Found 3 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50072010
(2,2,4-trimethyl-8-nitro-2,10-dihydro-1H-indeno[1,2...)Show SMILES CC1=CC(C)(C)Nc2cc3Cc4cc(ccc4-c3cc12)[N+]([O-])=O |t:1| Show InChI InChI=1S/C19H18N2O2/c1-11-10-19(2,3)20-18-8-13-6-12-7-14(21(22)23)4-5-15(12)17(13)9-16(11)18/h4-5,7-10,20H,6H2,1-3H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 3.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description Binding affinity against human progesterone receptor-A (hPR-A) |
Bioorg Med Chem Lett 8: 2731-6 (1999)
BindingDB Entry DOI: 10.7270/Q2QF8S1M |
More data for this Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50072010
(2,2,4-trimethyl-8-nitro-2,10-dihydro-1H-indeno[1,2...)Show SMILES CC1=CC(C)(C)Nc2cc3Cc4cc(ccc4-c3cc12)[N+]([O-])=O |t:1| Show InChI InChI=1S/C19H18N2O2/c1-11-10-19(2,3)20-18-8-13-6-12-7-14(21(22)23)4-5-15(12)17(13)9-16(11)18/h4-5,7-10,20H,6H2,1-3H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Scientific Computing Ltd.
Curated by ChEMBL
| Assay Description Displacement of [3H]progesterone from Progesterone receptor |
J Med Chem 49: 4261-8 (2006)
Article DOI: 10.1021/jm060234e BindingDB Entry DOI: 10.7270/Q2V69NB6 |
More data for this Ligand-Target Pair | |
Progesterone receptor
(Homo sapiens (Human)) | BDBM50072010
(2,2,4-trimethyl-8-nitro-2,10-dihydro-1H-indeno[1,2...)Show SMILES CC1=CC(C)(C)Nc2cc3Cc4cc(ccc4-c3cc12)[N+]([O-])=O |t:1| Show InChI InChI=1S/C19H18N2O2/c1-11-10-19(2,3)20-18-8-13-6-12-7-14(21(22)23)4-5-15(12)17(13)9-16(11)18/h4-5,7-10,20H,6H2,1-3H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description Antagonist activity against human progesterone receptor B (hPR-B) in cotransfected CV-1 cells |
Bioorg Med Chem Lett 8: 2731-6 (1999)
BindingDB Entry DOI: 10.7270/Q2QF8S1M |
More data for this Ligand-Target Pair | |