Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Cytochrome P450 11B1, mitochondrial
(Homo sapiens (Human)) | BDBM233815
(US9353081, 13)Show SMILES CCC(=O)NCCN1CCCc2c1cncc2-c1ccc2N(C)C(=O)CCc2c1 Show InChI InChI=1S/C23H28N4O2/c1-3-22(28)25-10-12-27-11-4-5-18-19(14-24-15-21(18)27)16-6-8-20-17(13-16)7-9-23(29)26(20)2/h6,8,13-15H,3-5,7,9-12H2,1-2H3,(H,25,28) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | n/a | n/a | 1.81E+3 | n/a | n/a | n/a | 37 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita... |
US Patent US9353081 (2016)
BindingDB Entry DOI: 10.7270/Q2ZW1JT1 |
More data for this Ligand-Target Pair | |
Cytochrome P450 11B2, mitochondrial
(Homo sapiens (Human)) | BDBM233815
(US9353081, 13)Show SMILES CCC(=O)NCCN1CCCc2c1cncc2-c1ccc2N(C)C(=O)CCc2c1 Show InChI InChI=1S/C23H28N4O2/c1-3-22(28)25-10-12-27-11-4-5-18-19(14-24-15-21(18)27)16-6-8-20-17(13-16)7-9-23(29)26(20)2/h6,8,13-15H,3-5,7,9-12H2,1-2H3,(H,25,28) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | n/a | n/a | 14 | n/a | n/a | n/a | 37 |
Hoffmann-La Roche Inc.
US Patent
| Assay Description The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita... |
US Patent US9353081 (2016)
BindingDB Entry DOI: 10.7270/Q2ZW1JT1 |
More data for this Ligand-Target Pair | |