Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Asialoglycoprotein receptor 1
(Homo sapiens (Human)) | BDBM408860
(US10376531, Compound 21 | US10813942, Compound 21)Show SMILES CCCCCCOC[C@@]12CO[C@@H](O1)[C@H](NC(C)=O)[C@@H](O)[C@H]2O |r| Show InChI InChI=1S/C15H27NO6/c1-3-4-5-6-7-20-8-15-9-21-14(22-15)11(16-10(2)17)12(18)13(15)19/h11-14,18-19H,3-9H2,1-2H3,(H,16,17)/t11-,12-,13-,14?,15+/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
US Patent
| Assay Description All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200... |
US Patent US10813942 (2020)
BindingDB Entry DOI: 10.7270/Q28G8PSJ |
More data for this Ligand-Target Pair | |
Asialoglycoprotein receptor 1
(Homo sapiens (Human)) | BDBM408860
(US10376531, Compound 21 | US10813942, Compound 21)Show SMILES CCCCCCOC[C@@]12CO[C@@H](O1)[C@H](NC(C)=O)[C@@H](O)[C@H]2O |r| Show InChI InChI=1S/C15H27NO6/c1-3-4-5-6-7-20-8-15-9-21-14(22-15)11(16-10(2)17)12(18)13(15)19/h11-14,18-19H,3-9H2,1-2H3,(H,16,17)/t11-,12-,13-,14?,15+/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | n/a | 3.40E+3 | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
US Patent
| Assay Description All SPR measurements with compounds were performed using a Biacore 3000 (GE Healthcare) at 25° C. Biotinylated ASGPR was immobilized typically at 200... |
US Patent US10376531 (2019)
BindingDB Entry DOI: 10.7270/Q2542QZJ |
More data for this Ligand-Target Pair | |