Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 341.8 BDBM50190492

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Amiloride-sensitive sodium channel subunit alpha (Homo sapiens (Human))	BDBM50190492 (CHEMBL210981 | N-(3,5-diamino-6-chloropyrazine-2-c...) Show SMILES CCCCCCCCN=C(N)NC(=O)c1nc(Cl)c(N)nc1N |w:8.7| Show InChI InChI=1S/C14H24ClN7O/c1-2-3-4-5-6-7-8-19-14(18)22-13(23)9-11(16)21-12(17)10(15)20-9/h2-8H2,1H3,(H4,16,17,21)(H3,18,19,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	108	n/a	n/a	n/a	n/a	n/a	n/a
Parion Sciences Inc. Curated by ChEMBL					Assay Description Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assay				J Med Chem 49: 4098-115 (2006) Article DOI: 10.1021/jm051134w BindingDB Entry DOI: 10.7270/Q2FT8KNH
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