Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 432.5 BDBM50437426

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Probable G-protein coupled receptor 142 (Homo sapiens (Human))	BDBM50437426 (CHEMBL2409029) Show SMILES CCC(C)c1c(cnn1-c1ncc(C)c(n1)-c1cccs1)C(=O)NCc1ccncc1 Show InChI InChI=1S/C23H24N6OS/c1-4-15(2)21-18(22(30)25-13-17-7-9-24-10-8-17)14-27-29(21)23-26-12-16(3)20(28-23)19-6-5-11-31-19/h5-12,14-15H,4,13H2,1-3H3,(H,25,30)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a
Daiichi Sankyo Co., Ltd. Curated by ChEMBL					Assay Description Agonist activity at human GPR142 transfected in HEK293 cells after 1 hr by inositol phosphate accumulation assay				ACS Med Chem Lett 4: 790-4 (2013) Article DOI: 10.1021/ml400186z BindingDB Entry DOI: 10.7270/Q24J0GHW
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