Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Programmed cell death 1 ligand 1
(Homo sapiens (Human)) | BDBM482582
(US10919852, Compound TABLE 1.281 | US11708326, Com...)Show SMILES CC1(F)CCN(CCCOc2cccc(c2Cl)-c2cccc3[C@H](CCc23)Oc2cc(OCc3cncc(c3)C#N)c(CNC[C@H]3CCC(=O)N3)cc2Cl)CC1 |r| Show InChI InChI=1S/C43H46Cl2FN5O4/c1-43(46)13-16-51(17-14-43)15-4-18-53-38-8-3-7-35(42(38)45)32-5-2-6-34-33(32)10-11-37(34)55-40-21-39(54-27-29-19-28(22-47)23-48-24-29)30(20-36(40)44)25-49-26-31-9-12-41(52)50-31/h2-3,5-8,19-21,23-24,31,37,49H,4,9-18,25-27H2,1H3,(H,50,52)/t31-,37+/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| | n/a | n/a | 253 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q22N56DJ |
More data for this
Ligand-Target Pair | |
Programmed cell death protein 1
(Homo sapiens) | BDBM482582
(US10919852, Compound TABLE 1.281 | US11708326, Com...)Show SMILES CC1(F)CCN(CCCOc2cccc(c2Cl)-c2cccc3[C@H](CCc23)Oc2cc(OCc3cncc(c3)C#N)c(CNC[C@H]3CCC(=O)N3)cc2Cl)CC1 |r| Show InChI InChI=1S/C43H46Cl2FN5O4/c1-43(46)13-16-51(17-14-43)15-4-18-53-38-8-3-7-35(42(38)45)32-5-2-6-34-33(32)10-11-37(34)55-40-21-39(54-27-29-19-28(22-47)23-48-24-29)30(20-36(40)44)25-49-26-31-9-12-41(52)50-31/h2-3,5-8,19-21,23-24,31,37,49H,4,9-18,25-27H2,1H3,(H,50,52)/t31-,37+/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 253 | n/a | n/a | n/a | n/a | n/a | n/a |
ChemoCentryx, Inc.
US Patent
| Assay Description
96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W... |
US Patent US10919852 (2021)
BindingDB Entry DOI: 10.7270/Q2RF5Z3R |
More data for this
Ligand-Target Pair | |