Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Carnitine O-palmitoyltransferase 1, muscle isoform
(Rattus norvegicus) | BDBM50122829
((3-Carboxy-2-octyloxycarbonylamino-propyl)-trimeth...)Show SMILES CCCCCCCCOC(=O)N[C@@H](CC([O-])=O)C[N+](C)(C)C Show InChI InChI=1S/C16H32N2O4/c1-5-6-7-8-9-10-11-22-16(21)17-14(12-15(19)20)13-18(2,3)4/h14H,5-13H2,1-4H3,(H-,17,19,20,21)/t14-/m0/s1 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Sigma Tau Pharmaceutical Industries S.p.A.
Curated by ChEMBL
| Assay Description In vitro inhibition of [14C]-palmitoyl-CoA and carnitine binding to carnitine palmitoyltransferase I of rat heart mitochondria |
J Med Chem 46: 303-9 (2003)
Article DOI: 10.1021/jm020979u BindingDB Entry DOI: 10.7270/Q2N015WM |
More data for this Ligand-Target Pair | |
Carnitine O-palmitoyltransferase 1, liver isoform
(Rattus norvegicus) | BDBM50122829
((3-Carboxy-2-octyloxycarbonylamino-propyl)-trimeth...)Show SMILES CCCCCCCCOC(=O)N[C@@H](CC([O-])=O)C[N+](C)(C)C Show InChI InChI=1S/C16H32N2O4/c1-5-6-7-8-9-10-11-22-16(21)17-14(12-15(19)20)13-18(2,3)4/h14H,5-13H2,1-4H3,(H-,17,19,20,21)/t14-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Sigma Tau Pharmaceutical Industries S.p.A.
Curated by ChEMBL
| Assay Description Inhibition of [14C]-palmitoyl-CoA and carnitine binding to carnitine palmitoyltransferase I from rat liver mitochondria |
J Med Chem 46: 303-9 (2003)
Article DOI: 10.1021/jm020979u BindingDB Entry DOI: 10.7270/Q2N015WM |
More data for this Ligand-Target Pair | |