Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 643.8 BDBM50469809

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50469809 (CHEMBL133790) Show SMILES CCC(CC)CNC(=O)c1ccc2c(CC3CCCC3)cn(Cc3ccc(cc3OC)C(=O)NS(=O)(=O)c3ccccc3C)c2c1 Show InChI InChI=1S/C37H45N3O5S/c1-5-26(6-2)22-38-36(41)28-17-18-32-31(19-27-12-8-9-13-27)24-40(33(32)20-28)23-30-16-15-29(21-34(30)45-4)37(42)39-46(43,44)35-14-10-7-11-25(35)3/h7,10-11,14-18,20-21,24,26-27H,5-6,8-9,12-13,19,22-23H2,1-4H3,(H,38,41)(H,39,42)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Group Curated by ChEMBL					Assay Description Binding affinity against leukotriene receptor (LTD4) from guinea pig lung parenchymal membranes using [3H]LTD4 as radio ligand				J Med Chem 36: 394-409 (1993) Article DOI: 10.1021/jm00055a011 BindingDB Entry DOI: 10.7270/Q2FX7D5T
					More data for this Ligand-Target Pair