Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Alkaline phosphatase, tissue-nonspecific isozyme
(Homo sapiens (Human)) | BDBM275083
(US10221195, Example 25 | US9879032, Example 25)Show SMILES CC[C@H]1COc2ncc(NS(=O)(=O)c3cc(Cl)ccc3OC)cc2C(=O)N1 |r| Show InChI InChI=1S/C17H18ClN3O5S/c1-3-11-9-26-17-13(16(22)20-11)7-12(8-19-17)21-27(23,24)15-6-10(18)4-5-14(15)25-2/h4-8,11,21H,3,9H2,1-2H3,(H,20,22)/t11-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Company, Limited; Sanford Burnham Prebys Medical Discovery Institute
US Patent
| Assay Description
COS1 cells (DS Pharma Biomedical Co., Ltd.) were transfected with human TNAP (OriGene Technologies, Inc.) using Lipofectamine LTX & Plus reagent (Inv... |
US Patent US10221195 (2019)
BindingDB Entry DOI: 10.7270/Q2QZ2D83 |
More data for this
Ligand-Target Pair | |
Alkaline phosphatase, tissue-nonspecific isozyme
(Homo sapiens (Human)) | BDBM275083
(US10221195, Example 25 | US9879032, Example 25)Show SMILES CC[C@H]1COc2ncc(NS(=O)(=O)c3cc(Cl)ccc3OC)cc2C(=O)N1 |r| Show InChI InChI=1S/C17H18ClN3O5S/c1-3-11-9-26-17-13(16(22)20-11)7-12(8-19-17)21-27(23,24)15-6-10(18)4-5-14(15)25-2/h4-8,11,21H,3,9H2,1-2H3,(H,20,22)/t11-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | 25 |
Daiichi Sankyo Company, Limited; Sandford Burnham Prebys Medical Discovery Institute
US Patent
| Assay Description
COS 1 cells (DS Pharma Biomedical Co., Ltd.) were transfected with human TNAP (OriGene Technologies, Inc.) using Lipofectamine LTX & Plus reagent (In... |
US Patent US9879032 (2018)
BindingDB Entry DOI: 10.7270/Q2F76FKB |
More data for this
Ligand-Target Pair | |