Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 443.9 BDBM50210728

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Chymase (Homo sapiens (Human))	BDBM50210728 (6-(5-chloro-2-methoxybenzyl)-3,7-dioxo-N-(1-phenyl...) Show SMILES CCC(NC(=O)N1CC(=O)NCC(Cc2cc(Cl)ccc2OC)C1=O)c1ccccc1 Show InChI InChI=1S/C23H26ClN3O4/c1-3-19(15-7-5-4-6-8-15)26-23(30)27-14-21(28)25-13-17(22(27)29)11-16-12-18(24)9-10-20(16)31-2/h4-10,12,17,19H,3,11,13-14H2,1-2H3,(H,25,28)(H,26,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Asubio Pharma Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human recombinant chymase				Bioorg Med Chem Lett 17: 3435-9 (2007) Article DOI: 10.1016/j.bmcl.2007.03.085 BindingDB Entry DOI: 10.7270/Q2MK6CKH
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