Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 247.2 BDBM408862

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Asialoglycoprotein receptor 1 (Homo sapiens (Human))	BDBM408862 (US10376531, Compound 25 | US10813942, Compound 25) Show SMILES CCC(=O)N[C@H]1[C@H]2OC[C@](CO)(O2)[C@H](O)[C@@H]1O |r| Show InChI InChI=1S/C10H17NO6/c1-2-5(13)11-6-7(14)8(15)10(3-12)4-16-9(6)17-10/h6-9,12,14-15H,2-4H2,1H3,(H,11,13)/t6-,7-,8-,9?,10+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...				US Patent US10813942 (2020) BindingDB Entry DOI: 10.7270/Q28G8PSJ
					More data for this Ligand-Target Pair
Asialoglycoprotein receptor 1 (Homo sapiens (Human))	BDBM408862 (US10376531, Compound 25 | US10813942, Compound 25) Show SMILES CCC(=O)N[C@H]1[C@H]2OC[C@](CO)(O2)[C@H](O)[C@@H]1O |r| Show InChI InChI=1S/C10H17NO6/c1-2-5(13)11-6-7(14)8(15)10(3-12)4-16-9(6)17-10/h6-9,12,14-15H,2-4H2,1H3,(H,11,13)/t6-,7-,8-,9?,10+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200...				US Patent US10376531 (2019) BindingDB Entry DOI: 10.7270/Q2542QZJ
					More data for this Ligand-Target Pair