Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Cytochrome P450 11B1, mitochondrial
(Homo sapiens (Human)) | BDBM233850
(US9353081, 54)Show SMILES CCC(=O)N[C@H]1[C@H](F)CCc2c1cncc2-c1cc2CCC(=O)N(C)c2cc1F |r| Show InChI InChI=1S/C22H23F2N3O2/c1-3-20(28)26-22-16-11-25-10-15(13(16)5-6-17(22)23)14-8-12-4-7-21(29)27(2)19(12)9-18(14)24/h8-11,17,22H,3-7H2,1-2H3,(H,26,28)/t17-,22-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | n/a | n/a | 2.39E+3 | n/a | n/a | n/a | 37 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita... |
US Patent US9353081 (2016)
BindingDB Entry DOI: 10.7270/Q2ZW1JT1 |
More data for this Ligand-Target Pair | |
Cytochrome P450 11B2, mitochondrial
(Homo sapiens (Human)) | BDBM233850
(US9353081, 54)Show SMILES CCC(=O)N[C@H]1[C@H](F)CCc2c1cncc2-c1cc2CCC(=O)N(C)c2cc1F |r| Show InChI InChI=1S/C22H23F2N3O2/c1-3-20(28)26-22-16-11-25-10-15(13(16)5-6-17(22)23)14-8-12-4-7-21(29)27(2)19(12)9-18(14)24/h8-11,17,22H,3-7H2,1-2H3,(H,26,28)/t17-,22-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | n/a | n/a | 38.8 | n/a | n/a | n/a | 37 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita... |
US Patent US9353081 (2016)
BindingDB Entry DOI: 10.7270/Q2ZW1JT1 |
More data for this Ligand-Target Pair | |