Found 3 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Cytochrome P450 11B2, mitochondrial
(Homo sapiens (Human)) | BDBM191908
(US9187429, 43)Show InChI InChI=1S/C18H17F3N2O/c1-2-18(24)23-17-5-3-4-10-12(8-22-9-13(10)17)11-6-15(20)16(21)7-14(11)19/h6-9,17H,2-5H2,1H3,(H,23,24) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
Roche Pharma Research and Early Development (pRED)
Curated by ChEMBL
| Assay Description Inhibition of human CYP11B2 expressed in human renal leiomyoblastoma cells using 11-deoxycorticosterone as substrate assessed as formation of aldoste... |
J Med Chem 58: 8054-65 (2015)
Article DOI: 10.1021/acs.jmedchem.5b00851 BindingDB Entry DOI: 10.7270/Q2K0763C |
More data for this Ligand-Target Pair | |
Cytochrome P450 11B1, mitochondrial
(Homo sapiens (Human)) | BDBM191908
(US9187429, 43)Show InChI InChI=1S/C18H17F3N2O/c1-2-18(24)23-17-5-3-4-10-12(8-22-9-13(10)17)11-6-15(20)16(21)7-14(11)19/h6-9,17H,2-5H2,1H3,(H,23,24) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| US Patent
| n/a | n/a | n/a | n/a | 1.15E+3 | n/a | n/a | n/a | n/a |
HOFFMANN-LA ROCHE INC.
US Patent
| Assay Description G-402 cells can be obtained from ATCC(CRL-1440) and were originally
derived from a renal leiomyoblastoma. The expression plasmids contains
the ORF ... |
US Patent US9187429 (2015)
BindingDB Entry DOI: 10.7270/Q2668C04 |
More data for this Ligand-Target Pair | |
Cytochrome P450 11B2, mitochondrial
(Homo sapiens (Human)) | BDBM191908
(US9187429, 43)Show InChI InChI=1S/C18H17F3N2O/c1-2-18(24)23-17-5-3-4-10-12(8-22-9-13(10)17)11-6-15(20)16(21)7-14(11)19/h6-9,17H,2-5H2,1H3,(H,23,24) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| US Patent
| n/a | n/a | n/a | n/a | 27 | n/a | n/a | n/a | n/a |
HOFFMANN-LA ROCHE INC.
US Patent
| Assay Description G-402 cells can be obtained from ATCC(CRL-1440) and were originally
derived from a renal leiomyoblastoma. The expression plasmids contains
the ORF ... |
US Patent US9187429 (2015)
BindingDB Entry DOI: 10.7270/Q2668C04 |
More data for this Ligand-Target Pair | |