Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 322.4 BDBM50210060

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50210060 (CHEMBL3885118) Show SMILES CCCCCC(CC(=O)CCc1ccc(OC)c(OC)c1)OC Show InChI InChI=1S/C19H30O4/c1-5-6-7-8-17(21-2)14-16(20)11-9-15-10-12-18(22-3)19(13-15)23-4/h10,12-13,17H,5-9,11,14H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Mansoura University Curated by ChEMBL					Assay Description Inhibition of recombinant C-terminal His-tagged human LTA4H aminopeptidase activity expressed in Escherichia coli using L-alanine-4-nitro-anilide hyd...				Bioorg Med Chem 25: 1277-1285 (2017) Article DOI: 10.1016/j.bmc.2016.12.048 BindingDB Entry DOI: 10.7270/Q2SJ1NMK
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50210060 (CHEMBL3885118) Show SMILES CCCCCC(CC(=O)CCc1ccc(OC)c(OC)c1)OC Show InChI InChI=1S/C19H30O4/c1-5-6-7-8-17(21-2)14-16(20)11-9-15-10-12-18(22-3)19(13-15)23-4/h10,12-13,17H,5-9,11,14H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Mansoura University Curated by ChEMBL					Assay Description Inhibition of recombinant C-terminal His-tagged human LTA4H epoxide hydrolase activity expressed in Escherichia coli assessed as reduction in LTB4 pr...				Bioorg Med Chem 25: 1277-1285 (2017) Article DOI: 10.1016/j.bmc.2016.12.048 BindingDB Entry DOI: 10.7270/Q2SJ1NMK
					More data for this Ligand-Target Pair