Found 4 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Metallo-beta-lactamase L1 type 3
(Stenotrophomonas maltophilia) | BDBM50140665
((2S,5R,6R)-6-Mercapto-3,3-dimethyl-7-oxo-4-thia-1-...)Show InChI InChI=1S/C8H11NO3S2/c1-8(2)4(7(11)12)9-5(10)3(13)6(9)14-8/h3-4,6,13H,1-2H3,(H,11,12)/t3-,4+,6-/m1/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.14E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Methodist University
Curated by ChEMBL
| Assay Description Beta-Lactamase Inhibition of metallo-beta-lactamase representative class B (L1) enzyme |
Bioorg Med Chem Lett 14: 1299-304 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.037 BindingDB Entry DOI: 10.7270/Q22Z14ZG |
More data for this Ligand-Target Pair | |
Metallo-beta-lactamase type 2
(Bacillus cereus) | BDBM50140665
((2S,5R,6R)-6-Mercapto-3,3-dimethyl-7-oxo-4-thia-1-...)Show InChI InChI=1S/C8H11NO3S2/c1-8(2)4(7(11)12)9-5(10)3(13)6(9)14-8/h3-4,6,13H,1-2H3,(H,11,12)/t3-,4+,6-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.14E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Methodist University
Curated by ChEMBL
| Assay Description Beta-Lactamase Inhibition of metallo-beta-lactamase representative class B (L1) enzyme |
Bioorg Med Chem Lett 14: 1299-304 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.037 BindingDB Entry DOI: 10.7270/Q22Z14ZG |
More data for this Ligand-Target Pair | |
Beta-lactamase
(Escherichia coli) | BDBM50140665
((2S,5R,6R)-6-Mercapto-3,3-dimethyl-7-oxo-4-thia-1-...)Show InChI InChI=1S/C8H11NO3S2/c1-8(2)4(7(11)12)9-5(10)3(13)6(9)14-8/h3-4,6,13H,1-2H3,(H,11,12)/t3-,4+,6-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.23E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Methodist University
Curated by ChEMBL
| Assay Description Beta-Lactamase inhibitory activity against representativeclass C (P99) serine enzyme |
Bioorg Med Chem Lett 14: 1299-304 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.037 BindingDB Entry DOI: 10.7270/Q22Z14ZG |
More data for this Ligand-Target Pair | |
Beta-lactamase TEM
(Escherichia coli) | BDBM50140665
((2S,5R,6R)-6-Mercapto-3,3-dimethyl-7-oxo-4-thia-1-...)Show InChI InChI=1S/C8H11NO3S2/c1-8(2)4(7(11)12)9-5(10)3(13)6(9)14-8/h3-4,6,13H,1-2H3,(H,11,12)/t3-,4+,6-/m1/s1 | PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Methodist University
Curated by ChEMBL
| Assay Description Beta-Lactamase inhibitory activity against representative class A (TEM-1) serine enzyme |
Bioorg Med Chem Lett 14: 1299-304 (2004)
Article DOI: 10.1016/j.bmcl.2003.12.037 BindingDB Entry DOI: 10.7270/Q22Z14ZG |
More data for this Ligand-Target Pair | |