Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 355.4 BDBM50521958

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50521958 (CHEMBL4440299) Show SMILES CCC(CC)c1nn(-c2ccc(F)cc2)c2nc(CC)cc(C(O)=O)c12 Show InChI InChI=1S/C20H22FN3O2/c1-4-12(5-2)18-17-16(20(25)26)11-14(6-3)22-19(17)24(23-18)15-9-7-13(21)8-10-15/h7-12H,4-6H2,1-3H3,(H,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	n/a	1.53E+3	n/a	n/a	n/a	n/a
Okayama University Curated by ChEMBL					Assay Description Transactivation of human GAL4-fused PPARalpha LBD expressed in human HepG2 cells after 24 hrs by renilla luciferase reporter gene assay				Bioorg Med Chem Lett 29: 2124-2128 (2019) Article DOI: 10.1016/j.bmcl.2019.06.062 BindingDB Entry DOI: 10.7270/Q23N26T3
					More data for this Ligand-Target Pair				3D Structure (crystal)