Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 515.5 BDBM627259

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM627259 (1-(3-cyano-3-methylcyclobutyl)- 3-(3-(difluorometh...) Show SMILES CC1(CS(=O)(=O)C1)NC(=O)c1cnc2c(nn([C@H]3C[C@@](C)(C3)C#N)c2c1)-c1cccc(OC(F)F)c1 |r,wU:19.23,wD:17.17,19.20,(6.95,-1.67,;6.18,-3,;7.52,-3.77,;6.75,-5.11,;7.86,-6.17,;6.31,-6.58,;5.41,-4.34,;4.85,-2.23,;4.85,-.69,;6.18,.08,;3.52,.08,;3.52,1.62,;2.18,2.39,;.85,1.62,;-.62,2.09,;-1.52,.85,;-.62,-.4,;-1.09,-1.86,;-2.46,-2.56,;-1.76,-3.94,;-1.41,-5.43,;-.39,-3.24,;-2.94,-4.94,;-4.11,-5.94,;.85,.08,;2.18,-.69,;-1.09,3.56,;-.06,4.7,;-.54,6.17,;-2.04,6.49,;-3.07,5.34,;-4.58,5.66,;-5.06,7.13,;-6.56,7.45,;-4.03,8.27,;-2.6,3.88,)| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
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