Found 6 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Metabotropic glutamate receptor 3
(Rattus norvegicus (Rat)) | BDBM50072169
((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...)Show SMILES CCCCC[C@@H]1[C@@H]([C@H]1C(N)(CC1c2ccccc2Oc2ccccc12)C(O)=O)C(O)=O Show InChI InChI=1S/C25H29NO5/c1-2-3-4-11-17-21(23(27)28)22(17)25(26,24(29)30)14-18-15-9-5-7-12-19(15)31-20-13-8-6-10-16(18)20/h5-10,12-13,17-18,21-22H,2-4,11,14,26H2,1H3,(H,27,28)(H,29,30)/t17-,21+,22+,25?/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigación Lilly, SA
Curated by ChEMBL
| Assay Description Antagonistic activity against metabotropic glutamate receptor 3 (mGluR3) was evaluated |
Bioorg Med Chem Lett 8: 2849-54 (1999)
BindingDB Entry DOI: 10.7270/Q2Z0379C |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 8
(Homo sapiens (Human)) | BDBM50072169
((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...)Show SMILES CCCCC[C@@H]1[C@@H]([C@H]1C(N)(CC1c2ccccc2Oc2ccccc12)C(O)=O)C(O)=O Show InChI InChI=1S/C25H29NO5/c1-2-3-4-11-17-21(23(27)28)22(17)25(26,24(29)30)14-18-15-9-5-7-12-19(15)31-20-13-8-6-10-16(18)20/h5-10,12-13,17-18,21-22H,2-4,11,14,26H2,1H3,(H,27,28)(H,29,30)/t17-,21+,22+,25?/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 340 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigación Lilly, SA
Curated by ChEMBL
| Assay Description Antagonistic activity against metabotropic glutamate receptor 8 (mGluR8) was evaluated |
Bioorg Med Chem Lett 8: 2849-54 (1999)
BindingDB Entry DOI: 10.7270/Q2Z0379C |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 7
(Homo sapiens (Human)) | BDBM50072169
((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...)Show SMILES CCCCC[C@@H]1[C@@H]([C@H]1C(N)(CC1c2ccccc2Oc2ccccc12)C(O)=O)C(O)=O Show InChI InChI=1S/C25H29NO5/c1-2-3-4-11-17-21(23(27)28)22(17)25(26,24(29)30)14-18-15-9-5-7-12-19(15)31-20-13-8-6-10-16(18)20/h5-10,12-13,17-18,21-22H,2-4,11,14,26H2,1H3,(H,27,28)(H,29,30)/t17-,21+,22+,25?/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 7.61E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigación Lilly, SA
Curated by ChEMBL
| Assay Description Antagonistic activity against metabotropic glutamate receptor 7 (mGluR7) was evaluated |
Bioorg Med Chem Lett 8: 2849-54 (1999)
BindingDB Entry DOI: 10.7270/Q2Z0379C |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 4
(Homo sapiens (Human)) | BDBM50072169
((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...)Show SMILES CCCCC[C@@H]1[C@@H]([C@H]1C(N)(CC1c2ccccc2Oc2ccccc12)C(O)=O)C(O)=O Show InChI InChI=1S/C25H29NO5/c1-2-3-4-11-17-21(23(27)28)22(17)25(26,24(29)30)14-18-15-9-5-7-12-19(15)31-20-13-8-6-10-16(18)20/h5-10,12-13,17-18,21-22H,2-4,11,14,26H2,1H3,(H,27,28)(H,29,30)/t17-,21+,22+,25?/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 9.45E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigación Lilly, SA
Curated by ChEMBL
| Assay Description Antagonistic activity against metabotropic glutamate receptor 4 (mGluR4) was evaluated |
Bioorg Med Chem Lett 8: 2849-54 (1999)
BindingDB Entry DOI: 10.7270/Q2Z0379C |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 1
(Homo sapiens (Human)) | BDBM50072169
((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...)Show SMILES CCCCC[C@@H]1[C@@H]([C@H]1C(N)(CC1c2ccccc2Oc2ccccc12)C(O)=O)C(O)=O Show InChI InChI=1S/C25H29NO5/c1-2-3-4-11-17-21(23(27)28)22(17)25(26,24(29)30)14-18-15-9-5-7-12-19(15)31-20-13-8-6-10-16(18)20/h5-10,12-13,17-18,21-22H,2-4,11,14,26H2,1H3,(H,27,28)(H,29,30)/t17-,21+,22+,25?/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigación Lilly, SA
Curated by ChEMBL
| Assay Description Antagonistic activity against metabotropic glutamate receptor 1 (mGluR1) was evaluated |
Bioorg Med Chem Lett 8: 2849-54 (1999)
BindingDB Entry DOI: 10.7270/Q2Z0379C |
More data for this Ligand-Target Pair | |
Metabotropic glutamate receptor 5
(Homo sapiens (Human)) | BDBM50072169
((1S,2S,3S)-2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl...)Show SMILES CCCCC[C@@H]1[C@@H]([C@H]1C(N)(CC1c2ccccc2Oc2ccccc12)C(O)=O)C(O)=O Show InChI InChI=1S/C25H29NO5/c1-2-3-4-11-17-21(23(27)28)22(17)25(26,24(29)30)14-18-15-9-5-7-12-19(15)31-20-13-8-6-10-16(18)20/h5-10,12-13,17-18,21-22H,2-4,11,14,26H2,1H3,(H,27,28)(H,29,30)/t17-,21+,22+,25?/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Centro de Investigación Lilly, SA
Curated by ChEMBL
| Assay Description Antagonistic activity against metabotropic glutamate receptor 5 (mGluR5) was evaluated |
Bioorg Med Chem Lett 8: 2849-54 (1999)
BindingDB Entry DOI: 10.7270/Q2Z0379C |
More data for this Ligand-Target Pair | |