Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 617.7 BDBM50469820

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50469820 (CHEMBL339958) Show SMILES CCC(CC)CNC(=O)c1ccc2c(CC(C)C)cn(Cc3ccc(cc3OC)C(=O)NS(=O)(=O)c3ccccc3C)c2c1 Show InChI InChI=1S/C35H43N3O5S/c1-7-25(8-2)20-36-34(39)26-15-16-30-29(17-23(3)4)22-38(31(30)18-26)21-28-14-13-27(19-32(28)43-6)35(40)37-44(41,42)33-12-10-9-11-24(33)5/h9-16,18-19,22-23,25H,7-8,17,20-21H2,1-6H3,(H,36,39)(H,37,40)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Group Curated by ChEMBL					Assay Description Binding affinity against leukotriene receptor (LTD4) from guinea pig lung parenchymal membranes using [3H]LTD4 as radio ligand				J Med Chem 36: 394-409 (1993) Article DOI: 10.1021/jm00055a011 BindingDB Entry DOI: 10.7270/Q2FX7D5T
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