Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 626.6 BDBM102305

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM102305 (US9695149, 194) Show SMILES CCC(CC)(Cc1nc2ccc(OCc3ncc(C)cc3F)cc2n1Cc1ccc(cc1)N1CCC(CC1)C(F)(F)F)C(O)=O Show InChI InChI=1S/C34H38F4N4O3/c1-4-33(5-2,32(43)44)18-31-40-28-11-10-26(45-21-29-27(35)16-22(3)19-39-29)17-30(28)42(31)20-23-6-8-25(9-7-23)41-14-12-24(13-15-41)34(36,37)38/h6-11,16-17,19,24H,4-5,12-15,18,20-21H2,1-3H3,(H,43,44)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9695149 (2017) BindingDB Entry DOI: 10.7270/Q2Q52MSC
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