Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
C-X-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM228178
(1-(2-{(R)-2-Methyl-4-[2-trifluoromethyl-4-(2-trifl...)Show SMILES CC1CNCC(N1C(=O)Cn1cnc(n1)C(N)=O)c1sc(cc1-c1cnc(nc1)C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C20H18F6N8O2S/c1-9-3-28-6-12(34(9)14(35)7-33-8-31-17(32-33)16(27)36)15-11(2-13(37-15)19(21,22)23)10-4-29-18(30-5-10)20(24,25)26/h2,4-5,8-9,12,28H,3,6-7H2,1H3,(H2,27,36) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | 7.4 | n/a |
IDORSIA PHARMACEUTICALS LTD.
US Patent
| Assay Description
The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the... |
US Patent US10047080 (2018)
BindingDB Entry DOI: 10.7270/Q2JQ130F |
More data for this
Ligand-Target Pair | |
C-X-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM228178
(1-(2-{(R)-2-Methyl-4-[2-trifluoromethyl-4-(2-trifl...)Show SMILES CC1CNCC(N1C(=O)Cn1cnc(n1)C(N)=O)c1sc(cc1-c1cnc(nc1)C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C20H18F6N8O2S/c1-9-3-28-6-12(34(9)14(35)7-33-8-31-17(32-33)16(27)36)15-11(2-13(37-15)19(21,22)23)10-4-29-18(30-5-10)20(24,25)26/h2,4-5,8-9,12,28H,3,6-7H2,1H3,(H2,27,36) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 1.71E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
IDORSIA PHARMACEUTICALS LTD.
US Patent
| Assay Description
Stock solutions of test compounds are made up at a concentration of 10 mM in DMSO, and serially diluted in PBS containing 0.5% BSA to concentrations ... |
US Patent US10047080 (2018)
BindingDB Entry DOI: 10.7270/Q2JQ130F |
More data for this
Ligand-Target Pair | |