Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
C-X-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM228186
(2-[3-(1-Hydroxy-ethyl)-[1,2,4]triazol-1-yl]-1-{(R)...)Show SMILES CC1CNCC(N1C(=O)Cn1cnc(CCO)n1)c1sc(cc1-c1cnc(nc1)C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C21H21F6N7O2S/c1-11-5-28-8-14(34(11)17(36)9-33-10-31-16(32-33)2-3-35)18-13(4-15(37-18)20(22,23)24)12-6-29-19(30-7-12)21(25,26)27/h4,6-7,10-11,14,28,35H,2-3,5,8-9H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | 7.4 | n/a |
IDORSIA PHARMACEUTICALS LTD.
US Patent
| Assay Description
The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the... |
US Patent US10047080 (2018)
BindingDB Entry DOI: 10.7270/Q2JQ130F |
More data for this
Ligand-Target Pair | |
C-X-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM228186
(2-[3-(1-Hydroxy-ethyl)-[1,2,4]triazol-1-yl]-1-{(R)...)Show SMILES CC1CNCC(N1C(=O)Cn1cnc(CCO)n1)c1sc(cc1-c1cnc(nc1)C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C21H21F6N7O2S/c1-11-5-28-8-14(34(11)17(36)9-33-10-31-16(32-33)2-3-35)18-13(4-15(37-18)20(22,23)24)12-6-29-19(30-7-12)21(25,26)27/h4,6-7,10-11,14,28,35H,2-3,5,8-9H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 564 | n/a | n/a | n/a | n/a | n/a | n/a |
IDORSIA PHARMACEUTICALS LTD.
US Patent
| Assay Description
Stock solutions of test compounds are made up at a concentration of 10 mM in DMSO, and serially diluted in PBS containing 0.5% BSA to concentrations ... |
US Patent US10047080 (2018)
BindingDB Entry DOI: 10.7270/Q2JQ130F |
More data for this
Ligand-Target Pair | |