Found 4 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Putative P2Y purinoceptor 10
(Homo sapiens (Human)) | BDBM50096435
(CHEMBL3577163)Show SMILES CCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)COP(O)(=O)O[C@@H](C)[C@H](N)C(O)=O |r| Show InChI InChI=1S/C23H44NO9P/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-21(26)31-17-20(25)18-32-34(29,30)33-19(2)22(24)23(27)28/h8-9,19-20,22,25H,3-7,10-18,24H2,1-2H3,(H,27,28)(H,29,30)/b9-8-/t19-,20+,22-/m0/s1 | UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 2.04E+3 | n/a | n/a | n/a | n/a |
The University of Tokyo
Curated by ChEMBL
| Assay Description Agonist activity at P2Y10 (unknown origin) transfected in HEK293A cells after 1 hr by TGFalpha shedding assay |
J Med Chem 58: 4204-19 (2015)
Article DOI: 10.1021/jm5020082 BindingDB Entry DOI: 10.7270/Q2Q81FTD |
More data for this Ligand-Target Pair | |
Probable G-protein coupled receptor 174
(Homo sapiens (Human)) | BDBM50096435
(CHEMBL3577163)Show SMILES CCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)COP(O)(=O)O[C@@H](C)[C@H](N)C(O)=O |r| Show InChI InChI=1S/C23H44NO9P/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-21(26)31-17-20(25)18-32-34(29,30)33-19(2)22(24)23(27)28/h8-9,19-20,22,25H,3-7,10-18,24H2,1-2H3,(H,27,28)(H,29,30)/b9-8-/t19-,20+,22-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 580 | n/a | n/a | n/a | n/a |
The University of Tokyo
Curated by ChEMBL
| Assay Description Agonist activity at GPR174 (unknown origin) transfected in HEK293FT cells after 1 hr by TGFalpha shedding assay |
J Med Chem 58: 4204-19 (2015)
Article DOI: 10.1021/jm5020082 BindingDB Entry DOI: 10.7270/Q2Q81FTD |
More data for this Ligand-Target Pair | |
Putative P2Y purinoceptor 10
(Homo sapiens (Human)) | BDBM50096435
(CHEMBL3577163)Show SMILES CCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)COP(O)(=O)O[C@@H](C)[C@H](N)C(O)=O |r| Show InChI InChI=1S/C23H44NO9P/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-21(26)31-17-20(25)18-32-34(29,30)33-19(2)22(24)23(27)28/h8-9,19-20,22,25H,3-7,10-18,24H2,1-2H3,(H,27,28)(H,29,30)/b9-8-/t19-,20+,22-/m0/s1 | UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a |
The University of Tokyo
Curated by ChEMBL
| Assay Description Agonist activity at P2Y10 (unknown origin) transfected in HEK293A cells after 1 hr by TGFalpha shedding assay |
J Med Chem 58: 4204-19 (2015)
Article DOI: 10.1021/jm5020082 BindingDB Entry DOI: 10.7270/Q2Q81FTD |
More data for this Ligand-Target Pair | |
Probable G-protein coupled receptor 174
(Homo sapiens (Human)) | BDBM50096435
(CHEMBL3577163)Show SMILES CCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)COP(O)(=O)O[C@@H](C)[C@H](N)C(O)=O |r| Show InChI InChI=1S/C23H44NO9P/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-21(26)31-17-20(25)18-32-34(29,30)33-19(2)22(24)23(27)28/h8-9,19-20,22,25H,3-7,10-18,24H2,1-2H3,(H,27,28)(H,29,30)/b9-8-/t19-,20+,22-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 589 | n/a | n/a | n/a | n/a |
The University of Tokyo
Curated by ChEMBL
| Assay Description Agonist activity at GPR174 (unknown origin) transfected in HEK293FT cells after 1 hr by TGFalpha shedding assay |
J Med Chem 58: 4204-19 (2015)
Article DOI: 10.1021/jm5020082 BindingDB Entry DOI: 10.7270/Q2Q81FTD |
More data for this Ligand-Target Pair | |