Found 4 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Putative P2Y purinoceptor 10
(Homo sapiens (Human)) | BDBM50096478
(CHEMBL3577180)Show SMILES CCCCCCCCCCCOc1cccc(CCC(=O)OCCCOP(O)(=O)OC[C@H](N)C(O)=O)c1 |r| Show InChI InChI=1S/C21H26N2O5S/c1-28-17-11-13-18(14-12-17)29(26,27)23(15-16-7-3-2-4-8-16)20-10-6-5-9-19(20)21(24)22-25/h2-4,7-8,11-14,19-20,25H,5-6,9-10,15H2,1H3,(H,22,24)/t19-,20?/m1/s1 | UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 32 | n/a | n/a | n/a | n/a |
The University of Tokyo
Curated by ChEMBL
| Assay Description Agonist activity at P2Y10 (unknown origin) transfected in HEK293A cells after 1 hr by TGFalpha shedding assay |
J Med Chem 58: 4204-19 (2015)
Article DOI: 10.1021/jm5020082 BindingDB Entry DOI: 10.7270/Q2Q81FTD |
More data for this Ligand-Target Pair | |
Probable G-protein coupled receptor 174
(Homo sapiens (Human)) | BDBM50096478
(CHEMBL3577180)Show SMILES CCCCCCCCCCCOc1cccc(CCC(=O)OCCCOP(O)(=O)OC[C@H](N)C(O)=O)c1 |r| Show InChI InChI=1S/C21H26N2O5S/c1-28-17-11-13-18(14-12-17)29(26,27)23(15-16-7-3-2-4-8-16)20-10-6-5-9-19(20)21(24)22-25/h2-4,7-8,11-14,19-20,25H,5-6,9-10,15H2,1H3,(H,22,24)/t19-,20?/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
The University of Tokyo
Curated by ChEMBL
| Assay Description Agonist activity at GPR174 (unknown origin) transfected in HEK293FT cells after 1 hr by TGFalpha shedding assay |
J Med Chem 58: 4204-19 (2015)
Article DOI: 10.1021/jm5020082 BindingDB Entry DOI: 10.7270/Q2Q81FTD |
More data for this Ligand-Target Pair | |
Putative P2Y purinoceptor 10
(Homo sapiens (Human)) | BDBM50096478
(CHEMBL3577180)Show SMILES CCCCCCCCCCCOc1cccc(CCC(=O)OCCCOP(O)(=O)OC[C@H](N)C(O)=O)c1 |r| Show InChI InChI=1S/C21H26N2O5S/c1-28-17-11-13-18(14-12-17)29(26,27)23(15-16-7-3-2-4-8-16)20-10-6-5-9-19(20)21(24)22-25/h2-4,7-8,11-14,19-20,25H,5-6,9-10,15H2,1H3,(H,22,24)/t19-,20?/m1/s1 | UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 33 | n/a | n/a | n/a | n/a |
The University of Tokyo
Curated by ChEMBL
| Assay Description Agonist activity at P2Y10 (unknown origin) transfected in HEK293A cells after 1 hr by TGFalpha shedding assay |
J Med Chem 58: 4204-19 (2015)
Article DOI: 10.1021/jm5020082 BindingDB Entry DOI: 10.7270/Q2Q81FTD |
More data for this Ligand-Target Pair | |
Probable G-protein coupled receptor 34
(Homo sapiens (Human)) | BDBM50096478
(CHEMBL3577180)Show SMILES CCCCCCCCCCCOc1cccc(CCC(=O)OCCCOP(O)(=O)OC[C@H](N)C(O)=O)c1 |r| Show InChI InChI=1S/C21H26N2O5S/c1-28-17-11-13-18(14-12-17)29(26,27)23(15-16-7-3-2-4-8-16)20-10-6-5-9-19(20)21(24)22-25/h2-4,7-8,11-14,19-20,25H,5-6,9-10,15H2,1H3,(H,22,24)/t19-,20?/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
The University of Tokyo
Curated by ChEMBL
| Assay Description Agonist activity at GPR34 (unknown origin) transfected in HEK293A cells after 1 hr by TGFalpha shedding assay |
J Med Chem 58: 4204-19 (2015)
Article DOI: 10.1021/jm5020082 BindingDB Entry DOI: 10.7270/Q2Q81FTD |
More data for this Ligand-Target Pair | |