Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cytochrome P450 11B1, mitochondrial
(Homo sapiens (Human)) | BDBM101341
(US9695151, 8)Show SMILES CC1(C)N(C(=O)c2ccc(Cl)cc12)c1cncc(NC2CN(C2)S(C)(=O)=O)c1 Show InChI InChI=1S/C19H21ClN4O3S/c1-19(2)17-6-12(20)4-5-16(17)18(25)24(19)15-7-13(8-21-9-15)22-14-10-23(11-14)28(3,26)27/h4-9,14,22H,10-11H2,1-3H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | n/a | n/a | 2.80E+3 | n/a | n/a | n/a | 37 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-2007 co... |
US Patent US9695151 (2017)
BindingDB Entry DOI: 10.7270/Q2KD1W22 |
More data for this
Ligand-Target Pair | |
Cytochrome P450 11B2, mitochondrial
(Homo sapiens (Human)) | BDBM101341
(US9695151, 8)Show SMILES CC1(C)N(C(=O)c2ccc(Cl)cc12)c1cncc(NC2CN(C2)S(C)(=O)=O)c1 Show InChI InChI=1S/C19H21ClN4O3S/c1-19(2)17-6-12(20)4-5-16(17)18(25)24(19)15-7-13(8-21-9-15)22-14-10-23(11-14)28(3,26)27/h4-9,14,22H,10-11H2,1-3H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | n/a | n/a | 17 | n/a | n/a | n/a | 37 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description
G-402 cells expressing CYP11 constructs were established as described above and maintained in McCoy's 5a Medium Modified, ATCC Catalog No. 30-2007 co... |
US Patent US9695151 (2017)
BindingDB Entry DOI: 10.7270/Q2KD1W22 |
More data for this
Ligand-Target Pair | |