Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Beta-lactamase TEM
(Escherichia coli) | BDBM50076675
(CHEMBL265722 | Sodium; (2S,5R,6R)-6-hydroxymethyl-...)Show SMILES CC1(C)S[C@@H]2[C@H](CO)C(=O)N2[C@H]1C([O-])=O Show InChI InChI=1S/C9H13NO4S/c1-9(2)5(8(13)14)10-6(12)4(3-11)7(10)15-9/h4-5,7,11H,3H2,1-2H3,(H,13,14)/p-1/t4-,5+,7-/m1/s1 | PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 3.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research
Curated by ChEMBL
| Assay Description Inhibitory activity of the compound against TEM-1 (class A) beta-lactamase |
Bioorg Med Chem Lett 9: 991-6 (1999)
BindingDB Entry DOI: 10.7270/Q2TB163Q |
More data for this Ligand-Target Pair | |
Beta-lactamase
(Escherichia coli) | BDBM50076675
(CHEMBL265722 | Sodium; (2S,5R,6R)-6-hydroxymethyl-...)Show SMILES CC1(C)S[C@@H]2[C@H](CO)C(=O)N2[C@H]1C([O-])=O Show InChI InChI=1S/C9H13NO4S/c1-9(2)5(8(13)14)10-6(12)4(3-11)7(10)15-9/h4-5,7,11H,3H2,1-2H3,(H,13,14)/p-1/t4-,5+,7-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 6.59E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research
Curated by ChEMBL
| Assay Description Inhibitory activity of the compound against AmpC (class C) beta-lactamase |
Bioorg Med Chem Lett 9: 991-6 (1999)
BindingDB Entry DOI: 10.7270/Q2TB163Q |
More data for this Ligand-Target Pair | |