Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 265.2 BDBM50291679

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 2 (Rattus norvegicus)	BDBM50291679 (4-Amino-2,2-dimethyl-chroman-4,7-dicarboxylic acid...) Show SMILES CC1(C)CC(N)(C(O)=O)c2ccc(cc2O1)C(O)=O Show InChI InChI=1S/C13H15NO5/c1-12(2)6-13(14,11(17)18)8-4-3-7(10(15)16)5-9(8)19-12/h3-5H,6,14H2,1-2H3,(H,15,16)(H,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	4.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonistic activity of the compound against Metabotropic glutamate receptor 2 was determined				Bioorg Med Chem Lett 7: 1195-1198 (1997) Article DOI: 10.1016/S0960-894X(97)00177-7 BindingDB Entry DOI: 10.7270/Q2MC901V
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50291679 (4-Amino-2,2-dimethyl-chroman-4,7-dicarboxylic acid...) Show SMILES CC1(C)CC(N)(C(O)=O)c2ccc(cc2O1)C(O)=O Show InChI InChI=1S/C13H15NO5/c1-12(2)6-13(14,11(17)18)8-4-3-7(10(15)16)5-9(8)19-12/h3-5H,6,14H2,1-2H3,(H,15,16)(H,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	9.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonistic activity of the compound against Metabotropic glutamate receptor 1 was determined				Bioorg Med Chem Lett 7: 1195-1198 (1997) Article DOI: 10.1016/S0960-894X(97)00177-7 BindingDB Entry DOI: 10.7270/Q2MC901V
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50291679 (4-Amino-2,2-dimethyl-chroman-4,7-dicarboxylic acid...) Show SMILES CC1(C)CC(N)(C(O)=O)c2ccc(cc2O1)C(O)=O Show InChI InChI=1S/C13H15NO5/c1-12(2)6-13(14,11(17)18)8-4-3-7(10(15)16)5-9(8)19-12/h3-5H,6,14H2,1-2H3,(H,15,16)(H,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	3.55E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonistic activity of the compound against Metabotropic glutamate receptor 5 was determined				Bioorg Med Chem Lett 7: 1195-1198 (1997) Article DOI: 10.1016/S0960-894X(97)00177-7 BindingDB Entry DOI: 10.7270/Q2MC901V
					More data for this Ligand-Target Pair