Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 391.4 BDBM50264383

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50264383 (5-(5-ethyl-1-methyl-2-oxo-5-(thiophen-2-yl)-1,2,3,...) Show SMILES CCC1(OCC(=O)N(C)c2ccc(cc12)-c1ccc(C#N)n1C)c1cccs1 Show InChI InChI=1S/C22H21N3O2S/c1-4-22(20-6-5-11-28-20)17-12-15(18-10-8-16(13-23)24(18)2)7-9-19(17)25(3)21(26)14-27-22/h5-12H,4,14H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at progesterone receptor assessed as progesterone-induced alkaline phosphatase activity in human T47D cells				Bioorg Med Chem Lett 18: 5015-7 (2008) Article DOI: 10.1016/j.bmcl.2008.08.015 BindingDB Entry DOI: 10.7270/Q25B03D7
					More data for this Ligand-Target Pair