Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Cytochrome P450 11B1, mitochondrial
(Homo sapiens (Human)) | BDBM101388
(US9695152, 9)Show SMILES CC1(C)N(C(=O)c2ccc(Cl)cc12)c1cncc(NC2CN(C2)C(=O)c2ncccc2Cl)c1 Show InChI InChI=1S/C24H21Cl2N5O2/c1-24(2)19-8-14(25)5-6-18(19)22(32)31(24)17-9-15(10-27-11-17)29-16-12-30(13-16)23(33)21-20(26)4-3-7-28-21/h3-11,16,29H,12-13H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| US Patent
| n/a | n/a | n/a | n/a | 297 | n/a | n/a | n/a | 37 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-2007 co... |
US Patent US9695152 (2017)
BindingDB Entry DOI: 10.7270/Q2FN14BQ |
More data for this Ligand-Target Pair | |
Cytochrome P450 11B2, mitochondrial
(Homo sapiens (Human)) | BDBM101388
(US9695152, 9)Show SMILES CC1(C)N(C(=O)c2ccc(Cl)cc12)c1cncc(NC2CN(C2)C(=O)c2ncccc2Cl)c1 Show InChI InChI=1S/C24H21Cl2N5O2/c1-24(2)19-8-14(25)5-6-18(19)22(32)31(24)17-9-15(10-27-11-17)29-16-12-30(13-16)23(33)21-20(26)4-3-7-28-21/h3-11,16,29H,12-13H2,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| US Patent
| n/a | n/a | n/a | n/a | 7 | n/a | n/a | n/a | 37 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-2007 co... |
US Patent US9695152 (2017)
BindingDB Entry DOI: 10.7270/Q2FN14BQ |
More data for this Ligand-Target Pair | |