Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 427.9 BDBM50417492

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 2 (Homo sapiens (Human))	BDBM50417492 (CHEMBL1288257) Show SMILES CCC(C(=O)Nc1ccc(N2CCC(CC2)NCC2CC2)c(Cl)c1)c1ncccn1 Show InChI InChI=1S/C23H30ClN5O/c1-2-19(22-25-10-3-11-26-22)23(30)28-18-6-7-21(20(24)14-18)29-12-8-17(9-13-29)27-15-16-4-5-16/h3,6-7,10-11,14,16-17,19,27H,2,4-5,8-9,12-13,15H2,1H3,(H,28,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	631	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human NPY Y2 receptor in KAN-TS cells by [35]GTPgammaS assay				Bioorg Med Chem Lett 20: 7341-4 (2010) Article DOI: 10.1016/j.bmcl.2010.10.065 BindingDB Entry DOI: 10.7270/Q2BV7HWV
					More data for this Ligand-Target Pair