Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
C-X-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50413567
(CHEMBL511976)Show SMILES CC1(C)[C@@H]2CC[C@@]1(C)[C@@H](C2)NC1CCN(Cc2c(F)c(F)c(F)c(F)c2F)CC1 |r,THB:10:8:5.4:1| Show InChI InChI=1S/C22H29F5N2/c1-21(2)12-4-7-22(21,3)15(10-12)28-13-5-8-29(9-6-13)11-14-16(23)18(25)20(27)19(26)17(14)24/h12-13,15,28H,4-11H2,1-3H3/t12-,15-,22+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 501 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
VU University Amsterdam
Curated by ChEMBL
| Assay Description
Displacement of [125I]CXCL10 from human CXCR3 expressed in HEK293T cells |
Bioorg Med Chem Lett 19: 2252-7 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.093
BindingDB Entry DOI: 10.7270/Q2DJ5GW6 |
More data for this
Ligand-Target Pair | |
C-X-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50413567
(CHEMBL511976)Show SMILES CC1(C)[C@@H]2CC[C@@]1(C)[C@@H](C2)NC1CCN(Cc2c(F)c(F)c(F)c(F)c2F)CC1 |r,THB:10:8:5.4:1| Show InChI InChI=1S/C22H29F5N2/c1-21(2)12-4-7-22(21,3)15(10-12)28-13-5-8-29(9-6-13)11-14-16(23)18(25)20(27)19(26)17(14)24/h12-13,15,28H,4-11H2,1-3H3/t12-,15-,22+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 501 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
VU University Amsterdam
Curated by ChEMBL
| Assay Description
Antagonist activity at human CXCR3 expressed in HEK293T cells coexpressing Galphaqi5 assessed as inhibition of CXCL10-induced [3H]inositol phosphate ... |
Bioorg Med Chem Lett 19: 2252-7 (2009)
Article DOI: 10.1016/j.bmcl.2009.02.093
BindingDB Entry DOI: 10.7270/Q2DJ5GW6 |
More data for this
Ligand-Target Pair | |