Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 489.6 BDBM50352390

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 2 (Homo sapiens (Human))	BDBM50352390 (CHEMBL1823575) Show SMILES CCC(CC)C(=O)Nc1ccc(N2CCN(CC2)C(C(=O)N(CC)CC)c2ccccc2)c(c1)C#N Show InChI InChI=1S/C29H39N5O2/c1-5-22(6-2)28(35)31-25-14-15-26(24(20-25)21-30)33-16-18-34(19-17-33)27(23-12-10-9-11-13-23)29(36)32(7-3)8-4/h9-15,20,22,27H,5-8,16-19H2,1-4H3,(H,31,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Displacement of [125I]PYY from human NPY Y2 receptor expressed endogenously in KAN-Ts cells by scintillation counting				Bioorg Med Chem Lett 21: 5552-6 (2011) Article DOI: 10.1016/j.bmcl.2011.06.136 BindingDB Entry DOI: 10.7270/Q2R49R5K
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 2 (Homo sapiens (Human))	BDBM50352390 (CHEMBL1823575) Show SMILES CCC(CC)C(=O)Nc1ccc(N2CCN(CC2)C(C(=O)N(CC)CC)c2ccccc2)c(c1)C#N Show InChI InChI=1S/C29H39N5O2/c1-5-22(6-2)28(35)31-25-14-15-26(24(20-25)21-30)33-16-18-34(19-17-33)27(23-12-10-9-11-13-23)29(36)32(7-3)8-4/h9-15,20,22,27H,5-8,16-19H2,1-4H3,(H,31,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Displacement of [125I]PYY from human NPY Y2 receptor expressed endogenously in KAN-Ts cells by scintillation counting				Bioorg Med Chem Lett 21: 5552-6 (2011) Article DOI: 10.1016/j.bmcl.2011.06.136 BindingDB Entry DOI: 10.7270/Q2R49R5K
					More data for this Ligand-Target Pair