Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
C-X-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM228198
(1-{(R)-4-[4-(2-Cyclopropyl-pyrimidin-5-yl)-2-trifl...)Show SMILES CC1CNCC(N1C(=O)Cn1cnc(C)n1)c1sc(cc1-c1cnc(nc1)C1CC1)C(F)(F)F Show InChI InChI=1S/C22H24F3N7OS/c1-12-6-26-9-17(32(12)19(33)10-31-11-29-13(2)30-31)20-16(5-18(34-20)22(23,24)25)15-7-27-21(28-8-15)14-3-4-14/h5,7-8,11-12,14,17,26H,3-4,6,9-10H2,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 5.20 | n/a | n/a | n/a | n/a | 7.4 | n/a |
IDORSIA PHARMACEUTICALS LTD.
US Patent
| Assay Description
The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the... |
US Patent US10047080 (2018)
BindingDB Entry DOI: 10.7270/Q2JQ130F |
More data for this
Ligand-Target Pair | |
C-X-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM228198
(1-{(R)-4-[4-(2-Cyclopropyl-pyrimidin-5-yl)-2-trifl...)Show SMILES CC1CNCC(N1C(=O)Cn1cnc(C)n1)c1sc(cc1-c1cnc(nc1)C1CC1)C(F)(F)F Show InChI InChI=1S/C22H24F3N7OS/c1-12-6-26-9-17(32(12)19(33)10-31-11-29-13(2)30-31)20-16(5-18(34-20)22(23,24)25)15-7-27-21(28-8-15)14-3-4-14/h5,7-8,11-12,14,17,26H,3-4,6,9-10H2,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 462 | n/a | n/a | n/a | n/a | n/a | n/a |
IDORSIA PHARMACEUTICALS LTD.
US Patent
| Assay Description
Stock solutions of test compounds are made up at a concentration of 10 mM in DMSO, and serially diluted in PBS containing 0.5% BSA to concentrations ... |
US Patent US10047080 (2018)
BindingDB Entry DOI: 10.7270/Q2JQ130F |
More data for this
Ligand-Target Pair | |