Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 377.4 BDBM233843

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM233843 (US9353081, 47) Show SMILES CCC(=O)N[C@@H]1[C@@H](C)CCc2c1cncc2-c1ccc2N(C)C(=O)CCc2c1 |r| Show InChI InChI=1S/C23H27N3O2/c1-4-21(27)25-23-14(2)5-8-17-18(12-24-13-19(17)23)15-6-9-20-16(11-15)7-10-22(28)26(20)3/h6,9,11-14,23H,4-5,7-8,10H2,1-3H3,(H,25,27)/t14-,23+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.82E+3	n/a	n/a	n/a	37
Hoffmann-La Roche Inc. US Patent					Assay Description The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...				US Patent US9353081 (2016) BindingDB Entry DOI: 10.7270/Q2ZW1JT1
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