Found 5 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Bombesin receptor subtype-3
(Homo sapiens (Human)) | BDBM50314985
(1-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)et...)Show InChI InChI=1S/C22H33N3/c1-4-22(2,3)16-19-17-23-21(24-19)13-10-18-8-11-20(12-9-18)25-14-6-5-7-15-25/h8-9,11-12,17H,4-7,10,13-16H2,1-3H3,(H,23,24) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [125I]D-Tyr6-betaAla11-Phe13-Nle14-bombesin from human BRS-3 expressed in NFAT-CHO cells after 2 hrs by scintillation counting |
Bioorg Med Chem Lett 20: 2074-7 (2010)
Article DOI: 10.1016/j.bmcl.2010.02.076 BindingDB Entry DOI: 10.7270/Q2XW4JX6 |
More data for this Ligand-Target Pair | |
Bombesin receptor subtype-3
(Mus musculus) | BDBM50314985
(1-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)et...)Show InChI InChI=1S/C22H33N3/c1-4-22(2,3)16-19-17-23-21(24-19)13-10-18-8-11-20(12-9-18)25-14-6-5-7-15-25/h8-9,11-12,17H,4-7,10,13-16H2,1-3H3,(H,23,24) | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 133 | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Agonist activity at mouse BRS-3 expressed in HEK293 cells coexpressing AEQ over 10 mins by aequorin bioluminescence assay relative to D-Tyr6-betaAla1... |
Bioorg Med Chem Lett 20: 2074-7 (2010)
Article DOI: 10.1016/j.bmcl.2010.02.076 BindingDB Entry DOI: 10.7270/Q2XW4JX6 |
More data for this Ligand-Target Pair | |
Bombesin receptor subtype-3
(Mus musculus) | BDBM50314985
(1-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)et...)Show InChI InChI=1S/C22H33N3/c1-4-22(2,3)16-19-17-23-21(24-19)13-10-18-8-11-20(12-9-18)25-14-6-5-7-15-25/h8-9,11-12,17H,4-7,10,13-16H2,1-3H3,(H,23,24) | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 28 | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Agonist activity at mouse BRS-3 expressed in HEK293 cells coexpressing AEQ over 10 mins by aequorin bioluminescence assay |
Bioorg Med Chem Lett 20: 2074-7 (2010)
Article DOI: 10.1016/j.bmcl.2010.02.076 BindingDB Entry DOI: 10.7270/Q2XW4JX6 |
More data for this Ligand-Target Pair | |
Bombesin receptor subtype-3
(Homo sapiens (Human)) | BDBM50314985
(1-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)et...)Show InChI InChI=1S/C22H33N3/c1-4-22(2,3)16-19-17-23-21(24-19)13-10-18-8-11-20(12-9-18)25-14-6-5-7-15-25/h8-9,11-12,17H,4-7,10,13-16H2,1-3H3,(H,23,24) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 171 | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Agonist activity at human BRS-3 expressed in HEK293 cells coexpressing AEQ over 10 mins by aequorin bioluminescence assay |
Bioorg Med Chem Lett 20: 2074-7 (2010)
Article DOI: 10.1016/j.bmcl.2010.02.076 BindingDB Entry DOI: 10.7270/Q2XW4JX6 |
More data for this Ligand-Target Pair | |
Bombesin receptor subtype-3
(Homo sapiens (Human)) | BDBM50314985
(1-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)et...)Show InChI InChI=1S/C22H33N3/c1-4-22(2,3)16-19-17-23-21(24-19)13-10-18-8-11-20(12-9-18)25-14-6-5-7-15-25/h8-9,11-12,17H,4-7,10,13-16H2,1-3H3,(H,23,24) | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 108 | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Agonist activity at human BRS-3 expressed in HEK293 cells coexpressing AEQ over 10 mins by aequorin bioluminescence assay relative to D-Tyr6-betaAla1... |
Bioorg Med Chem Lett 20: 2074-7 (2010)
Article DOI: 10.1016/j.bmcl.2010.02.076 BindingDB Entry DOI: 10.7270/Q2XW4JX6 |
More data for this Ligand-Target Pair | |