Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 380.4 BDBM372497

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372497 (N-[2-(4-Fluoro-benzyl)-2H-[1,2,3]triazol-4-yl]-2-[...) Show SMILES CC1(COC1)c1ccc(CC(=O)Nc2cnn(Cc3ccc(F)cc3)n2)cc1 Show InChI InChI=1S/C21H21FN4O2/c1-21(13-28-14-21)17-6-2-15(3-7-17)10-20(27)24-19-11-23-26(25-19)12-16-4-8-18(22)9-5-16/h2-9,11H,10,12-14H2,1H3,(H,24,25,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair