)241)161(271)213-116(69-88(8)9)162(272)225-141(89(10)11)169(279)226-142(94(16)234)170(280)208-106(29-22-62-196-178(189)190)146(256)209-112(49-54-131(181)239)173(283)231-84-227(179(191)192)80-130(231)167(277)222-124(175(285)286)73-98-39-47-103(238)48-40-98/h33-48,78,83,85-94,104-130,140-142,232-238H,17-32,49-77,79-82,84,180,184H2,1-16H3,(H2,181,239)(H2,182,240)(H2,183,241)(H3,191,192)(H,193,198)(H,197,274)(H,199,262)(H,200,263)(H,201,255)(H,202,242)(H,203,264)(H,204,270)(H,205,260)(H,206,275)(H,207,276)(H,208,280)(H,209,256)(H,210,278)(H,211,261)(H,212,267)(H,213,271)(H,214,273)(H,215,257)(H,216,268)(H,217,269)(H,218,258)(H,219,265)(H,220,266)(H,221,259)(H,222,277)(H,223,253)(H,224,254)(H,225,272)(H,226,279)(H,243,244)(H,245,246)(H,247,248)(H,249,250)(H,251,252)(H,285,286)(H4,185,186,194)(H4,187,188,195)(H4,189,190,196)/t90-,91-,92-,93-,94+,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,140-,141-,142-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 7.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [125I]-PYY(1 to 36 residues) from human Y2R expressed in CHO cell membranes after 2 hrs by scintillation proximity assay |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50466560
(CHEMBL4282216)Show SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CN(C[C@H]1C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)C(N)=N |r,@@:265| Show InChI InChI=1S/C179H274N52O55/c1-17-90(12)140(184)168(278)210-111(26-18-19-59-180)172(282)229-64-24-31-128(229)165(275)206-108(51-56-136(245)246)145(255)201-93(15)171(281)228-63-23-30-127(228)164(274)197-79-134(242)202-107(50-55-135(243)244)149(259)221-123(77-139(251)252)153(263)200-92(14)144(254)224-126(82-233)174(284)230-65-25-32-129(230)166(276)207-110(53-58-138(249)250)150(260)205-109(52-57-137(247)248)151(261)211-114(67-86(4)5)155(265)219-121(75-132(182)240)160(270)204-104(27-20-60-194-176(185)186)147(257)215-118(71-96-35-43-101(236)44-36-96)158(268)216-117(70-95-33-41-100(235)42-34-95)152(262)199-91(13)143(253)223-125(81-232)163(273)214-113(66-85(2)3)154(264)203-105(28-21-61-195-177(187)188)148(258)218-120(74-99-78-193-83-198-99)159(269)217-119(72-97-37-45-102(237)46-38-97)157(267)212-115(68-87(6)7)156(266)220-122(76-133(183)241)161(271)213-116(69-88(8)9)162(272)225-141(89(10)11)169(279)226-142(94(16)234)170(280)208-106(29-22-62-196-178(189)190)146(256)209-112(49-54-131(181)239)173(283)231-84-227(179(191)192)80-130(231)167(277)222-124(175(285)286)73-98-39-47-103(238)48-40-98/h33-48,78,83,85-94,104-130,140-142,232-238H,17-32,49-77,79-82,84,180,184H2,1-16H3,(H2,181,239)(H2,182,240)(H2,183,241)(H3,191,192)(H,193,198)(H,197,274)(H,199,262)(H,200,263)(H,201,255)(H,202,242)(H,203,264)(H,204,270)(H,205,260)(H,206,275)(H,207,276)(H,208,280)(H,209,256)(H,210,278)(H,211,261)(H,212,267)(H,213,271)(H,214,273)(H,215,257)(H,216,268)(H,217,269)(H,218,258)(H,219,265)(H,220,266)(H,221,259)(H,222,277)(H,223,253)(H,224,254)(H,225,272)(H,226,279)(H,243,244)(H,245,246)(H,247,248)(H,249,250)(H,251,252)(H,285,286)(H4,185,186,194)(H4,187,188,195)(H4,189,190,196)/t90-,91-,92-,93-,94+,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,140-,141-,142-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 7.94E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [125I]-PYY(1 to 36 residues) from human Y2R expressed in CHO cell membranes after 2 hrs by scintillation proximity assay |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |