Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
C-X-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM228184
(2-(3-Hydroxymethyl-[1,2,4]triazol-1-yl)-1-{(R)-2-m...)Show SMILES CC1CNCC(N1C(=O)Cn1cnc(CO)n1)c1sc(cc1-c1cnc(nc1)C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C20H19F6N7O2S/c1-10-3-27-6-13(33(10)16(35)7-32-9-30-15(8-34)31-32)17-12(2-14(36-17)19(21,22)23)11-4-28-18(29-5-11)20(24,25)26/h2,4-5,9-10,13,27,34H,3,6-8H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 5.20 | n/a | n/a | n/a | n/a | 7.4 | n/a |
IDORSIA PHARMACEUTICALS LTD.
US Patent
| Assay Description
The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the... |
US Patent US10047080 (2018)
BindingDB Entry DOI: 10.7270/Q2JQ130F |
More data for this
Ligand-Target Pair | |
C-X-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM228184
(2-(3-Hydroxymethyl-[1,2,4]triazol-1-yl)-1-{(R)-2-m...)Show SMILES CC1CNCC(N1C(=O)Cn1cnc(CO)n1)c1sc(cc1-c1cnc(nc1)C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C20H19F6N7O2S/c1-10-3-27-6-13(33(10)16(35)7-32-9-30-15(8-34)31-32)17-12(2-14(36-17)19(21,22)23)11-4-28-18(29-5-11)20(24,25)26/h2,4-5,9-10,13,27,34H,3,6-8H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 809 | n/a | n/a | n/a | n/a | n/a | n/a |
IDORSIA PHARMACEUTICALS LTD.
US Patent
| Assay Description
Stock solutions of test compounds are made up at a concentration of 10 mM in DMSO, and serially diluted in PBS containing 0.5% BSA to concentrations ... |
US Patent US10047080 (2018)
BindingDB Entry DOI: 10.7270/Q2JQ130F |
More data for this
Ligand-Target Pair | |