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Target
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Marvin 2D Structure
The following exact ligands are found in BindingDB
Wt: 304.7
BDBM510498
Wt: 304.7
BDBM510506
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target/Host
(Institution)
Ligand
Target/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
k
off
s
-1
k
on
M
-1
s
-1
pH
Temp
°C
Phosphatidylinositol 3-kinase catalytic subunit type 3
(Homo sapiens (Human))
BDBM510506
(6-(2-chlorophenyl)-4-[(3R)-3-methylmorpholin-4-yl]...)
Show SMILES
C[C@@H]1COCCN1c1cc([nH]c(=O)c1)-c1ccccc1Cl |r|
Show InChI
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
US Patent
n/a
n/a
7
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...
Citation and Details
BindingDB Entry DOI:
10.7270/Q2FB562C
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3
(Homo sapiens (Human))
BDBM510506
(6-(2-chlorophenyl)-4-[(3R)-3-methylmorpholin-4-yl]...)
Show SMILES
C[C@@H]1COCCN1c1cc([nH]c(=O)c1)-c1ccccc1Cl |r|
Show InChI
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
n/a
n/a
7
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Citation and Details
BindingDB Entry DOI:
10.7270/Q27948MS
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3
(Homo sapiens (Human))
BDBM510498
(6-(2-chlorophenyl)-4-(3-methylmorpholin-4-yl)-1H-p...)
Show SMILES
CC1COCCN1c1cc([nH]c(=O)c1)-c1ccccc1Cl
Show InChI
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
n/a
n/a
10
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Citation and Details
BindingDB Entry DOI:
10.7270/Q27948MS
More data for this
Ligand-Target Pair
Phosphatidylinositol 3-kinase catalytic subunit type 3
(Homo sapiens (Human))
BDBM510498
(6-(2-chlorophenyl)-4-(3-methylmorpholin-4-yl)-1H-p...)
Show SMILES
CC1COCCN1c1cc([nH]c(=O)c1)-c1ccccc1Cl
Show InChI
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
PC cid
PC sid
UniChem
US Patent
n/a
n/a
10
n/a
n/a
n/a
n/a
n/a
n/a
TBA
Assay Description
Dilution series of compounds of the invention were prepared in DMSO at 100 times the final assay concentration (n1=n0/3 in 10 points). The compounds ...
Citation and Details
BindingDB Entry DOI:
10.7270/Q2FB562C
More data for this
Ligand-Target Pair