Found 8 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
PAS domain-containing serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM463484
((S)-3-(2-Methylpyrrolidin-1-yl)-2-phenylquinoxalin...)Show SMILES C[C@H]1CCCN1c1nc2cc(ccc2nc1-c1ccccc1)C(O)=O Show InChI InChI=1S/C20H19N3O2/c1-13-6-5-11-23(13)19-18(14-7-3-2-4-8-14)21-16-10-9-15(20(24)25)12-17(16)22-19/h2-4,7-10,12-13H,5-6,11H2,1H3,(H,24,25)/t13-/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
BioEnergenix LLC
US Patent
| Assay Description Purified PASK (UniProt # Q96RG2; human recombinant N-terminal GST tagged construct, residues 879-1323) from insect cells (final concentration 5 nM) i... |
US Patent US10781185 (2020)
BindingDB Entry DOI: 10.7270/Q2DR2ZKW |
More data for this Ligand-Target Pair | |
PAS domain-containing serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM463516
(3-(2-Methylpyrrolidin-1-yl)-2-phenylquinoxaline-6-...)Show InChI InChI=1S/C20H19N3O2/c1-13-6-5-11-23(13)19-18(14-7-3-2-4-8-14)21-16-10-9-15(20(24)25)12-17(16)22-19/h2-4,7-10,12-13H,5-6,11H2,1H3,(H,24,25) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
BioEnergenix LLC
US Patent
| Assay Description Compound screening was done via the following method. 10 mM stock solution of test compound in DMSO was prepared by dissolving test compound in DMSO ... |
US Patent US10781185 (2020)
BindingDB Entry DOI: 10.7270/Q2DR2ZKW |
More data for this Ligand-Target Pair | |
PAS domain-containing serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM463484
((S)-3-(2-Methylpyrrolidin-1-yl)-2-phenylquinoxalin...)Show SMILES C[C@H]1CCCN1c1nc2cc(ccc2nc1-c1ccccc1)C(O)=O Show InChI InChI=1S/C20H19N3O2/c1-13-6-5-11-23(13)19-18(14-7-3-2-4-8-14)21-16-10-9-15(20(24)25)12-17(16)22-19/h2-4,7-10,12-13H,5-6,11H2,1H3,(H,24,25)/t13-/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
BioEnergenix LLC
US Patent
| Assay Description Compound screening was done via the following method. 10 mM stock solution of test compound in DMSO was prepared by dissolving test compound in DMSO ... |
US Patent US10781185 (2020)
BindingDB Entry DOI: 10.7270/Q2DR2ZKW |
More data for this Ligand-Target Pair | |
PAS domain-containing serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM463484
((S)-3-(2-Methylpyrrolidin-1-yl)-2-phenylquinoxalin...)Show SMILES C[C@H]1CCCN1c1nc2cc(ccc2nc1-c1ccccc1)C(O)=O Show InChI InChI=1S/C20H19N3O2/c1-13-6-5-11-23(13)19-18(14-7-3-2-4-8-14)21-16-10-9-15(20(24)25)12-17(16)22-19/h2-4,7-10,12-13H,5-6,11H2,1H3,(H,24,25)/t13-/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
BioEnergenix LLC
US Patent
| Assay Description Compound screening was done via the following method. 10 mM stock solution of test compound in DMSO was prepared by dissolving test compound in DMSO ... |
US Patent US10781185 (2020)
BindingDB Entry DOI: 10.7270/Q2DR2ZKW |
More data for this Ligand-Target Pair | |
PAS domain-containing serine/threonine-protein kinase [879-1323]
(Homo sapiens (Human)) | BDBM574782
((S)-3-(2-Methylpyrrolidin-1-yl)-2-phenylquinoxalin...)Show SMILES CC1CCCN1c1nc2cc(ccc2nc1-c1ccccc1)C(O)=O |w:1.0| | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Purified PASK (UniProt #Q96RG2; human recombinant N-terminal GST tagged construct, residues 879-1323) from insect cells (final concentration 5 nM) is... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2D79FN2 |
More data for this Ligand-Target Pair | |
PAS domain-containing serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM463516
(3-(2-Methylpyrrolidin-1-yl)-2-phenylquinoxaline-6-...)Show InChI InChI=1S/C20H19N3O2/c1-13-6-5-11-23(13)19-18(14-7-3-2-4-8-14)21-16-10-9-15(20(24)25)12-17(16)22-19/h2-4,7-10,12-13H,5-6,11H2,1H3,(H,24,25) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description The aim of the FRET assay is to determine the inhibition potential of test compounds on targeted kinase. This assay platform provides a homogenous sc... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2D79FN2 |
More data for this Ligand-Target Pair | |
PAS domain-containing serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM574782
((S)-3-(2-Methylpyrrolidin-1-yl)-2-phenylquinoxalin...)Show SMILES CC1CCCN1c1nc2cc(ccc2nc1-c1ccccc1)C(O)=O |w:1.0| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description The aim of the FRET assay is to determine the inhibition potential of test compounds on targeted kinase. This assay platform provides a homogenous sc... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2D79FN2 |
More data for this Ligand-Target Pair | |
PAS domain-containing serine/threonine-protein kinase
(Homo sapiens (Human)) | BDBM574782
((S)-3-(2-Methylpyrrolidin-1-yl)-2-phenylquinoxalin...)Show SMILES CC1CCCN1c1nc2cc(ccc2nc1-c1ccccc1)C(O)=O |w:1.0| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description The aim of the FRET assay is to determine the inhibition potential of test compounds on targeted kinase. This assay platform provides a homogenous sc... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2D79FN2 |
More data for this Ligand-Target Pair | |