Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 420.4 BDBM50506960

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM50506960 (CHEMBL4528846) Show SMILES CC1(C)CN(CCN1)c1ccc2nc(c(-c3ccncc3)n2n1)-c1cc(F)cc(F)c1 Show InChI InChI=1S/C23H22F2N6/c1-23(2)14-30(10-9-27-23)20-4-3-19-28-21(16-11-17(24)13-18(25)12-16)22(31(19)29-20)15-5-7-26-8-6-15/h3-8,11-13,27H,9-10,14H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Curated by ChEMBL					Assay Description Inhibition of human CK1 epsilon using casein as substrate after 2 hrs in presence of [33P]-ATP by scintillation counting analysis				Bioorg Med Chem Lett 28: 3681-3684 (2018) Article DOI: 10.1016/j.bmcl.2018.10.031 BindingDB Entry DOI: 10.7270/Q2MP56JN
					More data for this Ligand-Target Pair