Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 554.6 BDBM102388

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM102388 (US9695149, 213) Show SMILES CCC(CC)(Cc1nc2ccc(OCc3ccn(C)n3)cc2n1Cc1cccc(c1)-c1cnc(OC)nc1)C(O)=O Show InChI InChI=1S/C31H34N6O4/c1-5-31(6-2,29(38)39)16-28-34-26-11-10-25(41-20-24-12-13-36(3)35-24)15-27(26)37(28)19-21-8-7-9-22(14-21)23-17-32-30(40-4)33-18-23/h7-15,17-18H,5-6,16,19-20H2,1-4H3,(H,38,39)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	940	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9695149 (2017) BindingDB Entry DOI: 10.7270/Q2Q52MSC
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